insulin receptor complex Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain. (Gene Ontology, GO_0005899)
External Link http://amigo.geneontology.org/amigo/term/GO:0005899
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Genes

3 proteins localized to the insulin receptor complex cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
INSR insulin receptor
IRS1 insulin receptor substrate 1
SORBS1 sorbin and SH3 domain containing 1