integumentary system benign neoplasm Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description An organ system benign neoplasm located_in the integumentary system organs. (Human Disease Ontology, DOID_0060121)
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Genes

349 genes co-occuring with the disease integumentary system benign neoplasm in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD34 CD34 molecule 1.89963
CD68 CD68 molecule 1.77586
ENO2 enolase 2 (gamma, neuronal) 1.71317
CLEC2A C-type lectin domain family 2, member A 1.61039
PIP prolactin-induced protein 1.4755
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 1.46891
HAVCR1 hepatitis A virus cellular receptor 1 1.43508
HBA1 hemoglobin, alpha 1 1.4342
HBA2 hemoglobin, alpha 2 1.40876
FOXO4 forkhead box O4 1.38472
KRT14 keratin 14, type I 1.38123
GLA galactosidase, alpha 1.34722
CYLD cylindromatosis (turban tumor syndrome) 1.31319
KRT7 keratin 7, type II 1.28654
KRT5 keratin 5, type II 1.23039
GFAP glial fibrillary acidic protein 1.19014
EWSR1 EWS RNA-binding protein 1 1.16863
LYZ lysozyme 1.16563
DHRS1 dehydrogenase/reductase (SDR family) member 1 1.05639
KRT20 keratin 20, type I 1.03788
MAML2 mastermind-like 2 (Drosophila) 1.02397
NAGA N-acetylgalactosaminidase, alpha- 0.984743
KITLG KIT ligand 0.982636
S100A6 S100 calcium binding protein A6 0.980952
TP53 tumor protein p53 0.967502
MLANA melan-A 0.95369
B3GAT1 beta-1,3-glucuronyltransferase 1 0.948685
MIB1 mindbomb E3 ubiquitin protein ligase 1 0.939949
F8 coagulation factor VIII, procoagulant component 0.907731
CRTC1 CREB regulated transcription coactivator 1 0.900746
MMP11 matrix metallopeptidase 11 0.86714
PROX1 prospero homeobox 1 0.862228
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.828229
KRT8 keratin 8, type II 0.824538
PDPN podoplanin 0.804846
PLAG1 pleiomorphic adenoma gene 1 0.799103
CALB2 calbindin 2 0.795411
INHA inhibin, alpha 0.795002
VEGFA vascular endothelial growth factor A 0.791721
MB myoglobin 0.783116
CALD1 caldesmon 1 0.781069
MFSD1 major facilitator superfamily domain containing 1 0.78066
IVL involucrin 0.779432
PCNA proliferating cell nuclear antigen 0.778204
S100A9 S100 calcium binding protein A9 0.77207
KRT15 keratin 15, type I 0.769618
ZNF444 zinc finger protein 444 0.767985
MSH2 mutS homolog 2 0.761862
CD163 CD163 molecule 0.752898
PDGFB platelet-derived growth factor beta polypeptide 0.729357
HOXC13 homeobox C13 0.724907
TRAPPC6B trafficking protein particle complex 6B 0.716021
NGFR nerve growth factor receptor 0.689092
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 0.687491
SP8 Sp8 transcription factor 0.684692
SYP synaptophysin 0.677504
PGM1 phosphoglucomutase 1 0.671925
PROM1 prominin 1 0.661197
PORCN porcupine homolog (Drosophila) 0.653671
POU5F1B POU class 5 homeobox 1B 0.647348
COL1A1 collagen, type I, alpha 1 0.64577
S100A2 S100 calcium binding protein A2 0.643404
FUCA1 fucosidase, alpha-L- 1, tissue 0.617094
MRGBP MRG/MORF4L binding protein 0.614356
PROM2 prominin 2 0.609666
MLH1 mutL homolog 1 0.608104
LEF1 lymphoid enhancer-binding factor 1 0.597181
FLT1 fms-related tyrosine kinase 1 0.594454
PGR progesterone receptor 0.584719
PBX1 pre-B-cell leukemia homeobox 1 0.58433
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled 0.577327
ERBB2 erb-b2 receptor tyrosine kinase 2 0.573439
DAND5 DAN domain family member 5, BMP antagonist 0.571884
POU5F1 POU class 5 homeobox 1 0.555568
MKI67 marker of proliferation Ki-67 0.552463
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.54393
FLG filaggrin 0.529608
FLT4 fms-related tyrosine kinase 4 0.524974
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.515725
MANBA mannosidase, beta A, lysosomal 0.513802
S100A3 S100 calcium binding protein A3 0.504207
KDR kinase insert domain receptor 0.487027
TCHH trichohyalin 0.485885
ESR1 estrogen receptor 1 0.484744
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.476772
S100P S100 calcium binding protein P 0.461639
NCAM1 neural cell adhesion molecule 1 0.459751
MITF microphthalmia-associated transcription factor 0.453339
WT1 Wilms tumor 1 0.451454
AR androgen receptor 0.4443
MFGE8 milk fat globule-EGF factor 8 protein 0.434899
FGF2 fibroblast growth factor 2 (basic) 0.426265
PLIN2 perilipin 2 0.426265
CD44 CD44 molecule (Indian blood group) 0.407919
LYPD1 LY6/PLAUR domain containing 1 0.402318
CDC5L cell division cycle 5-like 0.398216
MYOG myogenin (myogenic factor 4) 0.394863
ANTXR1 anthrax toxin receptor 1 0.392257
ADH6 alcohol dehydrogenase 6 (class V) 0.392257
HMGA2 high mobility group AT-hook 2 0.390025
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.387794
PRKCB protein kinase C, beta 0.368149
FUCA2 fucosidase, alpha-L- 2, plasma 0.367779
KCNIP4 Kv channel interacting protein 4 0.366671
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.362978
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.359657
DES desmin 0.355604
C1GALT1C1 C1GALT1-specific chaperone 1 0.354131
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.354131
WDFY2 WD repeat and FYVE domain containing 2 0.348614
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.346042
CHGA chromogranin A 0.330295
CLDN10 claudin 10 0.32993
VWF von Willebrand factor 0.32701
GNPDA1 glucosamine-6-phosphate deaminase 1 0.319726
NES nestin 0.318999
PTPRC protein tyrosine phosphatase, receptor type, C 0.316092
HRAS Harvey rat sarcoma viral oncogene homolog 0.312464
PLIN3 perilipin 3 0.309928
CTHRC1 collagen triple helix repeat containing 1 0.309204
TNC tenascin C 0.307033
PLXNB1 plexin B1 0.307033
MSH6 mutS homolog 6 0.30631
ODC1 ornithine decarboxylase 1 0.305226
NOTCH1 notch 1 0.300533
RND3 Rho family GTPase 3 0.299452
PLIN1 perilipin 1 0.298371
STAB1 stabilin 1 0.296931
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.28616
CLDN1 claudin 1 0.280796
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.280082
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.273664
CLDN7 claudin 7 0.267977
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 0.264077
ANXA11 annexin A11 0.263014
SPP1 secreted phosphoprotein 1 0.26266
FOSL1 FOS-like antigen 1 0.25983
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.255594
NOTO notochord homeobox 0.254183
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha 0.254183
GLB1 galactosidase, beta 1 0.24996
FUS FUS RNA binding protein 0.245046
WIBG within bgcn homolog (Drosophila) 0.233183
NEU3 sialidase 3 (membrane sialidase) 0.228679
FN1 fibronectin 1 0.226952
CCND1 cyclin D1 0.226952
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.226607
AVP arginine vasopressin 0.226262
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.224884
SH3GL1 SH3-domain GRB2-like 1 0.224196
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.222479
SOX10 SRY (sex determining region Y)-box 10 0.220081
CRNN cornulin 0.215992
TYR tyrosinase 0.214975
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.213621
EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 0.210589
LTBP3 latent transforming growth factor beta binding protein 3 0.206913
MYOD1 myogenic differentiation 1 0.204263
KRT19 keratin 19, type I 0.201308
GRIK4 glutamate receptor, ionotropic, kainate 4 0.201308
PAX2 paired box 2 0.200656
TBX2 T-box 2 0.19742
PRKCD protein kinase C, delta 0.19742
IRF9 interferon regulatory factor 9 0.194232
CTAG2 cancer/testis antigen 2 0.1936
BMP2 bone morphogenetic protein 2 0.191097
RGS5 regulator of G-protein signaling 5 0.190786
PTEN phosphatase and tensin homolog 0.189859
ATF3 activating transcription factor 3 0.183835
NRP1 neuropilin 1 0.181798
LTBP2 latent transforming growth factor beta binding protein 2 0.177029
CENPF centromere protein F, 350/400kDa 0.174354
ANXA6 annexin A6 0.170789
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.167682
PROS1 protein S (alpha) 0.163938
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.159658
FOXN1 forkhead box N1 0.158434
DCD dermcidin 0.144155
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.14138
S100A11 S100 calcium binding protein A11 0.132721
AXIN1 axin 1 0.129582
S100A7 S100 calcium binding protein A7 0.129069
CYS1 cystin 1 0.124714
APC adenomatous polyposis coli 0.120039
S100A4 S100 calcium binding protein A4 0.11914
S100A8 S100 calcium binding protein A8 0.111988
KRT10 keratin 10, type I 0.109787
ANXA2 annexin A2 0.103004
VIM vimentin 0.101432
SOX9 SRY (sex determining region Y)-box 9 0.093755
REEP5 receptor accessory protein 5 0.093471
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) 0.093241
OR10A4 olfactory receptor, family 10, subfamily A, member 4 0.092463
TERT telomerase reverse transcriptase 0.089003
CREB1 cAMP responsive element binding protein 1 0.088394
AMACR alpha-methylacyl-CoA racemase 0.086953
HNF4A hepatocyte nuclear factor 4, alpha 0.086676
KRT4 keratin 4, type II 0.08657
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae) 0.085027
FLNA filamin A, alpha 0.084908
PAEP progestagen-associated endometrial protein 0.083934
MUC2 mucin 2, oligomeric mucus/gel-forming 0.083846
GNAS GNAS complex locus 0.083726
IFNA21 interferon, alpha 21 0.083332
YES1 YES proto-oncogene 1, Src family tyrosine kinase 0.083277
LTF lactotransferrin 0.083266
AGA aspartylglucosaminidase 0.083166
PAX8 paired box 8 0.083033
DUX4L8 double homeobox 4 like 8 0.082212
IFNA17 interferon, alpha 17 0.082056
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.081679
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.081522
MIRLET7C microRNA let-7c 0.08132
NANOG Nanog homeobox 0.081117
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 0.080893
OMD osteomodulin 0.080399
DUX4L6 double homeobox 4 like 6 0.07988
TGFBR1 transforming growth factor, beta receptor 1 0.079858
IGF2 insulin-like growth factor 2 0.079767
PYGB phosphorylase, glycogen; brain 0.079744
PTHLH parathyroid hormone-like hormone 0.079619
PYGL phosphorylase, glycogen, liver 0.079551
KRT16 keratin 16, type I 0.07946
HEYL hes-related family bHLH transcription factor with YRPW motif-like 0.079188
EFNA5 ephrin-A5 0.079109
IGFBP7 insulin-like growth factor binding protein 7 0.078882
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.078656
CLDN11 claudin 11 0.077992
PYGM phosphorylase, glycogen, muscle 0.077981
JAG1 jagged 1 0.077946
PAX9 paired box 9 0.077855
FGF9 fibroblast growth factor 9 0.077797
CA9 carbonic anhydrase IX 0.077694
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.077008
PDGFA platelet-derived growth factor alpha polypeptide 0.076893
HEY2 hes-related family bHLH transcription factor with YRPW motif 2 0.076777
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.07665
CXCL14 chemokine (C-X-C motif) ligand 14 0.076245
AXIN2 axin 2 0.076141
CCNE1 cyclin E1 0.076107
FGF10 fibroblast growth factor 10 0.075887
ADGRV1 adhesion G protein-coupled receptor V1 0.075357
FMOD fibromodulin 0.075345
HBZ hemoglobin, zeta 0.074169
APOD apolipoprotein D 0.073832
CDX2 caudal type homeobox 2 0.073832
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.073669
GPC3 glypican 3 0.073118
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.072825
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.072802
KISS1 KiSS-1 metastasis-suppressor 0.072427
COL18A1 collagen, type XVIII, alpha 1 0.072416
TFPI2 tissue factor pathway inhibitor 2 0.072076
SS18 synovial sarcoma translocation, chromosome 18 0.072052
FANCL Fanconi anemia, complementation group L 0.071428
TGFB2 transforming growth factor, beta 2 0.071192
WNT10B wingless-type MMTV integration site family, member 10B 0.071169
NOTCH3 notch 3 0.070827
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.070545
BMP4 bone morphogenetic protein 4 0.070463
FKBP1A FK506 binding protein 1A, 12kDa 0.069882
FGF7 fibroblast growth factor 7 0.069847
HMGA1 high mobility group AT-hook 1 0.069586
H2AFX H2A histone family, member X 0.069515
LMNB1 lamin B1 0.069302
KRTAP11-1 keratin associated protein 11-1 0.06909
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.069078
NOTCH4 notch 4 0.069019
E2F1 E2F transcription factor 1 0.068865
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 0.068652
ACPP acid phosphatase, prostate 0.068271
PITX1 paired-like homeodomain 1 0.067832
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.0675
VEGFB vascular endothelial growth factor B 0.06706
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.06706
FGFR4 fibroblast growth factor receptor 4 0.067048
AFP alpha-fetoprotein 0.067037
LDLR low density lipoprotein receptor 0.066548
GSK3B glycogen synthase kinase 3 beta 0.06562
FH fumarate hydratase 0.065107
ANOS1 anosmin 1 0.064988
PGF placental growth factor 0.064845
ARRB1 arrestin, beta 1 0.064428
GREM1 gremlin 1, DAN family BMP antagonist 0.063749
CA3 carbonic anhydrase III 0.063713
TXN thioredoxin 0.063617
LGALS3 lectin, galactoside-binding, soluble, 3 0.063522
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.063522
FSHR follicle stimulating hormone receptor 0.063378
MYD88 myeloid differentiation primary response 88 0.063247
LAX1 lymphocyte transmembrane adaptor 1 0.063092
THBD thrombomodulin 0.062866
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.06252
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.06221
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.06221
MMP9 matrix metallopeptidase 9 0.060851
RARB retinoic acid receptor, beta 0.060768
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.060661
FGF1 fibroblast growth factor 1 (acidic) 0.059934
FGF4 fibroblast growth factor 4 0.059863
GP5 glycoprotein V (platelet) 0.059268
GSTM2 glutathione S-transferase mu 2 (muscle) 0.059232
SCN10A sodium channel, voltage gated, type X alpha subunit 0.058994
AHR aryl hydrocarbon receptor 0.057819
CS citrate synthase 0.057676
PMEL premelanosome protein 0.056409
IDO1 indoleamine 2,3-dioxygenase 1 0.056386
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.056208
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.056019
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.056007
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.055854
CHEK1 checkpoint kinase 1 0.0557
S100B S100 calcium binding protein B 0.055394
REL v-rel avian reticuloendotheliosis viral oncogene homolog 0.055028
TF transferrin 0.054805
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 0.054805
MIR145 microRNA 145 0.054158
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.054087
TFE3 transcription factor binding to IGHM enhancer 3 0.054052
ETV3 ets variant 3 0.05404
ACTA1 actin, alpha 1, skeletal muscle 0.053782
SELL selectin L 0.053314
NOG noggin 0.05322
PTCH1 patched 1 0.052717
TBX1 T-box 1 0.052554
DCXR dicarbonyl/L-xylulose reductase 0.052134
CSN1S1 casein alpha s1 0.052006
MUC6 mucin 6, oligomeric mucus/gel-forming 0.051983
TG thyroglobulin 0.051785
IFNA1 interferon, alpha 1 0.051669
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.051181
MYH11 myosin, heavy chain 11, smooth muscle 0.051134
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.051099
MYB v-myb avian myeloblastosis viral oncogene homolog 0.050856
TP63 tumor protein p63 0.050844
THY1 Thy-1 cell surface antigen 0.050809
CD209 CD209 molecule 0.050717
NPS neuropeptide S 0.050578
SDC1 syndecan 1 0.05037
TNF tumor necrosis factor 0.050278
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.050255
SDC2 syndecan 2 0.050255
SCN5A sodium channel, voltage gated, type V alpha subunit 0.050232
IGF1R insulin-like growth factor 1 receptor 0.050128
BIRC5 baculoviral IAP repeat containing 5 0.050047
CTSB cathepsin B 0.050047
H3F3A H3 histone, family 3A 0.050047
H3F3B H3 histone, family 3B (H3.3B) 0.050047
DAPK1 death-associated protein kinase 1 0.049989