ion channel complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. (Gene Ontology, GO_0034702)
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253 proteins localized to the ion channel complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 0.663342
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1 0.663342
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.663342
KCNMB3 potassium channel subfamily M regulatory beta subunit 3 0.663342
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 0.663342
KCNMB4 potassium channel subfamily M regulatory beta subunit 4 0.663342
SNAP25 synaptosomal-associated protein, 25kDa 0.663342
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.663342
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.663342
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal) 0.663342
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal) 0.663342
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 0.663342
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1 0.663342
CACNG8 calcium channel, voltage-dependent, gamma subunit 8 0.663342
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 0.663342
CACNG6 calcium channel, voltage-dependent, gamma subunit 6 0.663342
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 0.663342
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.663342
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 0.663342
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 0.663342
KCNIP2 Kv channel interacting protein 2 0.663342
CACNB3 calcium channel, voltage-dependent, beta 3 subunit 0.663342
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.663342
LRRC8A leucine rich repeat containing 8 family, member A 0.663342
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.663342
TRPC5 transient receptor potential cation channel, subfamily C, member 5 0.663342
PKD2L1 polycystic kidney disease 2-like 1 0.663342
CACNA1F calcium channel, voltage-dependent, L type, alpha 1F subunit 0.663342
PKD1L1 polycystic kidney disease 1 like 1 0.663342
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.663342
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.663342
SCN4B sodium channel, voltage gated, type IV beta subunit 0.663342
LRRC26 leucine rich repeat containing 26 0.663342
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.663342
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.663342
SCN2B sodium channel, voltage gated, type II beta subunit 0.663342
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.663342
CHRNB3 cholinergic receptor, nicotinic, beta 3 (neuronal) 0.237908
MICU2 mitochondrial calcium uptake 2 0.237908
MICU1 mitochondrial calcium uptake 1 0.237908
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) 0.237908
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.237908
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 0.237908
CNTNAP2 contactin associated protein-like 2 0.237908
SCN10A sodium channel, voltage gated, type X alpha subunit 0.237908
CATSPER4 cation channel, sperm associated 4 0.237908
RYR2 ryanodine receptor 2 (cardiac) 0.237908
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.237908
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 0.237908
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.237908
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.237908
CHRND cholinergic receptor, nicotinic, delta (muscle) 0.237908
CATSPERD catsper channel auxiliary subunit delta 0.237908
CATSPER3 cation channel, sperm associated 3 0.237908
CATSPER2 cation channel, sperm associated 2 0.237908
AKAP9 A kinase (PRKA) anchor protein 9 0.237908
CATSPER1 cation channel, sperm associated 1 0.237908
SCN2A sodium channel, voltage gated, type II alpha subunit 0.237908
KCNG2 potassium channel, voltage gated modifier subfamily G, member 2 0.237908
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.237908
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.237908
SCN5A sodium channel, voltage gated, type V alpha subunit 0.237908
AKAP6 A kinase (PRKA) anchor protein 6 0.237908
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.237908
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit 0.237908
ASPH aspartate beta-hydroxylase 0.237908
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.237908
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8 0.237908
CHRNE cholinergic receptor, nicotinic, epsilon (muscle) 0.237908
PDE4D phosphodiesterase 4D, cAMP-specific 0.237908
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.237908
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 0.237908
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.237908
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4 0.237908
MCU mitochondrial calcium uniporter 0.237908
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2 0.237908
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1 0.237908
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 0.237908
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.237908
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.237908
CACNB2 calcium channel, voltage-dependent, beta 2 subunit 0.237908
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6 0.237908
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.237908
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1 0.237908
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.237908
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.237908
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.237908
KCNC1 potassium channel, voltage gated Shaw related subfamily C, member 1 0.237908
CATSPERG catsper channel auxiliary subunit gamma 0.237908
KCNK6 potassium channel, two pore domain subfamily K, member 6 0.237908
CCDC109B coiled-coil domain containing 109B 0.237908
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal) 0.237908
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 0.237908
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 0.237908
HSPA2 heat shock 70kDa protein 2 0.237908
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.237908
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.237908
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.237908
ANO6 anoctamin 6 0.237908
CATSPERB catsper channel auxiliary subunit beta 0.237908
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 0.237908
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2 0.237908
SCN1B sodium channel, voltage gated, type I beta subunit 0.237908
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.237908
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.237908
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.237908
CASQ2 calsequestrin 2 (cardiac muscle) 0.237908
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.237908
SCN3B sodium channel, voltage gated, type III beta subunit 0.237908
CACNG2 calcium channel, voltage-dependent, gamma subunit 2 0.237908
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.237908
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.237908
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2 0.237908
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.237908
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3 0.237908
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.237908
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.237908
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3 0.237908
BEST4 bestrophin 4 0.098109
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.098109
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 0.098109
KCNT2 potassium channel, sodium activated subfamily T, member 2 0.098109
BEST1 bestrophin 1 0.098109
GABRR3 gamma-aminobutyric acid (GABA) A receptor, rho 3 (gene/pseudogene) 0.098109
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6 0.098109
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1 0.098109
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2 0.098109
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1 0.098109
ANO2 anoctamin 2, calcium activated chloride channel 0.098109
SLC26A6 solute carrier family 26 (anion exchanger), member 6 0.098109
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.098109
CLCC1 chloride channel CLIC-like 1 0.098109
ANO1 anoctamin 1, calcium activated chloride channel 0.098109
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.098109
GLRB glycine receptor, beta 0.098109
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.098109
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 0.098109
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 0.098109
KCNT1 potassium channel, sodium activated subfamily T, member 1 0.098109
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.098109
BEST3 bestrophin 3 0.098109
KCNU1 potassium channel, subfamily U, member 1 0.098109
TTYH1 tweety family member 1 0.098109
TTYH2 tweety family member 2 0.098109
FXYD1 FXYD domain containing ion transport regulator 1 0.098109
FXYD3 FXYD domain containing ion transport regulator 3 0.098109
TTYH3 tweety family member 3 0.098109
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta 0.098109
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.098109
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon 0.098109
GLRA1 glycine receptor, alpha 1 0.098109
STXBP5 syntaxin binding protein 5 (tomosyn) 0.098109
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.098109
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 0.098109
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 0.098109
CLCNKB chloride channel, voltage-sensitive Kb 0.098109
CLCNKA chloride channel, voltage-sensitive Ka 0.098109
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.098109
CLCN2 chloride channel, voltage-sensitive 2 0.098109
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 0.098109
GLRA2 glycine receptor, alpha 2 0.098109
GLRA4 glycine receptor, alpha 4 0.098109
BEST2 bestrophin 2 0.098109
CLIC6 chloride intracellular channel 6 0.098109
CLIC4 chloride intracellular channel 4 0.098109
CLIC5 chloride intracellular channel 5 0.098109
CLIC2 chloride intracellular channel 2 0.098109
CLCN1 chloride channel, voltage-sensitive 1 0.098109
CLIC1 chloride intracellular channel 1 0.098109
GLRA3 glycine receptor, alpha 3 0.098109
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.098109
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.098109
CLIC3 chloride intracellular channel 3 0.098109
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1 0.03318
SCN7A sodium channel, voltage gated, type VII alpha subunit 0.03318
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2 0.03318
CACNG4 calcium channel, voltage-dependent, gamma subunit 4 0.03318
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A 0.03318
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4 0.03318
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 0.03318
KCNG3 potassium channel, voltage gated modifier subfamily G, member 3 0.03318
SCN4A sodium channel, voltage gated, type IV alpha subunit 0.03318
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 0.03318
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.03318
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.03318
TRDN triadin 0.03318
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.03318
CHRNA9 cholinergic receptor, nicotinic, alpha 9 (neuronal) 0.03318
CNTN2 contactin 2 (axonal) 0.03318
CNGB1 cyclic nucleotide gated channel beta 1 0.03318
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 0.03318
SCN11A sodium channel, voltage gated, type XI alpha subunit 0.03318
CNTNAP1 contactin associated protein 1 0.03318
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.03318
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 0.03318
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.03318
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 0.03318
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2 0.03318
SCN3A sodium channel, voltage gated, type III alpha subunit 0.03318
KCNIP1 Kv channel interacting protein 1 0.03318
KCNV1 potassium channel, voltage gated modifier subfamily V, member 1 0.03318
KCNV2 potassium channel, voltage gated modifier subfamily V, member 2 0.03318
KCNA7 potassium channel, voltage gated shaker related subfamily A, member 7 0.03318
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.03318
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 0.03318
C1ORF101 chromosome 1 open reading frame 101 0.03318
SCN1A sodium channel, voltage gated, type I alpha subunit 0.03318
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.03318
KCNA10 potassium channel, voltage gated shaker related subfamily A, member 10 0.03318
KCNMB1 potassium channel subfamily M regulatory beta subunit 1 0.03318
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.008279
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.008279
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.008279
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.008279
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.007494
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.007494
GRIN3B glutamate receptor, ionotropic, N-methyl-D-aspartate 3B 0.007494
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 0.007494
CNIH3 cornichon family AMPA receptor auxiliary protein 3 0.007494
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.007494
CNIH2 cornichon family AMPA receptor auxiliary protein 2 0.007494
GRIA3 glutamate receptor, ionotropic, AMPA 3 0.007494
PTK2B protein tyrosine kinase 2 beta 0.006587
GRIK3 glutamate receptor, ionotropic, kainate 3 0.006587
GRIK2 glutamate receptor, ionotropic, kainate 2 0.006587
GRIK1 glutamate receptor, ionotropic, kainate 1 0.006587
DLG4 discs, large homolog 4 (Drosophila) 0.006587
GRIK4 glutamate receptor, ionotropic, kainate 4 0.006587
GRIK5 glutamate receptor, ionotropic, kainate 5 0.006587
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.006587
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.006587
OLFM3 olfactomedin 3 0.005272
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1 0.005272
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.005272
NLGN1 neuroligin 1 0.005272
ABHD6 abhydrolase domain containing 6 0.005272
OLFM2 olfactomedin 2 0.005272
OLFM1 olfactomedin 1 0.005272
CPT1C carnitine palmitoyltransferase 1C 0.005272
SHANK1 SH3 and multiple ankyrin repeat domains 1 0.005272
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) 0.005272
EPS8 epidermal growth factor receptor pathway substrate 8 0.005272
LRRTM4 leucine rich repeat transmembrane neuronal 4 0.005272
DLG3 discs, large homolog 3 (Drosophila) 0.005272
ABHD12 abhydrolase domain containing 12 0.005272
VWC2 von Willebrand factor C domain containing 2 0.005272
PORCN porcupine homolog (Drosophila) 0.005272
SHISA6 shisa family member 6 0.005272
SHISA9 shisa family member 9 0.005272
VWC2L von Willebrand factor C domain containing protein 2-like 0.005272
NRN1 neuritin 1 0.005272
GRID1 glutamate receptor, ionotropic, delta 1 0.004382
GRID2 glutamate receptor, ionotropic, delta 2 0.004382