interstitial cystitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

159 genes co-occuring with the disease interstitial cystitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
NME1-NME2 NME1-NME2 readthrough 2.0225
NME2 NME/NM23 nucleoside diphosphate kinase 2 1.93374
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3 1.74051
TSPO translocator protein (18kDa) 1.67955
CKAP4 cytoskeleton-associated protein 4 1.64218
FZD8 frizzled class receptor 8 1.61217
HBEGF heparin-binding EGF-like growth factor 1.61039
NGF nerve growth factor (beta polypeptide) 1.55424
TAC1 tachykinin, precursor 1 1.52248
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 1.44298
ZDHHC2 zinc finger, DHHC-type containing 2 1.23863
UPK3A uroplakin 3A 1.22475
TRPV1 transient receptor potential cation channel, subfamily V, member 1 1.19359
SPRR2G small proline-rich protein 2G 1.17164
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 1.14517
UPK2 uroplakin 2 0.928759
NPS neuropeptide S 0.920911
TJP1 tight junction protein 1 0.890078
HRH1 histamine receptor H1 0.885569
CRH corticotropin releasing hormone 0.88434
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic) 0.879014
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 0.876966
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 0.872462
TACR1 tachykinin receptor 1 0.869596
CMA1 chymase 1, mast cell 0.862637
SYNRG synergin, gamma 0.829459
BNC1 basonuclin 1 0.825768
MSRB2 methionine sulfoxide reductase B2 0.824538
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 0.822488
NCAM2 neural cell adhesion molecule 2 0.820847
GBP5 guanylate binding protein 5 0.819616
XPOT exportin, tRNA 0.784345
MSRB3 methionine sulfoxide reductase B3 0.770435
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 0.735838
KNG1 kininogen 1 0.712392
MT1B metallothionein 1B 0.699919
HAVCR2 hepatitis A virus cellular receptor 2 0.685891
GJC1 gap junction protein, gamma 1, 45kDa 0.672722
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.671527
ANO2 anoctamin 2, calcium activated chloride channel 0.654463
UPK1B uroplakin 1B 0.642615
CGN cingulin 0.642221
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.635528
GBP2 guanylate binding protein 2, interferon-inducible 0.626495
GSPT1 G1 to S phase transition 1 0.625711
PSIP1 PC4 and SFRS1 interacting protein 1 0.617877
HRH2 histamine receptor H2 0.616312
SPAG11A sperm associated antigen 11A 0.613574
IL6 interleukin 6 0.612401
RNASE3 ribonuclease, RNase A family, 3 0.607714
GSTM5 glutathione S-transferase mu 5 0.595233
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.583552
SPAG11B sperm associated antigen 11B 0.577327
UPK1A uroplakin 1A 0.57655
CRHR2 corticotropin releasing hormone receptor 2 0.574217
CATSPER1 cation channel, sperm associated 1 0.554791
KLK4 kallikrein-related peptidase 4 0.552463
MT1F metallothionein 1F 0.550911
SIVA1 SIVA1, apoptosis-inducing factor 0.545093
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.538893
CALCA calcitonin-related polypeptide alpha 0.530381
OCLN occludin 0.521502
P2RY11 purinergic receptor P2Y, G-protein coupled, 11 0.516494
PPAN-P2RY11 PPAN-P2RY11 readthrough 0.516494
IFI44L interferon-induced protein 44-like 0.513033
MKNK1 MAP kinase interacting serine/threonine kinase 1 0.504207
TYMP thymidine phosphorylase 0.501527
IL17RB interleukin 17 receptor B 0.488549
MT1X metallothionein 1X 0.480186
MT1E metallothionein 1E 0.479807
HSF2 heat shock transcription factor 2 0.47753
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.465416
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.432646
CCR2 chemokine (C-C motif) receptor 2 0.43227
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.426265
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.420266
KDM6B lysine (K)-specific demethylase 6B 0.417644
MN1 meningioma (disrupted in balanced translocation) 1 0.413153
GJA1 gap junction protein, alpha 1, 43kDa 0.412405
OSGEP O-sialoglycoprotein endopeptidase 0.408666
MT1A metallothionein 1A 0.405305
UCN3 urocortin 3 0.404931
UBD ubiquitin D 0.403064
ADRB2 adrenoceptor beta 2, surface 0.400826
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.396353
FOS FBJ murine osteosarcoma viral oncogene homolog 0.395608
GBP1 guanylate binding protein 1, interferon-inducible 0.394118
MT1G metallothionein 1G 0.393001
PENK proenkephalin 0.391885
COIL coilin 0.378885
LGALS7B lectin, galactoside-binding, soluble, 7B 0.377402
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.376661
TNF tumor necrosis factor 0.37592
ORM1 orosomucoid 1 0.374809
UCN urocortin 0.369997
ITGA1 integrin, alpha 1 0.366671
PDYN prodynorphin 0.362239
UMOD uromodulin 0.355604
CXCL9 chemokine (C-X-C motif) ligand 9 0.352291
RENBP renin binding protein 0.350084
BDNF brain-derived neurotrophic factor 0.344574
TAGLN transgelin 0.339806
LRP4 low density lipoprotein receptor-related protein 4 0.339073
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.337608
PTGFR prostaglandin F receptor (FP) 0.334315
CRHR1 corticotropin releasing hormone receptor 1 0.333218
SCN9A sodium channel, voltage gated, type IX alpha subunit 0.331756
TES testin LIM domain protein 0.32701
CLCN6 chloride channel, voltage-sensitive 6 0.326281
CXCR3 chemokine (C-X-C motif) receptor 3 0.324094
MUC7 mucin 7, secreted 0.324094
KLK1 kallikrein 1 0.311014
CRAT carnitine O-acetyltransferase 0.307395
P2RY2 purinergic receptor P2Y, G-protein coupled, 2 0.302698
BCAN brevican 0.294772
SUFU suppressor of fused homolog (Drosophila) 0.280796
AKR1C2 aldo-keto reductase family 1, member C2 0.280796
HVCN1 hydrogen voltage gated channel 1 0.279724
HM13 histocompatibility (minor) 13 0.279724
EGR3 early growth response 3 0.273664
EYA1 EYA transcriptional coactivator and phosphatase 1 0.271886
SDC1 syndecan 1 0.270108
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.257358
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4 0.253479
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.251015
ASIC1 acid sensing (proton gated) ion channel 1 0.247852
IRF6 interferon regulatory factor 6 0.246799
KITLG KIT ligand 0.245396
TACR2 tachykinin receptor 2 0.242245
CYSLTR1 cysteinyl leukotriene receptor 1 0.241546
DCN decorin 0.236312
CCL2 chemokine (C-C motif) ligand 2 0.234225
HRH4 histamine receptor H4 0.23353
IRGM immunity-related GTPase family, M 0.228679
HLA-E major histocompatibility complex, class I, E 0.214975
REG3A regenerating islet-derived 3 alpha 0.209248
NKX2-5 NK2 homeobox 5 0.206913
SNAP23 synaptosomal-associated protein, 23kDa 0.197099
CNN1 calponin 1, basic, smooth muscle 0.19582
FGR FGR proto-oncogene, Src family tyrosine kinase 0.183835
FGF10 fibroblast growth factor 10 0.18151
CSN3 casein kappa 0.180367
PNPLA2 patatin-like phospholipase domain containing 2 0.176485
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.175947
LHCGR luteinizing hormone/choriogonadotropin receptor 0.174881
NSF N-ethylmaleimide-sensitive factor 0.174617
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.174354
NOVA2 neuro-oncological ventral antigen 2 0.172291
TFF2 trefoil factor 2 0.172038
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.170544
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.16933
MUC1 mucin 1, cell surface associated 0.167452
CXCL10 chemokine (C-X-C motif) ligand 10 0.165217
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8 0.165001
BAX BCL2-associated X protein 0.164571
IGFBP3 insulin-like growth factor binding protein 3 0.162505
NLE1 notchless homolog 1 (Drosophila) 0.162505
MIXL1 Mix paired-like homeobox 0.161331
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.157765