iocetamic acid-4425 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the iocetamic acid-4425 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAM22 ADAM metallopeptidase domain 22
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADRA1D adrenoceptor alpha 1D
ALDOB aldolase B, fructose-bisphosphate
ALPPL2 alkaline phosphatase, placental-like 2
ANXA2P1 annexin A2 pseudogene 1
ARHGAP26 Rho GTPase activating protein 26
ASIC1 acid sensing (proton gated) ion channel 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1QB complement component 1, q subcomponent, B chain
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPZB capping protein (actin filament) muscle Z-line, beta
CASP10 caspase 10, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCR1 chemokine (C-C motif) receptor 1
CDH8 cadherin 8, type 2
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL8A2 collagen, type VIII, alpha 2
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CSF1 colony stimulating factor 1 (macrophage)
CXORF21 chromosome X open reading frame 21
DAPK2 death-associated protein kinase 2
DENND5B DENN/MADD domain containing 5B
DGCR8 DGCR8 microprocessor complex subunit
DOCK6 dedicator of cytokinesis 6
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
FOXP3 forkhead box P3
FPR1 formyl peptide receptor 1
GJA4 gap junction protein, alpha 4, 37kDa
GLIPR1 GLI pathogenesis-related 1
GM2A GM2 ganglioside activator
GRIP2 glutamate receptor interacting protein 2
HFE hemochromatosis
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HOXA11 homeobox A11
HOXD11 homeobox D11
HYAL1 hyaluronoglucosaminidase 1
IFFO1 intermediate filament family orphan 1
IFNW1 interferon, omega 1
IL21R interleukin 21 receptor
IL2RB interleukin 2 receptor, beta
KANK1 KN motif and ankyrin repeat domains 1
KCNK10 potassium channel, two pore domain subfamily K, member 10
KDM5B lysine (K)-specific demethylase 5B
KIAA1456 KIAA1456
KIF25-AS1 KIF25 antisense RNA 1
KIFC3 kinesin family member C3
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KRT16 keratin 16, type I
LOC51145 uncharacterized LOC51145
LONRF3 LON peptidase N-terminal domain and ring finger 3
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MED25 mediator complex subunit 25
MET MET proto-oncogene, receptor tyrosine kinase
MFAP5 microfibrillar associated protein 5
MIP major intrinsic protein of lens fiber
MIR622 microRNA 622
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MVB12B multivesicular body subunit 12B
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCR3 natural cytotoxicity triggering receptor 3
NSUN6 NOP2/Sun domain family, member 6
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH1 protocadherin 1
PDE4DIP phosphodiesterase 4D interacting protein
PHF20L1 PHD finger protein 20-like 1
PLCB2 phospholipase C, beta 2
PLD1 phospholipase D1, phosphatidylcholine-specific
POFUT1 protein O-fucosyltransferase 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PTRF polymerase I and transcript release factor
PVT1 Pvt1 oncogene (non-protein coding)
RARA retinoic acid receptor, alpha
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPL10 ribosomal protein L10
S100A7 S100 calcium binding protein A7
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SLC17A2 solute carrier family 17, member 2
SOAT2 sterol O-acyltransferase 2
SOGA1 suppressor of glucose, autophagy associated 1
SPTBN2 spectrin, beta, non-erythrocytic 2
STOML1 stomatin (EPB72)-like 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TNS1 tensin 1
TRPM2 transient receptor potential cation channel, subfamily M, member 2
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
WDR78 WD repeat domain 78
ZNF335 zinc finger protein 335
ZNF407 zinc finger protein 407
ZRSR1 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM2 ADAM metallopeptidase domain 2
ADM adrenomedullin
AMT aminomethyltransferase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B9D2 B9 protein domain 2
BATF basic leucine zipper transcription factor, ATF-like
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C1ORF21 chromosome 1 open reading frame 21
C1ORF54 chromosome 1 open reading frame 54
C3 complement component 3
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC64 coiled-coil domain containing 64
CLSTN2 calsyntenin 2
CNTNAP1 contactin associated protein 1
CORT cortistatin
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DGAT1 diacylglycerol O-acyltransferase 1
DGKQ diacylglycerol kinase, theta 110kDa
DLK2 delta-like 2 homolog (Drosophila)
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DPY19L1P1 DPY19L1 pseudogene 1
DTX2 deltex 2, E3 ubiquitin ligase
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
FAM214B family with sequence similarity 214, member B
FBXO2 F-box protein 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FGL1 fibrinogen-like 1
FLJ11710 uncharacterized protein FLJ11710
GK2 glycerol kinase 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR157 G protein-coupled receptor 157
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HIRA histone cell cycle regulator
HOXB2 homeobox B2
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KIAA0754 KIAA0754
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KPNA5 karyopherin alpha 5 (importin alpha 6)
KREMEN2 kringle containing transmembrane protein 2
LMNB1 lamin B1
LOC157562 uncharacterized LOC157562
LRRC16A leucine rich repeat containing 16A
LY6G6C lymphocyte antigen 6 complex, locus G6C
MEFV Mediterranean fever
MFSD11 major facilitator superfamily domain containing 11
N4BP3 NEDD4 binding protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NPY4R neuropeptide Y receptor Y4
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCDHGA10 protocadherin gamma subfamily A, 10
PELI1 pellino E3 ubiquitin protein ligase 1
PLCD1 phospholipase C, delta 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RNF122 ring finger protein 122
SAV1 salvador family WW domain containing protein 1
SEC14L5 SEC14-like 5 (S. cerevisiae)
SH2B3 SH2B adaptor protein 3
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNTA1 syntrophin, alpha 1
SPAG4 sperm associated antigen 4
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR2B small proline-rich protein 2B
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
STK16 serine/threonine kinase 16
STRA6 stimulated by retinoic acid 6
SYCP2 synaptonemal complex protein 2
TAOK1 TAO kinase 1
TBL1Y transducin (beta)-like 1, Y-linked
TMEM120B transmembrane protein 120B
TMEM209 transmembrane protein 209
TPK1 thiamin pyrophosphokinase 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSGA10 testis specific, 10
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF532 zinc finger protein 532
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862