intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered. (Gene Ontology, GO_0042771)
External Link http://amigo.geneontology.org/amigo/term/GO:0042771
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Genes

29 genes participating in the intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AEN apoptosis enhancing nuclease
BAG6 BCL2-associated athanogene 6
BCL3 B-cell CLL/lymphoma 3
BRCA2 breast cancer 2, early onset
CDIP1 cell death-inducing p53 target 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT4 DNA-damage-inducible transcript 4
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EP300 E1A binding protein p300
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
IFI16 interferon, gamma-inducible protein 16
MSH2 mutS homolog 2
NUPR1 nuclear protein, transcriptional regulator, 1
PGAP2 post-GPI attachment to proteins 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PYCARD PYD and CARD domain containing
RPS27L ribosomal protein S27-like
SHISA5 shisa family member 5
SIRT1 sirtuin 1
SNW1 SNW domain containing 1
TMEM109 transmembrane protein 109
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
USP28 ubiquitin specific peptidase 28