intrinsic cardiomyopathy Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A cardiomyopathy that is characterized as weakness in the muscle of the heart that is not due to an identifiable external cause. (Human Disease Ontology, DOID_0060036)
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Genes

751 genes co-occuring with the disease intrinsic cardiomyopathy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
MYBPC3 myosin binding protein C, cardiac 2.75987
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 2.53691
MYH7 myosin, heavy chain 7, cardiac muscle, beta 2.51627
TNNT2 troponin T type 2 (cardiac) 2.3107
TPM1 tropomyosin 1 (alpha) 2.26059
LMNA lamin A/C 2.20043
PLN phospholamban 2.14022
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 2.06171
TNNI3 troponin I type 3 (cardiac) 2.03876
ACE angiotensin I converting enzyme 1.94924
MYBPC2 myosin binding protein C, fast type 1.89082
DMD dystrophin 1.86415
TTN titin 1.86049
NPPA natriuretic peptide A 1.82278
ADRB1 adrenoceptor beta 1 1.80111
PKP2 plakophilin 2 1.7903
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 1.75096
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 1.71636
MYL2 myosin, light chain 2, regulatory, cardiac, slow 1.6669
DNAH8 dynein, axonemal, heavy chain 8 1.65925
ACTC1 actin, alpha, cardiac muscle 1 1.61799
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 1.60905
LAMP2 lysosomal-associated membrane protein 2 1.57245
RYR2 ryanodine receptor 2 (cardiac) 1.54451
RBM20 RNA binding motif protein 20 1.54274
TAZ tafazzin 1.49745
NPPB natriuretic peptide B 1.48779
SCN5A sodium channel, voltage gated, type V alpha subunit 1.47638
DSG2 desmoglein 2 1.47418
JPH2 junctophilin 2 1.46891
DSP desmoplakin 1.45616
EMD emerin 1.40833
SCO2 SCO2 cytochrome c oxidase assembly protein 1.4022
JUP junction plakoglobin 1.36161
MYOZ2 myozenin 2 1.34112
VCL vinculin 1.31755
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.31668
GAA glucosidase, alpha; acid 1.30838
CASQ2 calsequestrin 2 (cardiac muscle) 1.30226
TPM3 tropomyosin 3 1.28523
APEH acylaminoacyl-peptide hydrolase 1.26865
ALMS1 Alstrom syndrome protein 1 1.26342
GJA1 gap junction protein, alpha 1, 43kDa 1.25689
DSC2 desmocollin 2 1.24993
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle) 1.23212
MYPN myopalladin 1.22562
FXN frataxin 1.19661
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.19143
TNF tumor necrosis factor 1.18712
TMEM70 transmembrane protein 70 1.18109
LDB3 LIM domain binding 3 1.17593
TCAP titin-cap 1.17292
TNNI1 troponin I type 1 (skeletal, slow) 1.1588
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.15325
SPIC Spi-C transcription factor (Spi-1/PU.1 related) 1.12403
CACTIN cactin, spliceosome C complex subunit 1.0816
TTR transthyretin 1.07992
MYOM2 myomesin 2 1.03914
CRIP3 cysteine-rich protein 3 1.00921
SRF serum response factor (c-fos serum response element-binding transcription factor) 1.00921
CXADR coxsackie virus and adenovirus receptor 0.996549
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 0.988957
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 0.986849
GRB2 growth factor receptor-bound protein 2 0.978848
REN renin 0.977165
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF 0.9717
FHOD3 formin homology 2 domain containing 3 0.9696
DNAJC19 DnaJ (Hsp40) homolog, subfamily C, member 19 0.95996
IGF1 insulin-like growth factor 1 (somatomedin C) 0.952021
GATA4 GATA binding protein 4 0.948685
ACTN2 actinin, alpha 2 0.947435
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.94577
RYR1 ryanodine receptor 1 (skeletal) 0.937044
COX15 cytochrome c oxidase assembly homolog 15 (yeast) 0.93497
FHL1 four and a half LIM domains 1 0.928346
TIMP1 TIMP metallopeptidase inhibitor 1 0.923387
CAV3 caveolin 3 0.914727
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.913492
LRRC10 leucine rich repeat containing 10 0.907731
DNM2 dynamin 2 0.904854
BAG3 BCL2-associated athanogene 3 0.898693
GLA galactosidase, alpha 0.896641
NEBL nebulette 0.894589
MMP2 matrix metallopeptidase 2 0.88393
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.880243
ADRB2 adrenoceptor beta 2, surface 0.874919
DOLK dolichol kinase 0.868777
OPN3 opsin 3 0.865912
CD4 CD4 molecule 0.852811
ACADVL acyl-CoA dehydrogenase, very long chain 0.847898
RGS18 regulator of G-protein signaling 18 0.842982
CRYAB crystallin, alpha B 0.842573
MMP9 matrix metallopeptidase 9 0.840934
ADCY2 adenylate cyclase 2 (brain) 0.836017
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 0.830689
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.820026
IL6 interleukin 6 0.817565
MYEF2 myelin expression factor 2 0.815104
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.811821
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.797052
MYOM1 myomesin 1 0.791721
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 0.791311
CRP C-reactive protein, pentraxin-related 0.784345
MMP1 matrix metallopeptidase 1 0.778613
NEXN nexilin (F actin binding protein) 0.778613
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.776568
COA5 cytochrome c oxidase assembly factor 5 0.774932
ISM2 isthmin 2 0.774932
DSC3 desmocollin 3 0.774523
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.768393
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase 0.765127
GATAD1 GATA zinc finger domain containing 1 0.763086
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.762271
CS citrate synthase 0.756971
ATP11A ATPase, class VI, type 11A 0.754527
FHL2 four and a half LIM domains 2 0.753713
COA6 cytochrome c oxidase assembly factor 6 0.752898
MYLK4 myosin light chain kinase family, member 4 0.752898
COMMD4 COMM domain containing 4 0.752898
MYL12B myosin, light chain 12B, regulatory 0.750864
CHRM2 cholinergic receptor, muscarinic 2 0.747204
MYOCD myocardin 0.745578
SCO1 SCO1 cytochrome c oxidase assembly protein 0.735838
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.735433
EDN1 endothelin 1 0.730976
TRDN triadin 0.729762
CTF1 cardiotrophin 1 0.723694
NKX2-5 NK2 homeobox 5 0.715618
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.713601
FKRP fukutin related protein 0.708364
HLA-C major histocompatibility complex, class I, C 0.705949
NOS3 nitric oxide synthase 3 (endothelial cell) 0.705547
PDLIM3 PDZ and LIM domain 3 0.70434
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.703134
LIMS2 LIM and senescent cell antigen-like domains 2 0.701526
AGTR1 angiotensin II receptor, type 1 0.699116
SOD2 superoxide dismutase 2, mitochondrial 0.698313
RAVER1 ribonucleoprotein, PTB-binding 1 0.696707
ETV3 ets variant 3 0.691094
FIP1L1 factor interacting with PAPOLA and CPSF1 0.689492
TMEM43 transmembrane protein 43 0.687491
TGFB1 transforming growth factor, beta 1 0.685491
HLA-A major histocompatibility complex, class I, A 0.685091
TPTE transmembrane phosphatase with tensin homology 0.682693
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.681894
HRAS Harvey rat sarcoma viral oncogene homolog 0.681495
SOS1 son of sevenless homolog 1 (Drosophila) 0.681096
ACE2 angiotensin I converting enzyme 2 0.680697
ANXA6 annexin A6 0.680697
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.678302
MMP3 matrix metallopeptidase 3 0.671527
LIMS3 LIM and senescent cell antigen-like domains 3 0.664769
DMGDH dimethylglycine dehydrogenase 0.663578
CD36 CD36 molecule (thrombospondin receptor) 0.657234
MYOZ1 myozenin 1 0.654067
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.652484
GNAQ guanine nucleotide binding protein (G protein), q polypeptide 0.650903
KCNIP2 Kv channel interacting protein 2 0.649718
HACD1 3-hydroxyacyl-CoA dehydratase 1 0.648138
HLA-DOB major histocompatibility complex, class II, DO beta 0.646559
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.645375
TIMP4 TIMP metallopeptidase inhibitor 4 0.645375
MT-ATP8 ATP synthase F0 subunit 8 0.637495
GPX1 glutathione peroxidase 1 0.635921
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.635528
TFAM transcription factor A, mitochondrial 0.633956
ANGEL1 angel homolog 1 (Drosophila) 0.628065
EXTL1 exostosin-like glycosyltransferase 1 0.624143
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.61866
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.613965
HRC histidine rich calcium binding protein 0.612792
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 0.606933
NDUFB10 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa 0.6003
BMP10 bone morphogenetic protein 10 0.59874
SURF1 surfeit 1 0.598351
CA5B carbonic anhydrase VB, mitochondrial 0.594843
DTNA dystrobrevin, alpha 0.594454
COX10 COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor 0.591727
TNC tenascin C 0.586665
OCM2 oncomodulin 2 0.585497
ACTA1 actin, alpha 1, skeletal muscle 0.583941
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1 0.581217
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) 0.580439
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 0.577716
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.575772
TBX20 T-box 20 0.574217
MEF2A myocyte enhancer factor 2A 0.571884
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.569552
EYA4 EYA transcriptional coactivator and phosphatase 4 0.564889
AMPD1 adenosine monophosphate deaminase 1 0.564112
MDH1 malate dehydrogenase 1, NAD (soluble) 0.562946
ADRA2C adrenoceptor alpha 2C 0.558285
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.555956
PMM2 phosphomannomutase 2 0.554403
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.552075
DNTT DNA nucleotidylexotransferase 0.546644
IL1B interleukin 1, beta 0.545481
IRF2BPL interferon regulatory factor 2 binding protein-like 0.542379
MYBPC1 myosin binding protein C, slow type 0.538506
FN1 fibronectin 1 0.538118
SCARB2 scavenger receptor class B, member 2 0.531928
HTRA2 HtrA serine peptidase 2 0.531541
HDAC5 histone deacetylase 5 0.529222
AARS2 alanyl-tRNA synthetase 2, mitochondrial 0.528835
CALR3 calreticulin 3 0.526904
DAND5 DAN domain family member 5, BMP antagonist 0.51842
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.518034
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.51611
ADRA1B adrenoceptor alpha 1B 0.515725
IRF6 interferon regulatory factor 6 0.514571
GPX5 glutathione peroxidase 5 0.511112
ALB albumin 0.511112
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.511112
GPX4 glutathione peroxidase 4 0.507657
RHOU ras homolog family member U 0.507273
FHOD1 formin homology 2 domain containing 1 0.506123
DES desmin 0.505739
MDH2 malate dehydrogenase 2, NAD (mitochondrial) 0.502675
TSFM Ts translation elongation factor, mitochondrial 0.501909
CLCN1 chloride channel, voltage-sensitive 1 0.498467
UNC45B unc-45 homolog B (C. elegans) 0.498085
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.495411
SPP1 secreted phosphoprotein 1 0.494648
ILK integrin-linked kinase 0.493122
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 0.492359
GJA5 gap junction protein, alpha 5, 40kDa 0.491215
JUN jun proto-oncogene 0.491215
IL17D interleukin 17D 0.485505
MLIP muscular LMNA-interacting protein 0.485505
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 0.483985
MGAM maltase-glucoamylase 0.479807
INS insulin 0.478668
PRF1 perforin 1 (pore forming protein) 0.476014
MYOT myotilin 0.474119
LMOD2 leiomodin 2 (cardiac) 0.47374
LAMA2 laminin, alpha 2 0.472982
FABP3 fatty acid binding protein 3, muscle and heart 0.472604
CMA1 chymase 1, mast cell 0.468441
MB myoglobin 0.46655
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.461261
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha 0.459373
IL10 interleukin 10 0.454847
FKBP1A FK506 binding protein 1A, 12kDa 0.454093
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 0.453716
JPH1 junctophilin 1 0.453339
TIMP3 TIMP metallopeptidase inhibitor 3 0.450701
EDNRA endothelin receptor type A 0.449947
C16ORF82 chromosome 16 open reading frame 82 0.449571
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2 0.447687
MYH7B myosin, heavy chain 7B, cardiac muscle, beta 0.445429
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.443171
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.442042
RBMXL2 RNA binding motif protein, X-linked-like 2 0.440538
PRKD1 protein kinase D1 0.440538
ACO2 aconitase 2, mitochondrial 0.43753
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.436402
MYO6 myosin VI 0.43227
SCARB1 scavenger receptor class B, member 1 0.431519
BAX BCL2-associated X protein 0.430768
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.429266
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 0.42814
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.427765
FOXD4 forkhead box D4 0.426265
ALPK3 alpha-kinase 3 0.42589
ZNF80 zinc finger protein 80 0.425514
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 0.421016
OCM oncomodulin 0.418019
ERBB4 erb-b2 receptor tyrosine kinase 4 0.413901
AKAP1 A kinase (PRKA) anchor protein 1 0.412779
APLNR apelin receptor 0.410161
PGM1 phosphoglucomutase 1 0.409787
GPAA1 glycosylphosphatidylinositol anchor attachment 1 0.406051
ADM adrenomedullin 0.405678
LDHA lactate dehydrogenase A 0.404557
ICAM1 intercellular adhesion molecule 1 0.403811
IL2RA interleukin 2 receptor, alpha 0.403811
SARDH sarcosine dehydrogenase 0.403811
CCL2 chemokine (C-C motif) ligand 2 0.401945
NPTX2 neuronal pentraxin II 0.401199
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1 0.40008
CREB1 cAMP responsive element binding protein 1 0.399334
COQ4 coenzyme Q4 0.395608
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.394491
FAM188A family with sequence similarity 188, member A 0.394118
XK X-linked Kx blood group 0.392257
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.391141
ANO5 anoctamin 5 0.390025
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic 0.387423
TF transferrin 0.387051
CD79A CD79a molecule, immunoglobulin-associated alpha 0.385936
UTRN utrophin 0.384079
TIMP2 TIMP metallopeptidase inhibitor 2 0.382966
VASP vasodilator-stimulated phosphoprotein 0.382966
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 0.381852
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.379626
SRSF2 serine/arginine-rich splicing factor 2 0.379256
VCAM1 vascular cell adhesion molecule 1 0.378885
LCLAT1 lysocardiolipin acyltransferase 1 0.377402
ELAVL2 ELAV like neuron-specific RNA binding protein 2 0.37592
ADCK4 aarF domain containing kinase 4 0.37555
PYGB phosphorylase, glycogen; brain 0.37555
CAV1 caveolin 1, caveolae protein, 22kDa 0.374438
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.374438
SACS sacsin molecular chaperone 0.374438
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2 0.374068
LMOD1 leiomodin 1 (smooth muscle) 0.372587
PYGL phosphorylase, glycogen, liver 0.372217
PRAC1 prostate cancer susceptibility candidate 1 0.371847
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.371477
MAPT microtubule-associated protein tau 0.371477
MTO1 mitochondrial tRNA translation optimization 1 0.371107
GJC1 gap junction protein, gamma 1, 45kDa 0.370737
LIMS1 LIM and senescent cell antigen-like domains 1 0.369997
CELF2 CUGBP, Elav-like family member 2 0.368888
CD68 CD68 molecule 0.368149
PNPLA2 patatin-like phospholipase domain containing 2 0.366301
SLC2A12 solute carrier family 2 (facilitated glucose transporter), member 12 0.364085
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial 0.362978
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.360026
TFB2M transcription factor B2, mitochondrial 0.359657
HGS hepatocyte growth factor-regulated tyrosine kinase substrate 0.359289
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast) 0.355972
KNG1 kininogen 1 0.354499
CTSD cathepsin D 0.352659
TEAD2 TEA domain family member 2 0.349349
MYLK myosin light chain kinase 0.348246
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.347511
RHOJ ras homolog family member J 0.347511
PYGM phosphorylase, glycogen, muscle 0.346777
PPARG peroxisome proliferator-activated receptor gamma 0.346777
BTNL9 butyrophilin-like 9 0.344574
PRDX3 peroxiredoxin 3 0.344207
AGK acylglycerol kinase 0.343473
ACTN1 actinin, alpha 1 0.343473
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.339806
MURC muscle-related coiled-coil protein 0.339806
MRPS22 mitochondrial ribosomal protein S22 0.334681
CAT catalase 0.333949
CD34 CD34 molecule 0.332487
PIDD1 p53-induced death domain protein 1 0.332121
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase 0.331391
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.32993
XYLT1 xylosyltransferase I 0.329565
FRMPD1 FERM and PDZ domain containing 1 0.328834
HSPB7 heat shock 27kDa protein family, member 7 (cardiovascular) 0.326281
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta 0.32373
FUT2 fucosyltransferase 2 (secretor status included) 0.321545
POMT2 protein-O-mannosyltransferase 2 0.32009
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.319726
PDE4DIP phosphodiesterase 4D interacting protein 0.318635
FKTN fukutin 0.318635
APEX2 APEX nuclease (apurinic/apyrimidinic endonuclease) 2 0.317182
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.316456
RRM2 ribonucleotide reductase M2 0.315003
ACTB actin, beta 0.31464
DPP6 dipeptidyl-peptidase 6 0.313915
COQ9 coenzyme Q9 0.308842
ESRRG estrogen-related receptor gamma 0.305948
MIR146A microRNA 146a 0.304503
WASH7P WAS protein family homolog 7 pseudogene 0.304142
KIAA0101 KIAA0101 0.304142
MAP2K2 mitogen-activated protein kinase kinase 2 0.303781
WASH1 WAS protein family homolog 1 0.300533
MAP2K1 mitogen-activated protein kinase kinase 1 0.299812
CALR calreticulin 0.299092
IGLV2-8 immunoglobulin lambda variable 2-8 0.298371
WASH6P WAS protein family homolog 6 pseudogene 0.298011
AVP arginine vasopressin 0.297291
HFE hemochromatosis 0.296571
TFB1M transcription factor B1, mitochondrial 0.296211
FBN1 fibrillin 1 0.294772
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.294053
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.294053
LAMB4 laminin, beta 4 0.292975
HDLBP high density lipoprotein binding protein 0.292257
NPPC natriuretic peptide C 0.291539
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.290462
CPLX4 complexin 4 0.290103
SIRT1 sirtuin 1 0.290103
TMOD2 tropomodulin 2 (neuronal) 0.286519
GLS glutaminase 0.285802
DMPK dystrophia myotonica-protein kinase 0.285802
ACTG1 actin gamma 1 0.285802
MAPK14 mitogen-activated protein kinase 14 0.285086
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.283655
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 0.283297
HSPA8 heat shock 70kDa protein 8 0.282582
FPGT fucose-1-phosphate guanylyltransferase 0.282225
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.280439
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) 0.280082
GPR50 G protein-coupled receptor 50 0.279367
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A 0.278654
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5 0.27794
SYNE1 spectrin repeat containing, nuclear envelope 1 0.277227
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.276514
OBSL1 obscurin-like 1 0.276158
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 0.275801
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.274732
ATG14 autophagy related 14 0.271886
LPGAT1 lysophosphatidylglycerol acyltransferase 1 0.270464
ALG12 ALG12, alpha-1,6-mannosyltransferase 0.269753
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.268687
IGLV5-48 immunoglobulin lambda variable 5-48 (non-functional) 0.268687
ACAD9 acyl-CoA dehydrogenase family, member 9 0.266913
KCNH1 potassium channel, voltage gated eag related subfamily H, member 1 0.265494
RNASEH2A ribonuclease H2, subunit A 0.264785
TBX5 T-box 5 0.264785
CSRP2 cysteine and glycine-rich protein 2 0.263368
CTSL cathepsin L 0.263014
CLK1 CDC-like kinase 1 0.26266
GZMM granzyme M (lymphocyte met-ase 1) 0.262306
COQ6 coenzyme Q6 monooxygenase 0.260891
CTGF connective tissue growth factor 0.260184
FASLG Fas ligand (TNF superfamily, member 6) 0.255946
VEGFA vascular endothelial growth factor A 0.255241
CKM creatine kinase, muscle 0.251718
UCN2 urocortin 2 0.251366
PER3 period circadian clock 3 0.250663
RRAGB Ras-related GTP binding B 0.249608
IMMT inner membrane protein, mitochondrial 0.249608
IRX5 iroquois homeobox 5 0.248905
EOMES eomesodermin 0.248203
TXNRD2 thioredoxin reductase 2 0.247501
MOGAT1 monoacylglycerol O-acyltransferase 1 0.245046
B3GAT1 beta-1,3-glucuronyltransferase 1 0.244345
GLS2 glutaminase 2 (liver, mitochondrial) 0.243995
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.243295
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.242595
UBE2G1 ubiquitin-conjugating enzyme E2G 1 0.241196
RANBP17 RAN binding protein 17 0.241196
IVD isovaleryl-CoA dehydrogenase 0.239799
TXN thioredoxin 0.238403
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like 0.238054
CMC4 C-x(9)-C motif containing 4 0.237706
IL17A interleukin 17A 0.237357
COL1A1 collagen, type I, alpha 1 0.234225
PHC1 polyhomeotic homolog 1 (Drosophila) 0.23353
IGLV1-50 immunoglobulin lambda variable 1-50 (non-functional) 0.23353
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.232836
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.232489
GSK3B glycogen synthase kinase 3 beta 0.230755
PNMA2 paraneoplastic Ma antigen 2 0.22937
ADRA1D adrenoceptor alpha 1D 0.228679
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.228679
NRG1 neuregulin 1 0.228333
YIPF1 Yip1 domain family, member 1 0.228333
MME membrane metallo-endopeptidase 0.228333
ISM1 isthmin 1, angiogenesis inhibitor 0.227642
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 0.227642
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.227297
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.226262
MMP13 matrix metallopeptidase 13 0.225229
COX17 COX17 cytochrome c oxidase copper chaperone 0.224884
ANXA5 annexin A5 0.224196
NOTCH1 notch 1 0.223853
BECN1 beclin 1, autophagy related 0.222479
MPI mannose phosphate isomerase 0.222136
PLAC8 placenta-specific 8 0.222136
VWF von Willebrand factor 0.21974
ADRBK1 adrenergic, beta, receptor kinase 1 0.219057
LATS2 large tumor suppressor kinase 2 0.219057
RNASE3 ribonuclease, RNase A family, 3 0.218374
HBD hemoglobin, delta 0.218034
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.217693
CXCL12 chemokine (C-X-C motif) ligand 12 0.217352
IRX4 iroquois homeobox 4 0.216672
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.216332
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.215653
UNC5D unc-5 homolog D (C. elegans) 0.215314
RCE1 Ras converting CAAX endopeptidase 1 0.214636
LCK LCK proto-oncogene, Src family tyrosine kinase 0.211597
TBCD tubulin folding cofactor D 0.210925
ZYX zyxin 0.210925
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit 0.208245
IGFBP3 insulin-like growth factor binding protein 3 0.207578
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.207245
HOPX HOP homeobox 0.20658
F2 coagulation factor II (thrombin) 0.205585
IL2 interleukin 2 0.205254
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.204593
FGF16 fibroblast growth factor 16 0.202946
SIRPA signal-regulatory protein alpha 0.202946
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.202618
SDHAF1 succinate dehydrogenase complex assembly factor 1 0.201962
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.200331
PRKCA protein kinase C, alpha 0.200331
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.195183
TMOD1 tropomodulin 1 0.194548
PTRF polymerase I and transcript release factor 0.194548
GDF15 growth differentiation factor 15 0.193285
IPO5 importin 5 0.192971
KCNE5 potassium channel, voltage gated subfamily E regulatory beta subunit 5 0.192344
BCL2L1 BCL2-like 1 0.190786
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.190786
THBS4 thrombospondin 4 0.190168
NMS neuromedin S 0.189859
RRM1 ribonucleotide reductase M1 0.189551
RTN4 reticulon 4 0.189244
STRN striatin, calmodulin binding protein 0.189244
COL1A2 collagen, type I, alpha 2 0.188022
B2M beta-2-microglobulin 0.18591
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.185612
IGHMBP2 immunoglobulin mu binding protein 2 0.184128
HDAC2 histone deacetylase 2 0.180937
IGLV2-14 immunoglobulin lambda variable 2-14 0.180652
LMNB1 lamin B1 0.180652
PDCD1 programmed cell death 1 0.179802
ERBB2 erb-b2 receptor tyrosine kinase 2 0.178682
MKL1 megakaryoblastic leukemia (translocation) 1 0.178403
EFS embryonal Fyn-associated substrate 0.178403
ALPPL2 alkaline phosphatase, placental-like 2 0.177029
ALPP alkaline phosphatase, placental 0.176757
ALPL alkaline phosphatase, liver/bone/kidney 0.176215
TMPO thymopoietin 0.175146
ECE1 endothelin converting enzyme 1 0.174881
EDN2 endothelin 2 0.174617
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 0.173832
NCOA6 nuclear receptor coactivator 6 0.173571
DYSF dysferlin 0.172291
AK7 adenylate kinase 7 0.171785
CD70 CD70 molecule 0.170299
MSTN myostatin 0.169812
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) 0.168617
NOXA1 NADPH oxidase activator 1 0.168381
RANGRF RAN guanine nucleotide release factor 0.168381
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.168148
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.167224
FTMT ferritin mitochondrial 0.166768
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1 0.166544
MFN1 mitofusin 1 0.165217
MYL6 myosin, light chain 6, alkali, smooth muscle and non-muscle 0.165217
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.164786
SDS serine dehydratase 0.164786
PRB2 proline-rich protein BstNI subfamily 2 0.163938
RANBP3 RAN binding protein 3 0.162908
OR5K2 olfactory receptor, family 5, subfamily K, member 2 0.161912
PTMS parathymosin 0.161912
CTRL chymotrypsin-like 0.161523
TPM2 tropomyosin 2 (beta) 0.161331
FOXRED1 FAD-dependent oxidoreductase domain containing 1 0.160574
CD58 CD58 molecule 0.160021
LBR lamin B receptor 0.159658
MFAP5 microfibrillar associated protein 5 0.159658
PCMT1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 0.159124
RAB10 RAB10, member RAS oncogene family 0.158097
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 0.157929
MAPK8 mitogen-activated protein kinase 8 0.157929
VPREB1 pre-B lymphocyte 1 0.157765
SCX scleraxis basic helix-loop-helix transcription factor 0.143855
EPX eosinophil peroxidase 0.143832
IL5 interleukin 5 0.143474
FGF9 fibroblast growth factor 9 0.142686
IDS iduronate 2-sulfatase 0.142057
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.141354
ETV6 ets variant 6 0.141189
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.140659
FMN2 formin 2 0.14026
TNNC1 troponin C type 1 (slow) 0.140003
MYL9 myosin, light chain 9, regulatory 0.138298
HBB hemoglobin, beta 0.137731
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.137053
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.136965
HMX2 H6 family homeobox 2 0.136833
MYBPH myosin binding protein H 0.136587
TRAPPC9 trafficking protein particle complex 9 0.136403
FKBP1B FK506 binding protein 1B, 12.6 kDa 0.136281
RPS15A ribosomal protein S15a 0.136083
ZSCAN1 zinc finger and SCAN domain containing 1 0.135358
TGFB3 transforming growth factor, beta 3 0.135038
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.134514
MYO1C myosin IC 0.134441
TNNT1 troponin T type 1 (skeletal, slow) 0.134227
MRGPRE MAS-related GPR, member E 0.134093
MZF1 myeloid zinc finger 1 0.133571
DTNB dystrobrevin, beta 0.133562
DIO3 deiodinase, iodothyronine, type III 0.133407
TNNI2 troponin I type 2 (skeletal, fast) 0.132747
RYR3 ryanodine receptor 3 0.132479
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 0.132265
PRL prolactin 0.132225
INADL InaD-like (Drosophila) 0.131497
SLN sarcolipin 0.131102
TNNT3 troponin T type 3 (skeletal, fast) 0.131022
CCR7 chemokine (C-C motif) receptor 7 0.130823
MYO1E myosin IE 0.130693
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.130439
APCS amyloid P component, serum 0.130029
MUT methylmalonyl CoA mutase 0.129952
MYO15A myosin XVA 0.129927
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.129456
AK6 adenylate kinase 6 0.129091
CCNE2 cyclin E2 0.127957
IRAK1 interleukin-1 receptor-associated kinase 1 0.127514
TMPRSS15 transmembrane protease, serine 15 0.127248
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.126464
OPCML opioid binding protein/cell adhesion molecule-like 0.125743
FMN1 formin 1 0.125222
F13B coagulation factor XIII, B polypeptide 0.124835
CDK11A cyclin-dependent kinase 11A 0.124379
NTM neurotrimin 0.12359
HMOX2 heme oxygenase 2 0.121716
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 0.121671
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.121356
RPSA ribosomal protein SA 0.121241
PTPRD protein tyrosine phosphatase, receptor type, D 0.120962
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.120846
GREM2 gremlin 2, DAN family BMP antagonist 0.120776
LIG3 ligase III, DNA, ATP-dependent 0.119761
PVR poliovirus receptor 0.119463
NID1 nidogen 1 0.119339
DRD2 dopamine receptor D2 0.119006
PITX1 paired-like homeodomain 1 0.118066
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial 0.117771
EXTL3 exostosin-like glycosyltransferase 3 0.117716
WDFY2 WD repeat and FYVE domain containing 2 0.117415
COX11 COX11 cytochrome c oxidase copper chaperone 0.117251
ITGA8 integrin, alpha 8 0.116945
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.116352
TK2 thymidine kinase 2, mitochondrial 0.115945
ARRB1 arrestin, beta 1 0.115741
GAN gigaxonin 0.115567
TMOD4 tropomodulin 4 (muscle) 0.115567
INA internexin neuronal intermediate filament protein, alpha 0.115567
RING1 ring finger protein 1 0.115508
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.114636
FLNC filamin C, gamma 0.114605
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.11448
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 0.11448
LEF1 lymphoid enhancer-binding factor 1 0.114387
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.114387
TP63 tumor protein p63 0.114046
TFEB transcription factor EB 0.11383
PUS1 pseudouridylate synthase 1 0.112245
THUMPD1 THUMP domain containing 1 0.112113
FGD1 FYVE, RhoGEF and PH domain containing 1 0.111845
STRADA STE20-related kinase adaptor alpha 0.111472
SAA2 serum amyloid A2 0.111269
MAP2K7 mitogen-activated protein kinase kinase 7 0.110961
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.110507
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.110473
TES testin LIM domain protein 0.110403
AKAP9 A kinase (PRKA) anchor protein 9 0.110298
SLC7A4 solute carrier family 7, member 4 0.110193
PFDN4 prefoldin subunit 4 0.110159
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 0.109945
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2 0.109802
MUC4 mucin 4, cell surface associated 0.109371
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.109156
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.108862
SNTA1 syntrophin, alpha 1 0.108862
GYG1 glycogenin 1 0.108825
PSEN2 presenilin 2 0.108161
RPS6 ribosomal protein S6 0.107367
MEF2C myocyte enhancer factor 2C 0.106052
CD83 CD83 molecule 0.105576
PRODH proline dehydrogenase (oxidase) 1 0.105456
KLF11 Kruppel-like factor 11 0.105176
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.105176
RPS4Y1 ribosomal protein S4, Y-linked 1 0.104243
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.104037
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.103832
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.103791
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 0.10375
LAMA4 laminin, alpha 4 0.103669
SCN2B sodium channel, voltage gated, type II beta subunit 0.103543
IFNA13 interferon, alpha 13 0.103543
ASXL2 additional sex combs like transcriptional regulator 2 0.103374
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.103248
AK2 adenylate kinase 2 0.102912
SP8 Sp8 transcription factor 0.102702
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.102702
ESRRA estrogen-related receptor alpha 0.102576
CDX2 caudal type homeobox 2 0.102492
TLR3 toll-like receptor 3 0.102319
CLIC2 chloride intracellular channel 2 0.102276
ATP6AP1 ATPase, H+ transporting, lysosomal accessory protein 1 0.102233
TLR4 toll-like receptor 4 0.10219
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.101845
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.101845
CHURC1 churchill domain containing 1 0.101587
KRT9 keratin 9, type I 0.101458
DNASE1L3 deoxyribonuclease I-like 3 0.101372
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2) 0.101198
XYLT2 xylosyltransferase II 0.101109
HSPA4 heat shock 70kDa protein 4 0.101109
MDM4 MDM4, p53 regulator 0.101109
SRI sorcin 0.101109
THBS2 thrombospondin 2 0.101021
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.100933
CHD4 chromodomain helicase DNA binding protein 4 0.100933
RNF112 ring finger protein 112 0.100712
CCNI cyclin I 0.100712
IFNA2 interferon, alpha 2 0.100668
SAR1A secretion associated, Ras related GTPase 1A 0.100668
MFN2 mitofusin 2 0.100624
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 0.100536
EGLN3 egl-9 family hypoxia-inducible factor 3 0.10036
ACSL3 acyl-CoA synthetase long-chain family member 3 0.100316
KALRN kalirin, RhoGEF kinase 0.100272
RAP2B RAP2B, member of RAS oncogene family 0.100272
GYS1 glycogen synthase 1 (muscle) 0.100227
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.100006
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.099916
RAB1B RAB1B, member RAS oncogene family 0.099826
LOX lysyl oxidase 0.099735
HCCS holocytochrome c synthase 0.099735
PDGFC platelet derived growth factor C 0.099645
EIF4A2 eukaryotic translation initiation factor 4A2 0.099555
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 0.09951
CELF1 CUGBP, Elav-like family member 1 0.09951
F8 coagulation factor VIII, procoagulant component 0.09942
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.099194
SDPR serum deprivation response 0.099104
WAS Wiskott-Aldrich syndrome 0.099014
PLAT plasminogen activator, tissue 0.098879
STC1 stanniocalcin 1 0.09865
EXOC2 exocyst complex component 2 0.098327
ARF3 ADP-ribosylation factor 3 0.098281
NOS2 nitric oxide synthase 2, inducible 0.098281
SPEG SPEG complex locus 0.098143
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 0.098097
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.097866
APOC3 apolipoprotein C-III 0.097728
LAMB2 laminin, beta 2 (laminin S) 0.097636
COL3A1 collagen, type III, alpha 1 0.097544
HBEGF heparin-binding EGF-like growth factor 0.097356
USP9Y ubiquitin specific peptidase 9, Y-linked 0.097309
ESRP1 epithelial splicing regulatory protein 1 0.097262
LAMB1 laminin, beta 1 0.097168
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit 0.097026
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.097026
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 0.096979
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.096791
WDR5 WD repeat domain 5 0.096791
RBMY1A1 RNA binding motif protein, Y-linked, family 1, member A1 0.096791
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 0.096744
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.096509
MYOG myogenin (myogenic factor 4) 0.096273
HSF1 heat shock transcription factor 1 0.096131
USP5 ubiquitin specific peptidase 5 (isopeptidase T) 0.096131
IL12RB1 interleukin 12 receptor, beta 1 0.09589
HDAC3 histone deacetylase 3 0.09589
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.09589
PDLIM5 PDZ and LIM domain 5 0.095698
TSPO translocator protein (18kDa) 0.09565
PROM1 prominin 1 0.095554
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.095506
SMC1A structural maintenance of chromosomes 1A 0.095458
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.09541
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.095362
FBN2 fibrillin 2 0.095266