iodixanol-4848 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the iodixanol-4848 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AHNAK2 AHNAK nucleoprotein 2
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATXN2L ataxin 2-like
BCAT1 branched chain amino-acid transaminase 1, cytosolic
BLZF1 basic leucine zipper nuclear factor 1
BRIX1 BRX1, biogenesis of ribosomes
BTF3P11 basic transcription factor 3 pseudogene 11
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CA4 carbonic anhydrase IV
CAPN10 calpain 10
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CBX8 chromobox homolog 8
CCNG2 cyclin G2
CD34 CD34 molecule
CDC25C cell division cycle 25C
CEP164 centrosomal protein 164kDa
COMMD10 COMM domain containing 10
CRY2 cryptochrome circadian clock 2
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNAL4 dynein, axonemal, light chain 4
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DUSP4 dual specificity phosphatase 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
E2F8 E2F transcription factor 8
EAF2 ELL associated factor 2
EPHA3 EPH receptor A3
FAS Fas cell surface death receptor
FRMD4A FERM domain containing 4A
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAMT guanidinoacetate N-methyltransferase
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GPATCH2L G patch domain containing 2-like
GPM6B glycoprotein M6B
GPR1 G protein-coupled receptor 1
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HBS1L HBS1-like translational GTPase
HIST1H1E histone cluster 1, H1e
HOXA4 homeobox A4
HSF1 heat shock transcription factor 1
KLF3 Kruppel-like factor 3 (basic)
LENEP lens epithelial protein
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED4 mediator complex subunit 4
MFAP3L microfibrillar-associated protein 3-like
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MTM1 myotubularin 1
NCKIPSD NCK interacting protein with SH3 domain
NFRKB nuclear factor related to kappaB binding protein
NHLRC2 NHL repeat containing 2
NPTX1 neuronal pentraxin I
PAX9 paired box 9
PCDHB13 protocadherin beta 13
PEX1 peroxisomal biogenesis factor 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
POM121L2 POM121 transmembrane nucleoporin-like 2
PSG9 pregnancy specific beta-1-glycoprotein 9
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTHLH parathyroid hormone-like hormone
QKI QKI, KH domain containing, RNA binding
RAB6B RAB6B, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
RHOBTB2 Rho-related BTB domain containing 2
RIMS2 regulating synaptic membrane exocytosis 2
RNFT1 ring finger protein, transmembrane 1
RWDD3 RWD domain containing 3
S100A8 S100 calcium binding protein A8
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIRT5 sirtuin 5
SLC35A5 solute carrier family 35, member A5
SMAD6 SMAD family member 6
SOGA1 suppressor of glucose, autophagy associated 1
SOS2 son of sevenless homolog 2 (Drosophila)
SRSF7 serine/arginine-rich splicing factor 7
STXBP3 syntaxin binding protein 3
TBRG4 transforming growth factor beta regulator 4
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM2D1 TM2 domain containing 1
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM23 tripartite motif containing 23
TRIM36 tripartite motif containing 36
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
UBA6 ubiquitin-like modifier activating enzyme 6
UBOX5 U-box domain containing 5
VAMP4 vesicle-associated membrane protein 4
WDR76 WD repeat domain 76
WIPF1 WAS/WASL interacting protein family, member 1
WNK1 WNK lysine deficient protein kinase 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF37BP zinc finger protein 37B, pseudogene
ZNF394 zinc finger protein 394
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGRE5 adhesion G protein-coupled receptor E5
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALPK1 alpha-kinase 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
APLP1 amyloid beta (A4) precursor-like protein 1
ARR3 arrestin 3, retinal (X-arrestin)
ARRB1 arrestin, beta 1
ASIC1 acid sensing (proton gated) ion channel 1
C11ORF63 chromosome 11 open reading frame 63
C17ORF80 chromosome 17 open reading frame 80
C1ORF21 chromosome 1 open reading frame 21
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC186 coiled-coil domain containing 186
CENPO centromere protein O
CORO7 coronin 7
CPED1 cadherin-like and PC-esterase domain containing 1
CRLF1 cytokine receptor-like factor 1
DEAF1 DEAF1 transcription factor
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ERCC2 excision repair cross-complementation group 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXO5 exonuclease 5
FAM131A family with sequence similarity 131, member A
FAM169A family with sequence similarity 169, member A
FAM189A2 family with sequence similarity 189, member A2
FAM222B family with sequence similarity 222, member B
FGD1 FYVE, RhoGEF and PH domain containing 1
FKBP5 FK506 binding protein 5
FLJ21369 uncharacterized protein FLJ21369
GEMIN8 gem (nuclear organelle) associated protein 8
GRTP1 growth hormone regulated TBC protein 1
HDAC11 histone deacetylase 11
HDAC7 histone deacetylase 7
HIST1H4D histone cluster 1, H4d
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMOX1 heme oxygenase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HYAL3 hyaluronoglucosaminidase 3
HYI hydroxypyruvate isomerase (putative)
IGSF1 immunoglobulin superfamily, member 1
IL2 interleukin 2
INCENP inner centromere protein antigens 135/155kDa
INPP5J inositol polyphosphate-5-phosphatase J
IPO8 importin 8
IRF6 interferon regulatory factor 6
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCTD17 potassium channel tetramerization domain containing 17
KCTD20 potassium channel tetramerization domain containing 20
KLF13 Kruppel-like factor 13
KRI1 KRI1 homolog (S. cerevisiae)
LAX1 lymphocyte transmembrane adaptor 1
LOXL3 lysyl oxidase-like 3
LTC4S leukotriene C4 synthase
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTSS1L metastasis suppressor 1-like
MYO1F myosin IF
PADI1 peptidyl arginine deiminase, type I
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRF1 perforin 1 (pore forming protein)
PRR4 proline rich 4 (lacrimal)
PTCD2 pentatricopeptide repeat domain 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RPL10L ribosomal protein L10-like
SAMD9 sterile alpha motif domain containing 9
SETD8 SET domain containing (lysine methyltransferase) 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SMG9 SMG9 nonsense mediated mRNA decay factor
SMR3A submaxillary gland androgen regulated protein 3A
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SREK1IP1 SREK1-interacting protein 1
STRA6 stimulated by retinoic acid 6
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCP10 t-complex 10
TFF2 trefoil factor 2
TMEM45A transmembrane protein 45A
TSPYL2 TSPY-like 2
UPK2 uroplakin 2
UPP1 uridine phosphorylase 1
VASH2 vasohibin 2
WDR25 WD repeat domain 25
ZBTB22 zinc finger and BTB domain containing 22
ZBTB44 zinc finger and BTB domain containing 44
ZNF205 zinc finger protein 205
ZNF253 zinc finger protein 253
ZNF34 zinc finger protein 34
ZNF510 zinc finger protein 510
ZNF574 zinc finger protein 574