intrinsic apoptotic signaling pathway by p53 class mediator Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered. (Gene Ontology, GO_0072332)
External Link http://amigo.geneontology.org/amigo/term/GO:0072332
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Genes

47 genes participating in the intrinsic apoptotic signaling pathway by p53 class mediator biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
AEN apoptosis enhancing nuclease
BAG6 BCL2-associated athanogene 6
BAX BCL2-associated X protein
BCL3 B-cell CLL/lymphoma 3
BOK BCL2-related ovarian killer
BRCA2 breast cancer 2, early onset
CDIP1 cell death-inducing p53 target 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT4 DNA-damage-inducible transcript 4
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
E2F1 E2F transcription factor 1
E2F2 E2F transcription factor 2
EDA2R ectodysplasin A2 receptor
EP300 E1A binding protein p300
FHIT fragile histidine triad
HINT1 histidine triad nucleotide binding protein 1
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
IFI16 interferon, gamma-inducible protein 16
JMY junction mediating and regulatory protein, p53 cofactor
MSH2 mutS homolog 2
MYBBP1A MYB binding protein (P160) 1a
NUPR1 nuclear protein, transcriptional regulator, 1
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PERP PERP, TP53 apoptosis effector
PGAP2 post-GPI attachment to proteins 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PYCARD PYD and CARD domain containing
RPS27L ribosomal protein S27-like
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
SHISA5 shisa family member 5
SIRT1 sirtuin 1
SNW1 SNW domain containing 1
STK11 serine/threonine kinase 11
TMEM109 transmembrane protein 109
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TP63 tumor protein p63
TP73 tumor protein p73
USP28 ubiquitin specific peptidase 28
WWOX WW domain containing oxidoreductase
ZNF385B zinc finger protein 385B