integrin-mediated signaling pathway Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. (Gene Ontology, GO_0007229)
External Link http://amigo.geneontology.org/amigo/term/GO:0007229
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Genes

78 genes participating in the integrin-mediated signaling pathway biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
ADAM11 ADAM metallopeptidase domain 11
ADAM15 ADAM metallopeptidase domain 15
ADAM9 ADAM metallopeptidase domain 9
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ANGPTL3 angiopoietin-like 3
APOA1 apolipoprotein A-I
BCAR1 breast cancer anti-estrogen resistance 1
C6ORF25 chromosome 6 open reading frame 25
CCM2 cerebral cavernous malformation 2
CD47 CD47 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
COL16A1 collagen, type XVI, alpha 1
COL3A1 collagen, type III, alpha 1
CTGF connective tissue growth factor
CUL3 cullin 3
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DOCK1 dedicator of cytokinesis 1
DST dystonin
ERBB2IP erbb2 interacting protein
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FERMT2 fermitin family member 2
FERMT3 fermitin family member 3
FGR FGR proto-oncogene, Src family tyrosine kinase
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GAB2 GRB2-associated binding protein 2
HCK HCK proto-oncogene, Src family tyrosine kinase
ILK integrin-linked kinase
ITGA1 integrin, alpha 1
ITGA10 integrin, alpha 10
ITGA11 integrin, alpha 11
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGA6 integrin, alpha 6
ITGA7 integrin, alpha 7
ITGA8 integrin, alpha 8
ITGA9 integrin, alpha 9
ITGAD integrin, alpha D
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAV integrin, alpha V
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB1BP1 integrin beta 1 binding protein 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
ITGB5 integrin, beta 5
ITGB6 integrin, beta 6
ITGB7 integrin, beta 7
ITGB8 integrin, beta 8
LAMA5 laminin, alpha 5
LAT linker for activation of T cells
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MYH9 myosin, heavy chain 9, non-muscle
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PLEK pleckstrin
PLP1 proteolipid protein 1
PRKD1 protein kinase D1
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXN paxillin
RCC2 regulator of chromosome condensation 2
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYK spleen tyrosine kinase
TEC tec protein tyrosine kinase
TSPAN32 tetraspanin 32
TYROBP TYRO protein tyrosine kinase binding protein
VAV1 vav 1 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
ZYX zyxin