insulin-responsive compartment Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2. (Gene Ontology, GO_0032593)
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Genes

198 proteins co-occuring with the insulin-responsive compartment cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
SOX17 SRY (sex determining region Y)-box 17 1.73498
GSC2 goosecoid homeobox 2 1.63242
MNX1 motor neuron and pancreas homeobox 1 1.50735
CHRD chordin 1.47231
MIXL1 Mix paired-like homeobox 1.31196
GSC goosecoid homeobox 1.26551
FOXA2 forkhead box A2 1.26234
OTX2 orthodenticle homeobox 2 1.23088
BMP4 bone morphogenetic protein 4 1.1988
PROM1 prominin 1 1.19828
EOMES eomesodermin 1.03279
ZNHIT2 zinc finger, HIT-type containing 2 1.01337
WDR72 WD repeat domain 72 0.980987
MELK maternal embryonic leucine zipper kinase 0.978074
FOXH1 forkhead box H1 0.961187
FGF8 fibroblast growth factor 8 (androgen-induced) 0.950665
BNC2 basonuclin 2 0.937377
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.922791
PHF5A PHD finger protein 5A 0.914376
SHH sonic hedgehog 0.912511
ALX1 ALX homeobox 1 0.911579
INS insulin 0.911113
ALX4 ALX homeobox 4 0.863528
LHX6 LIM homeobox 6 0.811193
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 0.780954
LHX1 LIM homeobox 1 0.778212
SETDB2 SET domain, bifurcated 2 0.753623
NOG noggin 0.736913
SOX2 SRY (sex determining region Y)-box 2 0.724365
OTP orthopedia homeobox 0.709251
TBX1 T-box 1 0.706156
RAX2 retina and anterior neural fold homeobox 2 0.704831
EVX1 even-skipped homeobox 1 0.696905
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.687264
MSX1 msh homeobox 1 0.686827
APLN apelin 0.681591
ANKRD49 ankyrin repeat domain 49 0.681591
DPP10 dipeptidyl-peptidase 10 (non-functional) 0.673328
NANOG Nanog homeobox 0.671159
FOXB1 forkhead box B1 0.664664
MSI2 musashi RNA-binding protein 2 0.643144
DLX1 distal-less homeobox 1 0.640573
LNPEP leucyl/cystinyl aminopeptidase 0.63715
ATG2B autophagy related 2B 0.626483
CAPN1 calpain 1, (mu/I) large subunit 0.616709
FABP7 fatty acid binding protein 7, brain 0.611201
SMAD5-AS1 SMAD5 antisense RNA 1 0.60655
STX6 syntaxin 6 0.605706
IL11 interleukin 11 0.602331
CAMTA1 calmodulin binding transcription activator 1 0.588875
GYS2 glycogen synthase 2 (liver) 0.583012
WNT3 wingless-type MMTV integration site family, member 3 0.576747
HOXA1 homeobox A1 0.573411
MIR137 microRNA 137 0.571329
SOX3 SRY (sex determining region Y)-box 3 0.569664
WNT3A wingless-type MMTV integration site family, member 3A 0.566338
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) 0.561772
PKNOX2 PBX/knotted 1 homeobox 2 0.561772
NANOS3 nanos homolog 3 (Drosophila) 0.557214
LHX8 LIM homeobox 8 0.550186
NES nestin 0.548122
EPHA3 EPH receptor A3 0.537416
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.521432
GLIPR1 GLI pathogenesis-related 1 0.519798
BMP2 bone morphogenetic protein 2 0.509604
TNFRSF10D tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain 0.507977
MSX2 msh homeobox 2 0.507977
SMAD2 SMAD family member 2 0.50635
TRIM33 tripartite motif containing 33 0.499853
HAND2 heart and neural crest derivatives expressed 2 0.490135
IMPACT impact RWD domain protein 0.490135
PRDM14 PR domain containing 14 0.4865
HDGF hepatoma-derived growth factor 0.484079
GTF2IRD1 GTF2I repeat domain containing 1 0.478843
HOXD4 homeobox D4 0.476429
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.475625
DICER1 dicer 1, ribonuclease type III 0.472412
SOX6 SRY (sex determining region Y)-box 6 0.4672
STXBP4 syntaxin binding protein 4 0.462398
FGF4 fibroblast growth factor 4 0.459602
SORT1 sortilin 1 0.452029
WNT2 wingless-type MMTV integration site family member 2 0.452029
FRZB frizzled-related protein 0.442104
CNOT1 CCR4-NOT transcription complex, subunit 1 0.441312
ISL1 ISL LIM homeobox 1 0.43696
TNFRSF10C tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain 0.434196
EGLN1 egl-9 family hypoxia-inducible factor 1 0.432224
DMBX1 diencephalon/mesencephalon homeobox 1 0.425924
HOXD10 homeobox D10 0.425531
DCAF7 DDB1 and CUL4 associated factor 7 0.422782
TGFB1 transforming growth factor, beta 1 0.420428
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.416902
L1CAM L1 cell adhesion molecule 0.412992
WNT1 wingless-type MMTV integration site family, member 1 0.412601
DLX5 distal-less homeobox 5 0.41221
CER1 cerberus 1, DAN family BMP antagonist 0.407529
TBX6 T-box 6 0.403248
SH3RF1 SH3 domain containing ring finger 1 0.401693
CXCL12 chemokine (C-X-C motif) ligand 12 0.397811
SIX6 SIX homeobox 6 0.395873
CES2 carboxylesterase 2 0.393936
GDF5 growth differentiation factor 5 0.390841
C11ORF30 chromosome 11 open reading frame 30 0.386208
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.385822
GIP gastric inhibitory polypeptide 0.383124
BMPER BMP binding endothelial regulator 0.377738
SSTR2 somatostatin receptor 2 0.375818
GLO1 glyoxalase I 0.372749
GCSH glycine cleavage system protein H (aminomethyl carrier) 0.368919
SYNGR2 synaptogyrin 2 0.365477
FOS FBJ murine osteosarcoma viral oncogene homolog 0.365095
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3 0.363567
MSI1 musashi RNA-binding protein 1 0.347587
ZIC1 Zic family member 1 0.343042
HOXA2 homeobox A2 0.339261
PAX6 paired box 6 0.338884
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 0.338506
ETV1 ets variant 1 0.333225
HOXB9 homeobox B9 0.332095
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.324576
INSR insulin receptor 0.324576
BHLHE41 basic helix-loop-helix family, member e41 0.324201
EGFR epidermal growth factor receptor 0.32345
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.31783
DLX3 distal-less homeobox 3 0.317456
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.31596
RANBP9 RAN binding protein 9 0.314839
MAPK10 mitogen-activated protein kinase 10 0.310358
BMP5 bone morphogenetic protein 5 0.309986
INHBA inhibin, beta A 0.309613
PAX9 paired box 9 0.308867
EYA1 EYA transcriptional coactivator and phosphatase 1 0.305888
RBBP5 retinoblastoma binding protein 5 0.304027
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.303283
GNAS GNAS complex locus 0.296601
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.294748
RPL8 ribosomal protein L8 0.286614
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 0.280716
TBC1D4 TBC1 domain family, member 4 0.278141
AMER1 APC membrane recruitment protein 1 0.276671
SMAD4 SMAD family member 4 0.276304
FGF3 fibroblast growth factor 3 0.274835
HOXA5 homeobox A5 0.274101
PTCH1 patched 1 0.272633
PTF1A pancreas specific transcription factor, 1a 0.266774
ASPA aspartoacylase 0.260202
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.259473
CPA1 carboxypeptidase A1 (pancreatic) 0.258745
NOTCH2NL notch 2 N-terminal like 0.25547
NOTCH2 notch 2 0.250026
BMP7 bone morphogenetic protein 7 0.249302
LDB1 LIM domain binding 1 0.249302
OLIG2 oligodendrocyte lineage transcription factor 2 0.248216
PAX4 paired box 4 0.248216
GDF2 growth differentiation factor 2 0.244601
CARS cysteinyl-tRNA synthetase 0.242076
FOXC1 forkhead box C1 0.238478
RLN3 relaxin 3 0.232386
MRAP melanocortin 2 receptor accessory protein 0.227041
CSPG4 chondroitin sulfate proteoglycan 4 0.22385
SOX1 SRY (sex determining region Y)-box 1 0.222083
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 0.221378
DKK1 dickkopf WNT signaling pathway inhibitor 1 0.218563
FGF5 fibroblast growth factor 5 0.217511
CLCN2 chloride channel, voltage-sensitive 2 0.21681
SFRP4 secreted frizzled-related protein 4 0.216111
EN2 engrailed homeobox 2 0.213322
NOTCH1 notch 1 0.211587
ZFX zinc finger protein, X-linked 0.209513
FOXC2 forkhead box C2 0.207108
GOLGA3 golgin A3 0.200328
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.199659
GCG glucagon 0.196999
MRC2 mannose receptor, C type 2 0.196669
MAST4 microtubule associated serine/threonine kinase family member 4 0.194045
STRA8 stimulated by retinoic acid 8 0.192423
TFRC transferrin receptor 0.190814
CDC25C cell division cycle 25C 0.187646
MAT1A methionine adenosyltransferase I, alpha 0.186708
PTEN phosphatase and tensin homolog 0.181524
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.18093
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.179752
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.179167
PCCA propionyl CoA carboxylase, alpha polypeptide 0.176587
SIX3 SIX homeobox 3 0.176587
KLF4 Kruppel-like factor 4 (gut) 0.176305
NR6A1 nuclear receptor subfamily 6, group A, member 1 0.175466
VAMP4 vesicle-associated membrane protein 4 0.174361
NKX2-2 NK2 homeobox 2 0.174361
GDF6 growth differentiation factor 6 0.173543
GTF2I general transcription factor IIi 0.172201
FST follistatin 0.167611
BMP15 bone morphogenetic protein 15 0.16342
DAZL deleted in azoospermia-like 0.162117
UBE2I ubiquitin-conjugating enzyme E2I 0.160254
COL18A1 collagen, type XVIII, alpha 1 0.159074
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.157943
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) 0.157039