intestinal benign neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A gastrointestinal system benign neoplasm that is located_in the intestine. (Human Disease Ontology, DOID_4610)
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Genes

318 genes co-occuring with the disease intestinal benign neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
APOLD1 apolipoprotein L domain containing 1 1.71955
APC adenomatous polyposis coli 1.6525
DEFB106B defensin, beta 106B 1.11856
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.11645
ZIK1 zinc finger protein interacting with K protein 1 1.05177
MYO1A myosin IA 1.01343
KRT20 keratin 20, type I 1.00288
PRR15 proline rich 15 0.983479
SPRR2A small proline-rich protein 2A 0.964986
TEX30 testis expressed 30 0.927932
CCND1 cyclin D1 0.924213
TYMS thymidylate synthetase 0.909376
CDX2 caudal type homeobox 2 0.906498
KRT7 keratin 7, type II 0.859362
PLEKHO1 pleckstrin homology domain containing, family O member 1 0.856497
ODC1 ornithine decarboxylase 1 0.839296
CABLES1 Cdk5 and Abl enzyme substrate 1 0.831099
TP53 tumor protein p53 0.820026
DCLK1 doublecortin-like kinase 1 0.817976
MLH1 mutL homolog 1 0.817565
KRAS Kirsten rat sarcoma viral oncogene homolog 0.814283
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.801154
HNF4A hepatocyte nuclear factor 4, alpha 0.786803
UNC5C unc-5 homolog C (C. elegans) 0.773296
MUTYH mutY homolog 0.750457
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 0.748017
CCDC80 coiled-coil domain containing 80 0.739082
GRP gastrin-releasing peptide 0.711587
USP28 ubiquitin specific peptidase 28 0.698313
HLTF helicase-like transcription factor 0.695905
CCNO cyclin O 0.694702
PCNA proliferating cell nuclear antigen 0.694301
ZKSCAN3 zinc finger with KRAB and SCAN domains 3 0.692697
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.689092
SST somatostatin 0.675909
HRAS Harvey rat sarcoma viral oncogene homolog 0.665563
KCTD5 potassium channel tetramerization domain containing 5 0.660008
MSRB3 methionine sulfoxide reductase B3 0.659215
MUC2 mucin 2, oligomeric mucus/gel-forming 0.654858
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.653276
VASH2 vasohibin 2 0.652089
LEF1 lymphoid enhancer-binding factor 1 0.649323
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.633169
KIF18A kinesin family member 18A 0.626103
SPRR1A small proline-rich protein 1A 0.612401
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.59913
GLP2R glucagon-like peptide 2 receptor 0.587833
FABP1 fatty acid binding protein 1, liver 0.587444
GUCA2B guanylate cyclase activator 2B (uroguanylin) 0.586276
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.582384
ZNF135 zinc finger protein 135 0.579661
MSH2 mutS homolog 2 0.569163
MAPK3 mitogen-activated protein kinase 3 0.568775
MMP7 matrix metallopeptidase 7 0.561392
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.555568
AXIN1 axin 1 0.550522
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.548195
ENO2 enolase 2 (gamma, neuronal) 0.545093
CALD1 caldesmon 1 0.543542
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.530381
TFF3 trefoil factor 3 (intestinal) 0.52729
HPGDS hematopoietic prostaglandin D synthase 0.521888
PCSK1 proprotein convertase subtilisin/kexin type 1 0.521502
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.51919
VIP vasoactive intestinal peptide 0.51919
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.514571
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease 0.512264
KLF5 Kruppel-like factor 5 (intestinal) 0.509959
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.508808
BCO1 beta-carotene oxygenase 1 0.508041
BCL9L B-cell CLL/lymphoma 9-like 0.493122
PAOX polyamine oxidase (exo-N4-amino) 0.49274
SLC4A3 solute carrier family 4 (anion exchanger), member 3 0.487407
STC1 stanniocalcin 1 0.478668
PRTN3 proteinase 3 0.47753
SRPK1 SRSF protein kinase 1 0.471089
EFNA1 ephrin-A1 0.469954
EREG epiregulin 0.468819
CD44 CD44 molecule (Indian blood group) 0.468441
ST18 suppression of tumorigenicity 18, zinc finger 0.467684
PCSK5 proprotein convertase subtilisin/kexin type 5 0.465038
PMEPA1 prostate transmembrane protein, androgen induced 1 0.463905
BAK1 BCL2-antagonist/killer 1 0.458619
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 0.448817
SLC26A3 solute carrier family 26 (anion exchanger), member 3 0.439034
TIAM1 T-cell lymphoma invasion and metastasis 1 0.438282
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 0.435651
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.433772
INSM1 insulinoma-associated 1 0.427765
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.42214
GAST gastrin 0.42139
PROX1 prospero homeobox 1 0.415773
UNC5A unc-5 homolog A (C. elegans) 0.411657
CTNNA2 catenin (cadherin-associated protein), alpha 2 0.405305
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.402692
KLF10 Kruppel-like factor 10 0.401199
PPARG peroxisome proliferator-activated receptor gamma 0.397471
KLF4 Kruppel-like factor 4 (gut) 0.397098
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.391513
CSNK2B casein kinase 2, beta polypeptide 0.388909
CSN1S1 casein alpha s1 0.388166
HES3 hes family bHLH transcription factor 3 0.387051
IL17F interleukin 17F 0.386679
CD34 CD34 molecule 0.383708
CLDN1 claudin 1 0.37555
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.374438
MECOM MDS1 and EVI1 complex locus 0.372587
MYOF myoferlin 0.369628
CHGA chromogranin A 0.369258
NARS asparaginyl-tRNA synthetase 0.368888
NOTCH1 notch 1 0.364085
AXIN2 axin 2 0.363716
CLDN7 claudin 7 0.362239
PPAT phosphoribosyl pyrophosphate amidotransferase 0.36187
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.360764
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.357077
SMAD4 SMAD family member 4 0.356709
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.354131
GAN gigaxonin 0.353395
RAB25 RAB25, member RAS oncogene family 0.353027
BCL9 B-cell CLL/lymphoma 9 0.352659
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.351555
ETV4 ets variant 4 0.350452
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.341639
CES2 carboxylesterase 2 0.339806
SLC31A1 solute carrier family 31 (copper transporter), member 1 0.332852
SGK1 serum/glucocorticoid regulated kinase 1 0.331756
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.329565
NMU neuromedin U 0.316456
WNT1 wingless-type MMTV integration site family, member 1 0.315366
NTN1 netrin 1 0.313189
MYC v-myc avian myelocytomatosis viral oncogene homolog 0.30848
ZNF410 zinc finger protein 410 0.308118
MMP28 matrix metallopeptidase 28 0.305226
NBPF10 neuroblastoma breakpoint family, member 10 0.303781
PTGES2 prostaglandin E synthase 2 0.296571
JUN jun proto-oncogene 0.296211
LY6E lymphocyte antigen 6 complex, locus E 0.295851
ADGRE5 adhesion G protein-coupled receptor E5 0.293694
PPARD peroxisome proliferator-activated receptor delta 0.290462
NXN nucleoredoxin 0.289027
BMP5 bone morphogenetic protein 5 0.284013
SAMM50 SAMM50 sorting and assembly machinery component 0.282582
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.280439
MPO myeloperoxidase 0.279011
TDG thymine-DNA glycosylase 0.277227
SPN sialophorin 0.277227
SMC3 structural maintenance of chromosomes 3 0.275445
WNT5A wingless-type MMTV integration site family, member 5A 0.273308
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide 0.269753
PARD6A par-6 family cell polarity regulator alpha 0.263368
RETNLB resistin like beta 0.25983
THBS4 thrombospondin 4 0.259477
PDCD5 programmed cell death 5 0.258417
GSTA3 glutathione S-transferase alpha 3 0.256652
GSTM1 glutathione S-transferase mu 1 0.256299
GSTA2 glutathione S-transferase alpha 2 0.255594
NBPF8 neuroblastoma breakpoint family, member 8 0.255241
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.254888
GSTA4 glutathione S-transferase alpha 4 0.254536
WNT3A wingless-type MMTV integration site family, member 3A 0.249257
GSTA1 glutathione S-transferase alpha 1 0.248905
NOTCH2 notch 2 0.246799
MLNR motilin receptor 0.245046
ANPEP alanyl (membrane) aminopeptidase 0.244696
NOTCH2NL notch 2 N-terminal like 0.244345
PODXL podocalyxin-like 0.243995
PYCARD PYD and CARD domain containing 0.234225
SCRT1 scratch family zinc finger 1 0.232836
NTS neurotensin 0.231795
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.231448
PTGES prostaglandin E synthase 0.230755
LSR lipolysis stimulated lipoprotein receptor 0.230409
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.230409
LRG1 leucine-rich alpha-2-glycoprotein 1 0.227988
APAF1 apoptotic peptidase activating factor 1 0.225917
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.225229
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.221108
HCAR2 hydroxycarboxylic acid receptor 2 0.217352
NOS2 nitric oxide synthase 2, inducible 0.216332
PSAT1 phosphoserine aminotransferase 1 0.213621
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.211261
JAK3 Janus kinase 3 0.210589
TNF tumor necrosis factor 0.207245
MYRF myelin regulatory factor 0.205916
TGFBR1 transforming growth factor, beta receptor 1 0.203933
GCG glucagon 0.201308
TBCE tubulin folding cofactor E 0.201308
MIR19A microRNA 19a 0.200982
CLCN3 chloride channel, voltage-sensitive 3 0.200006
CNR2 cannabinoid receptor 2 (macrophage) 0.198709
MLN motilin 0.197742
BTC betacellulin 0.197099
GSTTP1 glutathione S-transferase theta pseudogene 1 0.195501
GSTT1 glutathione S-transferase theta 1 0.195183
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 0.194232
PDPK1 3-phosphoinositide dependent protein kinase 1 0.1936
AOX1 aldehyde oxidase 1 0.1936
MIR96 microRNA 96 0.193285
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.190476
CDX1 caudal type homeobox 1 0.189859
EGFR epidermal growth factor receptor 0.187113
DSC2 desmocollin 2 0.18591
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble 0.185612
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D 0.185612
NCAM1 neural cell adhesion molecule 1 0.185016
FLAD1 flavin adenine dinucleotide synthetase 1 0.18472
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.182375
OXT oxytocin/neurophysin I prepropeptide 0.177029
SOX17 SRY (sex determining region Y)-box 17 0.176757
CD5 CD5 molecule 0.174093
PEG10 paternally expressed 10 0.173057
NKX2-2 NK2 homeobox 2 0.170544
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.168854
EPCAM epithelial cell adhesion molecule 0.167682
IL23R interleukin 23 receptor 0.167452
XPA xeroderma pigmentosum, complementation group A 0.165655
CTSB cathepsin B 0.165655
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.165435
APLP1 amyloid beta (A4) precursor-like protein 1 0.165435
TSG101 tumor susceptibility 101 0.165001
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.161331
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.160761
KRT83 keratin 83, type II 0.160574
RORC RAR-related orphan receptor C 0.159124
NFIB nuclear factor I/B 0.14071
SYP synaptophysin 0.139535
TGM1 transglutaminase 1 0.139204
HMGA2 high mobility group AT-hook 2 0.137
IGHV1-2 immunoglobulin heavy variable 1-2 0.136275
TPH1 tryptophan hydroxylase 1 0.134003
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.132911
MUC6 mucin 6, oligomeric mucus/gel-forming 0.13074
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.124665
MAPK8 mitogen-activated protein kinase 8 0.124097
MUC1 mucin 1, cell surface associated 0.123264
SETD1A SET domain containing 1A 0.121413
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.119488
RHCE Rh blood group, CcEe antigens 0.118839
BCL2 B-cell CLL/lymphoma 2 0.118357
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.117933
MIR31 microRNA 31 0.116338
MTDH metadherin 0.115843
IARS isoleucyl-tRNA synthetase 0.115072
RHD Rh blood group, D antigen 0.114139
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.112278
CD79A CD79a molecule, immunoglobulin-associated alpha 0.109802
GPNMB glycoprotein (transmembrane) nmb 0.095963
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase 0.095074
YARS tyrosyl-tRNA synthetase 0.094515
POMC proopiomelanocortin 0.093682
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide 0.093111
CCK cholecystokinin 0.092413
PIGF phosphatidylinositol glycan anchor biosynthesis, class F 0.092012
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.091961
DPYD dihydropyrimidine dehydrogenase 0.091885
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.09186
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.091809
RECK reversion-inducing-cysteine-rich protein with kazal motifs 0.091555
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.091428
HMOX2 heme oxygenase 2 0.087374
OMG oligodendrocyte myelin glycoprotein 0.087374
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 0.087268
NCOA1 nuclear receptor coactivator 1 0.087188
GFAP glial fibrillary acidic protein 0.086868
LDHB lactate dehydrogenase B 0.086255
CRX cone-rod homeobox 0.086174
LIG1 ligase I, DNA, ATP-dependent 0.085714
IL1R1 interleukin 1 receptor, type I 0.085497
TFF2 trefoil factor 2 0.084384
CXCL8 chemokine (C-X-C motif) ligand 8 0.084274
WNT2 wingless-type MMTV integration site family member 2 0.083316
ACTA1 actin, alpha 1, skeletal muscle 0.082622
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.0824
POR P450 (cytochrome) oxidoreductase 0.082206
PER3 period circadian clock 3 0.081984
ALOX5 arachidonate 5-lipoxygenase 0.081957
ALPI alkaline phosphatase, intestinal 0.081623
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.081258
MALT1 MALT1 paracaspase 0.081258
TJP1 tight junction protein 1 0.081061
GSTP1 glutathione S-transferase pi 1 0.080276
NMT1 N-myristoyltransferase 1 0.079994
CDSN corneodesmosin 0.079966
KLK7 kallikrein-related peptidase 7 0.079228
FEN1 flap structure-specific endonuclease 1 0.079115
B3GAT1 beta-1,3-glucuronyltransferase 1 0.078775
AREG amphiregulin 0.078204
CDKN2A cyclin-dependent kinase inhibitor 2A 0.076829
ITGA6 integrin, alpha 6 0.075357
KLK3 kallikrein-related peptidase 3 0.075124
APRT adenine phosphoribosyltransferase 0.074862
MICA MHC class I polypeptide-related sequence A 0.074629
ELAVL1 ELAV like RNA binding protein 1 0.074629
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.074454
SOD2 superoxide dismutase 2, mitochondrial 0.074309
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.074193
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 0.073728
IGF2R insulin-like growth factor 2 receptor 0.073141
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.072849
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.072702
RDX radixin 0.072556
IFNB1 interferon, beta 1, fibroblast 0.072468
PTN pleiotrophin 0.072058
TLR5 toll-like receptor 5 0.07197
E2F3 E2F transcription factor 3 0.071911
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.071174
MIR145 microRNA 145 0.071027
PTEN phosphatase and tensin homolog 0.07088
TGFB1 transforming growth factor, beta 1 0.069699
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.069551
PMEL premelanosome protein 0.069373
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.068989
MAPK1 mitogen-activated protein kinase 1 0.068989
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.06893
FST follistatin 0.068723
MSN moesin 0.068277
GPX1 glutathione peroxidase 1 0.068277