intrinsic apoptotic signaling pathway in response to oxidative stress Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered. (Gene Ontology, GO_0008631)
External Link http://amigo.geneontology.org/amigo/term/GO:0008631
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Genes

20 genes participating in the intrinsic apoptotic signaling pathway in response to oxidative stress biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
BCL2 B-cell CLL/lymphoma 2
CASP3 caspase 3, apoptosis-related cysteine peptidase
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DIABLO diablo, IAP-binding mitochondrial protein
GPX1 glutathione peroxidase 1
JAK2 Janus kinase 2
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MELK maternal embryonic leucine zipper kinase
PDCD10 programmed cell death 10
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PML promyelocytic leukemia
PRKCD protein kinase C, delta
PRODH proline dehydrogenase (oxidase) 1
RNF7 ring finger protein 7
SOD2 superoxide dismutase 2, mitochondrial
STK24 serine/threonine kinase 24
STK25 serine/threonine kinase 25
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
ZNF622 zinc finger protein 622