interchromatin granule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs). (Gene Ontology, GO_0035061)
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Genes

72 proteins co-occuring with the interchromatin granule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SRSF2 serine/arginine-rich splicing factor 2 2.12967
COIL coilin 1.45986
CBS cystathionine-beta-synthase 1.18184
TPH2 tryptophan hydroxylase 2 1.1245
ABT1 activator of basal transcription 1 1.03279
NXF1 nuclear RNA export factor 1 1.01486
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.94876
GGNBP1 gametogenetin binding protein 1 (pseudogene) 0.919982
TUG1 taurine up-regulated 1 (non-protein coding) 0.903673
KDM1A lysine (K)-specific demethylase 1A 0.878251
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like 0.807982
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.735115
CCNC cyclin C 0.725258
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3 0.723919
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) 0.674196
ATE1 arginyltransferase 1 0.671593
CDK8 cyclin-dependent kinase 8 0.630745
RBM5 RNA binding motif protein 5 0.629039
NPB neuropeptide B 0.627335
RARS2 arginyl-tRNA synthetase 2, mitochondrial 0.625206
EPRS glutamyl-prolyl-tRNA synthetase 0.588456
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa 0.553491
PSPC1 paraspeckle component 1 0.543587
FBLL1 fibrillarin-like 1 0.54194
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 0.535772
RAE1 ribonucleic acid export 1 0.533309
SMC6 structural maintenance of chromosomes 6 0.51694
CLK1 CDC-like kinase 1 0.512862
MEOX2 mesenchyme homeobox 2 0.503099
SNRPA small nuclear ribonucleoprotein polypeptide A 0.4958
SSX1 synovial sarcoma, X breakpoint 1 0.495395
CNGB1 cyclic nucleotide gated channel beta 1 0.482064
EIF4A3 eukaryotic translation initiation factor 4A3 0.446465
MAGOHB mago-nashi homolog B (Drosophila) 0.446069
MAGOH mago-nashi homolog, proliferation-associated (Drosophila) 0.440124
CCNH cyclin H 0.412992
FUS FUS RNA binding protein 0.398587
SRSF1 serine/arginine-rich splicing factor 1 0.395485
DRD2 dopamine receptor D2 0.395098
WARS tryptophanyl-tRNA synthetase 0.387751
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.383895
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.367388
SMC5 structural maintenance of chromosomes 5 0.364713
RBM10 RNA binding motif protein 10 0.354422
SOCS1 suppressor of cytokine signaling 1 0.351002
DEK DEK proto-oncogene 0.349863
PROCR protein C receptor, endothelial 0.342664
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled 0.338884
CPSF1 cleavage and polyadenylation specific factor 1, 160kDa 0.325702
RARS arginyl-tRNA synthetase 0.318579
IFNGR1 interferon gamma receptor 1 0.286245
HSPB1 heat shock 27kDa protein 1 0.277038
SLBP stem-loop binding protein 0.273367
NONO non-POU domain containing, octamer-binding 0.269335
RBMY1F RNA binding motif protein, Y-linked, family 1, member F 0.26239
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.260202
DNTT DNA nucleotidylexotransferase 0.24424
PABPN1 poly(A) binding protein, nuclear 1 0.227041
CYLD cylindromatosis (turban tumor syndrome) 0.22279
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.217511
HEXIM1 hexamethylene bis-acetamide inducible 1 0.215761
RBMY1J RNA binding motif protein, Y-linked, family 1, member J 0.214366
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.180339
STAT2 signal transducer and activator of transcription 2, 113kDa 0.176305
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.175745
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.172201
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.168847
EDNRB endothelin receptor type B 0.167366
RANBP2 RAN binding protein 2 0.165231
ESR1 estrogen receptor 1 0.164089
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.160053
PABPC1 poly(A) binding protein, cytoplasmic 1 0.157943