iocetamic acid-3361 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the iocetamic acid-3361 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AFF1 AF4/FMR2 family, member 1
AHNAK2 AHNAK nucleoprotein 2
APOM apolipoprotein M
ARHGAP25 Rho GTPase activating protein 25
ARID1A AT rich interactive domain 1A (SWI-like)
ARPIN actin-related protein 2/3 complex inhibitor
ATG3 autophagy related 3
BRS3 bombesin-like receptor 3
BST1 bone marrow stromal cell antigen 1
C19ORF66 chromosome 19 open reading frame 66
C1QB complement component 1, q subcomponent, B chain
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CCKAR cholecystokinin A receptor
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD200 CD200 molecule
CERS4 ceramide synthase 4
CFAP70 cilia and flagella associated protein 70
CHAT choline O-acetyltransferase
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC11A C-type lectin domain family 11, member A
CNPY4 canopy FGF signaling regulator 4
COL5A2 collagen, type V, alpha 2
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor
CRMP1 collapsin response mediator protein 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DFNB31 deafness, autosomal recessive 31
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DNALI1 dynein, axonemal, light intermediate chain 1
DPF1 D4, zinc and double PHD fingers family 1
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
ELL elongation factor RNA polymerase II
EMP3 epithelial membrane protein 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FBXO40 F-box protein 40
FGF16 fibroblast growth factor 16
FHL1 four and a half LIM domains 1
FKRP fukutin related protein
FN1 fibronectin 1
GLRX glutaredoxin (thioltransferase)
GLS glutaminase
HEXA-AS1 HEXA antisense RNA 1
HFE hemochromatosis
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HSF2BP heat shock transcription factor 2 binding protein
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGFBP5 insulin-like growth factor binding protein 5
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA9 integrin, alpha 9
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA1109 KIAA1109
LEFTY2 left-right determination factor 2
LGALS4 lectin, galactoside-binding, soluble, 4
LIMD1 LIM domains containing 1
LOXL2 lysyl oxidase-like 2
MATN3 matrilin 3
MED16 mediator complex subunit 16
MST1R macrophage stimulating 1 receptor
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEUROD4 neuronal differentiation 4
NPTX2 neuronal pentraxin II
NR4A1 nuclear receptor subfamily 4, group A, member 1
OASL 2'-5'-oligoadenylate synthetase-like
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PADI3 peptidyl arginine deiminase, type III
PCDHGA3 protocadherin gamma subfamily A, 3
PER1 period circadian clock 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
POMT2 protein-O-mannosyltransferase 2
PRLR prolactin receptor
PTK2B protein tyrosine kinase 2 beta
RAB6B RAB6B, member RAS oncogene family
RASIP1 Ras interacting protein 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SFTPB surfactant protein B
SIPA1 signal-induced proliferation-associated 1
SOCS3 suppressor of cytokine signaling 3
SPEG SPEG complex locus
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPRR2B small proline-rich protein 2B
TAGLN3 transgelin 3
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAS2R10 taste receptor, type 2, member 10
TGM2 transglutaminase 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLDC1 TBC/LysM-associated domain containing 1
TMLHE trimethyllysine hydroxylase, epsilon
TPMT thiopurine S-methyltransferase
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN9 tetraspanin 9
ZCCHC24 zinc finger, CCHC domain containing 24
ZNF589 zinc finger protein 589
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACTL8 actin-like 8
ADCK4 aarF domain containing kinase 4
ADCY7 adenylate cyclase 7
AGO3 argonaute RISC catalytic component 3
ALS2CL ALS2 C-terminal like
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAHCC1 BAH domain and coiled-coil containing 1
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
C2ORF27A chromosome 2 open reading frame 27A
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBX8 chromobox homolog 8
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLIP4 CAP-GLY domain containing linker protein family, member 4
CPPED1 calcineurin-like phosphoesterase domain containing 1
CUL9 cullin 9
CUZD1 CUB and zona pellucida-like domains 1
CXORF56 chromosome X open reading frame 56
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DGAT1 diacylglycerol O-acyltransferase 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DOC2A double C2-like domains, alpha
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ENO3 enolase 3 (beta, muscle)
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ETAA1 Ewing tumor-associated antigen 1
FLJ11710 uncharacterized protein FLJ11710
FRK fyn-related Src family tyrosine kinase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GPR19 G protein-coupled receptor 19
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA4 homeobox A4
HOXC11 homeobox C11
HOXC5 homeobox C5
IL22 interleukin 22
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2 interferon regulatory factor 2
KIAA0319L KIAA0319-like
KIAA0754 KIAA0754
KLF3 Kruppel-like factor 3 (basic)
LARP6 La ribonucleoprotein domain family, member 6
LIME1 Lck interacting transmembrane adaptor 1
LPXN leupaxin
LRRC61 leucine rich repeat containing 61
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MYO1F myosin IF
MYOZ3 myozenin 3
NOD1 nucleotide-binding oligomerization domain containing 1
PACS1 phosphofurin acidic cluster sorting protein 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITX2 paired-like homeodomain 2
PLA2G10 phospholipase A2, group X
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
QDPR quinoid dihydropteridine reductase
QTRT1 queuine tRNA-ribosyltransferase 1
RAD54L2 RAD54-like 2 (S. cerevisiae)
REV1 REV1, polymerase (DNA directed)
RNF122 ring finger protein 122
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCN1B sodium channel, voltage gated, type I beta subunit
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SPINK5 serine peptidase inhibitor, Kazal type 5
SPRY2 sprouty homolog 2 (Drosophila)
SPTBN2 spectrin, beta, non-erythrocytic 2
SRPX sushi-repeat containing protein, X-linked
SYNC syncoilin, intermediate filament protein
TEAD3 TEA domain family member 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM180 transmembrane protein 180
TMEM184C transmembrane protein 184C
TYRP1 tyrosinase-related protein 1
UNC93B1 unc-93 homolog B1 (C. elegans)
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
XAB2 XPA binding protein 2
ZNF280D zinc finger protein 280D
ZNF324 zinc finger protein 324
ZNF358 zinc finger protein 358
ZNF574 zinc finger protein 574
ZNF580 zinc finger protein 580
ZNF701 zinc finger protein 701
ZSWIM1 zinc finger, SWIM-type containing 1