interleukin-27 complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space. (Gene Ontology, GO_0070744)
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Genes

143 proteins co-occuring with the interleukin-27 complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
EBI3 Epstein-Barr virus induced 3 3.15705
IL27 interleukin 27 2.84339
IL27RA interleukin 27 receptor, alpha 2.35689
CENPV centromere protein V 1.535
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 1.36088
FOXP3 forkhead box P3 1.30873
FAM192A family with sequence similarity 192, member A 1.18748
CNTN1 contactin 1 1.12756
TBX21 T-box 21 1.12552
PLVAP plasmalemma vesicle associated protein 1.04934
CD4 CD4 molecule 1.03679
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 1.01238
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 0.940215
RORC RAR-related orphan receptor C 0.930774
TACSTD2 tumor-associated calcium signal transducer 2 0.919982
PILRB paired immunoglobin-like type 2 receptor beta 0.904602
NPTN neuroplastin 0.846532
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.734217
IL18BP interleukin 18 binding protein 0.709251
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.703949
TTC29 tetratricopeptide repeat domain 29 0.698223
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase 0.678108
MIEN1 migration and invasion enhancer 1 0.658619
GATA3 GATA binding protein 3 0.650869
PLP1 proteolipid protein 1 0.629039
TPPP tubulin polymerization promoting protein 0.627761
IL2RB interleukin 2 receptor, beta 0.626909
IL23A interleukin 23, alpha subunit p19 0.625206
TP53 tumor protein p53 0.62393
PDPN podoplanin 0.610778
IL2RG interleukin 2 receptor, gamma 0.610355
STAT1 signal transducer and activator of transcription 1, 91kDa 0.604017
TARS threonyl-tRNA synthetase 0.568416
ZNF79 zinc finger protein 79 0.560528
TMEM53 transmembrane protein 53 0.550186
ANK1 ankyrin 1, erythrocytic 0.546885
EVPL envoplakin 0.543587
CACNA2D4 calcium channel, voltage-dependent, alpha 2/delta subunit 4 0.532078
ANO7P1 anoctamin 7 pseudogene 1 0.517348
PLAC1 placenta-specific 1 0.515716
TLR4 toll-like receptor 4 0.515716
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 0.510418
ZNF185 zinc finger protein 185 (LIM domain) 0.507163
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.495395
DNALI1 dynein, axonemal, light intermediate chain 1 0.488115
CKLF chemokine-like factor 0.487307
IFT74 intraflagellar transport 74 0.485289
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 0.482467
FOXQ1 forkhead box Q1 0.478843
IL6R interleukin 6 receptor 0.476831
DNASE2B deoxyribonuclease II beta 0.474018
CXCL11 chemokine (C-X-C motif) ligand 11 0.473617
PAAF1 proteasomal ATPase-associated factor 1 0.470807
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.470005
CCL16 chemokine (C-C motif) ligand 16 0.466399
IL12RB1 interleukin 12 receptor, beta 1 0.453223
IRF1 interferon regulatory factor 1 0.453223
TMED2 transmembrane emp24 domain trafficking protein 2 0.439728
CCL22 chemokine (C-C motif) ligand 22 0.433012
IL12RB2 interleukin 12 receptor, beta 2 0.429072
CXCL16 chemokine (C-X-C motif) ligand 16 0.428678
EIF4E eukaryotic translation initiation factor 4E 0.41182
MYD88 myeloid differentiation primary response 88 0.409089
IL12B interleukin 12B 0.400916
RHOBTB2 Rho-related BTB domain containing 2 0.392001
GSTO1 glutathione S-transferase omega 1 0.388909
IFI35 interferon-induced protein 35 0.383124
EIF3K eukaryotic translation initiation factor 3, subunit K 0.377738
TLR3 toll-like receptor 3 0.375434
ELSPBP1 epididymal sperm binding protein 1 0.371599
IMMT inner membrane protein, mitochondrial 0.368919
BCL6 B-cell CLL/lymphoma 6 0.361659
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14 0.360133
C5AR2 complement component 5a receptor 2 0.358228
LGALS13 lectin, galactoside-binding, soluble, 13 0.352522
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.339261
WDR19 WD repeat domain 19 0.337751
IL6ST interleukin 6 signal transducer 0.337751
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.333225
BIRC7 baculoviral IAP repeat containing 7 0.332095
CMKLR1 chemerin chemokine-like receptor 1 0.324951
CD83 CD83 molecule 0.320451
CRLF1 cytokine receptor-like factor 1 0.319702
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.316334
CD274 CD274 molecule 0.310358
IFNA1 interferon, alpha 1 0.308867
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C 0.302912
CDKN2A cyclin-dependent kinase inhibitor 2A 0.302912
PNMA2 paraneoplastic Ma antigen 2 0.30254
GZMH granzyme H (cathepsin G-like 2, protein h-CCPX) 0.301797
PLBD2 phospholipase B domain containing 2 0.300682
RPL8 ribosomal protein L8 0.297713
FABP2 fatty acid binding protein 2, intestinal 0.293637
CXCR3 chemokine (C-X-C motif) receptor 3 0.291047
WWP1 WW domain containing E3 ubiquitin protein ligase 1 0.287352
CXCL3 chemokine (C-X-C motif) ligand 3 0.285138
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.275202
CCL1 chemokine (C-C motif) ligand 1 0.272267
ELOVL4 ELOVL fatty acid elongase 4 0.271533
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.2708
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.268969
TYK2 tyrosine kinase 2 0.268603
HYLS1 hydrolethalus syndrome 1 0.266042
CNGA3 cyclic nucleotide gated channel alpha 3 0.262755
LGALS9 lectin, galactoside-binding, soluble, 9 0.26166
CXCL10 chemokine (C-X-C motif) ligand 10 0.26166
HPCA hippocalcin 0.26166
TREX1 three prime repair exonuclease 1 0.260202
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A 0.259837
LAMP3 lysosomal-associated membrane protein 3 0.259109
CCL13 chemokine (C-C motif) ligand 13 0.256561
IFT172 intraflagellar transport 172 0.247854
IFNG interferon, gamma 0.245323
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.243519
FOXP1 forkhead box P1 0.239197
IRF8 interferon regulatory factor 8 0.23776
STRBP spermatid perinuclear RNA binding protein 0.234891
LAG3 lymphocyte-activation gene 3 0.233101
ERVW-1 endogenous retrovirus group W, member 1 0.232386
CST7 cystatin F (leukocystatin) 0.228464
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.21681
CXCR6 chemokine (C-X-C motif) receptor 6 0.215412
CD163 CD163 molecule 0.210894
CXCL9 chemokine (C-X-C motif) ligand 9 0.209169
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.208825
MOG myelin oligodendrocyte glycoprotein 0.207794
CBLN1 cerebellin 1 precursor 0.206423
CNTFR ciliary neurotrophic factor receptor 0.20574
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.202346
CDK2 cyclin-dependent kinase 2 0.201672
SYNPR synaptoporin 0.200328
MAPK1 mitogen-activated protein kinase 1 0.194045
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.192746
TXNL1 thioredoxin-like 1 0.184853
SOCS3 suppressor of cytokine signaling 3 0.173814
CCR7 chemokine (C-C motif) receptor 7 0.170629
SH2D3A SH2 domain containing 3A 0.168847
C3 complement component 3 0.167611
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 0.167611
CNTF ciliary neurotrophic factor 0.164315
SP100 SP100 nuclear antigen 0.160254
CXCR5 chemokine (C-X-C motif) receptor 5 0.158882
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.158315