iopamidol-7189 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the iopamidol-7189 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
AKAP12 A kinase (PRKA) anchor protein 12
AKR1C2 aldo-keto reductase family 1, member C2
APOC1 apolipoprotein C-I
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
AVL9 AVL9 homolog (S. cerevisiase)
BCOR BCL6 corepressor
C10ORF88 chromosome 10 open reading frame 88
CAPG capping protein (actin filament), gelsolin-like
CD46 CD46 molecule, complement regulatory protein
CDK2 cyclin-dependent kinase 2
CLDN1 claudin 1
COPA coatomer protein complex, subunit alpha
CPD carboxypeptidase D
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSNK1A1 casein kinase 1, alpha 1
CYLD cylindromatosis (turban tumor syndrome)
DENND4A DENN/MADD domain containing 4A
DGKE diacylglycerol kinase, epsilon 64kDa
DGKG diacylglycerol kinase, gamma 90kDa
DLG1 discs, large homolog 1 (Drosophila)
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
EEA1 early endosome antigen 1
EGR3 early growth response 3
ELSPBP1 epididymal sperm binding protein 1
EMC1 ER membrane protein complex subunit 1
ESR1 estrogen receptor 1
EXOC5 exocyst complex component 5
GID4 GID complex subunit 4
GLRX glutaredoxin (thioltransferase)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GON4L gon-4-like (C. elegans)
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HIP1 huntingtin interacting protein 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
IFT122 intraflagellar transport 122
IL21 interleukin 21
ITM2B integral membrane protein 2B
KRT17 keratin 17, type I
LOC642236 FSHD region gene 1 pseudogene
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
LZTFL1 leucine zipper transcription factor-like 1
MAGEH1 melanoma antigen family H1
MAN1A1 mannosidase, alpha, class 1A, member 1
MANEA mannosidase, endo-alpha
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MBD3 methyl-CpG binding domain protein 3
MBNL2 muscleblind-like splicing regulator 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
MCM3AP minichromosome maintenance complex component 3 associated protein
MDM4 MDM4, p53 regulator
MLF1 myeloid leukemia factor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEK2 NIMA-related kinase 2
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL2 NIPA-like domain containing 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
OTUB1 OTU deubiquitinase, ubiquitin aldehyde binding 1
PER3 period circadian clock 3
PLK4 polo-like kinase 4
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PTBP3 polypyrimidine tract binding protein 3
PTPN12 protein tyrosine phosphatase, non-receptor type 12
QKI QKI, KH domain containing, RNA binding
RAB28 RAB28, member RAS oncogene family
RAB29 RAB29, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RCAN1 regulator of calcineurin 1
RHOQ ras homolog family member Q
RNF6 ring finger protein (C3H2C3 type) 6
RPL23AP32 ribosomal protein L23a pseudogene 32
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
RWDD3 RWD domain containing 3
SCAMP1 secretory carrier membrane protein 1
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SKIL SKI-like proto-oncogene
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SOX9 SRY (sex determining region Y)-box 9
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX16 syntaxin 16
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TGFA transforming growth factor, alpha
TMEM38B transmembrane protein 38B
TMEM63A transmembrane protein 63A
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TSFM Ts translation elongation factor, mitochondrial
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WRN Werner syndrome, RecQ helicase-like
WSB1 WD repeat and SOCS box containing 1
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
AP1B1 adaptor-related protein complex 1, beta 1 subunit
ATF3 activating transcription factor 3
BATF basic leucine zipper transcription factor, ATF-like
BBC3 BCL2 binding component 3
C14ORF132 chromosome 14 open reading frame 132
C1ORF106 chromosome 1 open reading frame 106
C7ORF43 chromosome 7 open reading frame 43
CCDC9 coiled-coil domain containing 9
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CENPT centromere protein T
CEP85 centrosomal protein 85kDa
CEP97 centrosomal protein 97kDa
CHKB choline kinase beta
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CLSPN claspin
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DGAT1 diacylglycerol O-acyltransferase 1
DSPP dentin sialophosphoprotein
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EPHA2 EPH receptor A2
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
FAM188A family with sequence similarity 188, member A
FAM192A family with sequence similarity 192, member A
FAM53B family with sequence similarity 53, member B
GAB2 GRB2-associated binding protein 2
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HINFP histone H4 transcription factor
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-J major histocompatibility complex, class I, J (pseudogene)
INF2 inverted formin, FH2 and WH2 domain containing
IRF1 interferon regulatory factor 1
IRX4 iroquois homeobox 4
ITPKC inositol-trisphosphate 3-kinase C
JMJD4 jumonji domain containing 4
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIF3C kinesin family member 3C
KRT31 keratin 31, type I
LHX1 LIM homeobox 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAST3 microtubule associated serine/threonine kinase 3
MED15 mediator complex subunit 15
MED22 mediator complex subunit 22
MTHFSD methenyltetrahydrofolate synthetase domain containing
NECAB3 N-terminal EF-hand calcium binding protein 3
P3H1 prolyl 3-hydroxylase 1
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PDE12 phosphodiesterase 12
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLD3 phospholipase D family, member 3
PLEKHO2 pleckstrin homology domain containing, family O member 2
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF2 ring finger protein 2
RPAP1 RNA polymerase II associated protein 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCHIP1 schwannomin interacting protein 1
SHB Src homology 2 domain containing adaptor protein B
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMA4 glucuronidase, beta pseudogene
SOX12 SRY (sex determining region Y)-box 12
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SYT17 synaptotagmin XVII
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TICAM1 toll-like receptor adaptor molecule 1
TLN1 talin 1
TLR5 toll-like receptor 5
TMEM132A transmembrane protein 132A
TOM1 target of myb1 (chicken)
TRAF2 TNF receptor-associated factor 2
TRIM66 tripartite motif containing 66
TRIP10 thyroid hormone receptor interactor 10
TTC30A tetratricopeptide repeat domain 30A
VASH1 vasohibin 1
VGF VGF nerve growth factor inducible
VPS9D1 VPS9 domain containing 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBED1 zinc finger, BED-type containing 1
ZNF205 zinc finger protein 205
ZNF574 zinc finger protein 574
ZSCAN9 zinc finger and SCAN domain containing 9