inner plexiform layer Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description The layer of the retina composed of the processes of bipolar cells, ganglion cells, and amacrine cells; a layer containing synaptic contacts. (BRENDA Tissue and Enzyme Source Ontology, BTO_0003175)
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Genes

249 proteins co-occuring with the tissue inner plexiform layer in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CHAT choline O-acetyltransferase 1.9964
TH tyrosine hydroxylase 1.88063
RCVRN recoverin 1.81023
GJD2 gap junction protein, delta 2, 36kDa 1.71738
OPN4 opsin 4 1.6141
CALB1 calbindin 1, 28kDa 1.60068
CALB2 calbindin 2 1.57552
PVALB parvalbumin 1.55552
GPHN gephyrin 1.50528
CCNDBP1 cyclin D-type binding-protein 1 1.48317
BSN bassoon presynaptic cytomatrix protein 1.45564
WDR92 WD repeat domain 92 1.36313
TAC1 tachykinin, precursor 1 1.34587
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.33455
GRIA4 glutamate receptor, ionotropic, AMPA 4 1.30433
CTBP2 C-terminal binding protein 2 1.28861
SST somatostatin 1.27919
GJC1 gap junction protein, gamma 1, 45kDa 1.27292
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 1.24431
DSCAM Down syndrome cell adhesion molecule 1.21001
SYP synaptophysin 1.20645
CPLX4 complexin 4 1.18068
IQSEC2 IQ motif and Sec7 domain 2 1.15052
POU4F1 POU class 4 homeobox 1 1.08722
ACHE acetylcholinesterase (Yt blood group) 1.08015
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 1.07971
DLG3 discs, large homolog 3 (Drosophila) 1.06823
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 1.04664
MPP4 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4) 1.04269
SYNPR synaptoporin 1.03346
NPY neuropeptide Y 1.03346
LRIT3 leucine-rich repeat, immunoglobulin-like and transmembrane domains 3 1.03214
CPLX3 complexin 3 1.02294
OPA1 optic atrophy 1 (autosomal dominant) 1.01156
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 1.00152
FAM161B family with sequence similarity 161, member B 0.995425
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.971119
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.956428
IQSEC3 IQ motif and Sec7 domain 3 0.953409
FAT3 FAT atypical cadherin 3 0.937059
GLRA3 glycine receptor, alpha 3 0.928478
SNAP25 synaptosomal-associated protein, 25kDa 0.916923
SYN1 synapsin I 0.91308
VSX2 visual system homeobox 2 0.899871
SACS sacsin molecular chaperone 0.889253
NGB neuroglobin 0.885862
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.881627
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.878243
NTS neurotensin 0.868529
RIT2 Ras-like without CAAX 2 0.865577
THY1 Thy-1 cell surface antigen 0.863891
VEZF1 vascular endothelial zinc finger 1 0.846225
SDK2 sidekick cell adhesion molecule 2 0.810638
FAM161A family with sequence similarity 161, member A 0.807299
PNMA2 paraneoplastic Ma antigen 2 0.801042
RLBP1 retinaldehyde binding protein 1 0.796458
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B 0.792293
NYX nyctalopin 0.786883
PNMT phenylethanolamine N-methyltransferase 0.785635
GRM7 glutamate receptor, metabotropic 7 0.77774
IQSEC1 IQ motif and Sec7 domain 1 0.776909
BDNF brain-derived neurotrophic factor 0.766954
RAX2 retina and anterior neural fold homeobox 2 0.74009
GRM6 glutamate receptor, metabotropic 6 0.738854
STX1A syntaxin 1A (brain) 0.736382
NCAN neurocan 0.732677
EYS eyes shut homolog (Drosophila) 0.726097
CTXN1 cortexin 1 0.725274
STX3 syntaxin 3 0.722398
CNRIP1 cannabinoid receptor interacting protein 1 0.721577
CSAD cysteine sulfinic acid decarboxylase 0.718703
IMPG2 interphotoreceptor matrix proteoglycan 2 0.716241
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4 0.703945
SV2B synaptic vesicle glycoprotein 2B 0.701899
IRX6 iroquois homeobox 6 0.699853
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.696172
RHO rhodopsin 0.688817
NLGN2 neuroligin 2 0.686368
ISL1 ISL LIM homeobox 1 0.686368
DSCAML1 Down syndrome cell adhesion molecule like 1 0.684327
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.67821
MAP1A microtubule-associated protein 1A 0.674543
DNTT DNA nucleotidylexotransferase 0.664775
NUMBL numb homolog (Drosophila)-like 0.658272
CABP5 calcium binding protein 5 0.653807
UNC13A unc-13 homolog A (C. elegans) 0.649344
PADI2 peptidyl arginine deiminase, type II 0.642048
PCDH19 protocadherin 19 0.642048
GRIK1 glutamate receptor, ionotropic, kainate 1 0.634358
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1 0.62991
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.628293
SDK1 sidekick cell adhesion molecule 1 0.613361
ABAT 4-aminobutyrate aminotransferase 0.609332
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.606514
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.604502
CCK cholecystokinin 0.598469
VIP vasoactive intestinal peptide 0.597263
BARHL2 BarH-like homeobox 2 0.597263
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 0.595255
CNTF ciliary neurotrophic factor 0.588031
NBPF1 neuroblastoma breakpoint family, member 1 0.587629
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 0.585625
ABHD6 abhydrolase domain containing 6 0.581218
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.573616
SCGN secretagogin, EF-hand calcium binding protein 0.572418
VSX1 visual system homeobox 1 0.569222
CALCR calcitonin receptor 0.564434
NPS neuropeptide S 0.563637
KIF3A kinesin family member 3A 0.554478
CNR1 cannabinoid receptor 1 (brain) 0.553683
GRM4 glutamate receptor, metabotropic 4 0.547724
GFAP glial fibrillary acidic protein 0.547326
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.540585
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.539793
GNAT1 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1 0.538209
GLUL glutamate-ammonia ligase 0.53267
GUCY2C guanylate cyclase 2C 0.532274
NPR1 natriuretic peptide receptor 1 0.529903
UNC119 unc-119 homolog (C. elegans) 0.527534
GRM2 glutamate receptor, metabotropic 2 0.517284
NCKAP1 NCK-associated protein 1 0.512564
GUCY2D guanylate cyclase 2D, membrane (retina-specific) 0.511778
TACR1 tachykinin receptor 1 0.510599
GPM6A glycoprotein M6A 0.50471
LIN7C lin-7 homolog C (C. elegans) 0.503141
ISL2 ISL LIM homeobox 2 0.497657
GDF5 growth differentiation factor 5 0.493745
GCG glucagon 0.487886
NCALD neurocalcin delta 0.487106
SIGMAR1 sigma non-opioid intracellular receptor 1 0.485156
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7 0.471539
SV2C synaptic vesicle glycoprotein 2C 0.466885
CNTN2 contactin 2 (axonal) 0.466498
SLC30A10 solute carrier family 30, member 10 0.465335
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5 0.461852
NRD1 nardilysin (N-arginine dibasic convertase) 0.459532
GAP43 growth associated protein 43 0.458759
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.454512
VCAN versican 0.454126
RELN reelin 0.452969
DNM3 dynamin 3 0.448731
TULP1 tubby like protein 1 0.447192
FAT2 FAT atypical cadherin 2 0.439123
SORT1 sortilin 1 0.438739
PARD3 par-3 family cell polarity regulator 0.427636
RAB3C RAB3C, member RAS oncogene family 0.423818
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.421148
SDF4 stromal cell derived factor 4 0.420385
CABP1 calcium binding protein 1 0.419242
CAST calpastatin 0.408592
BVES blood vessel epicardial substance 0.405935
PRPH2 peripherin 2 (retinal degeneration, slow) 0.394197
FAT4 FAT atypical cadherin 4 0.393064
NRL neural retina leucine zipper 0.392686
PLXNA3 plexin A3 0.389666
NTF3 neurotrophin 3 0.389666
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6 0.388912
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.388535
NEUROD6 neuronal differentiation 6 0.388158
DLG1 discs, large homolog 1 (Drosophila) 0.387027
GJB5 gap junction protein, beta 5, 31.1kDa 0.387027
TUBG1 tubulin, gamma 1 0.38665
DLG4 discs, large homolog 4 (Drosophila) 0.382884
FAAH fatty acid amide hydrolase 0.37687
SKAP2 src kinase associated phosphoprotein 2 0.374993
CDH7 cadherin 7, type 2 0.371245
SLC38A5 solute carrier family 38, member 5 0.365633
GRM5 glutamate receptor, metabotropic 5 0.36526
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.360036
ASMT acetylserotonin O-methyltransferase 0.353712
SLC32A1 solute carrier family 32 (GABA vesicular transporter), member 1 0.352969
NLGN3 neuroligin 3 0.352598
NELL2 NEL-like 2 (chicken) 0.347038
TRPC4 transient receptor potential cation channel, subfamily C, member 4 0.342602
BCHE butyrylcholinesterase 0.338914
CDH19 cadherin 19, type 2 0.338545
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.33744
LIN7A lin-7 homolog A (C. elegans) 0.331927
SHANK2 SH3 and multiple ankyrin repeat domains 2 0.331194
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.329361
PLXNA4 plexin A4 0.327896
RAB3A RAB3A, member RAS oncogene family 0.32753
RS1 retinoschisin 1 0.326798
PCP2 Purkinje cell protein 2 0.325701
RAB43 RAB43, member RAS oncogene family 0.321685
RERE arginine-glutamic acid dipeptide (RE) repeats 0.307167
MINK1 misshapen-like kinase 1 0.306444
GLRA1 glycine receptor, alpha 1 0.30464
ADORA1 adenosine A1 receptor 0.300679
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.300679
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.295655
CPLX1 complexin 1 0.294223
GCAT glycine C-acetyltransferase 0.291722
RAB3B RAB3B, member RAS oncogene family 0.283191
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.281423
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.281423
MTNR1A melatonin receptor 1A 0.28107
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.274394
RND1 Rho family GTPase 1 0.273346
NEUROD2 neuronal differentiation 2 0.273346
MTNR1B melatonin receptor 1B 0.271952
MACF1 microtubule-actin crosslinking factor 1 0.269521
UBE2K ubiquitin-conjugating enzyme E2K 0.268482
NGFR nerve growth factor receptor 0.267102
CDK5 cyclin-dependent kinase 5 0.265725
CRYBB2 crystallin, beta B2 0.265038
AACS acetoacetyl-CoA synthetase 0.262645
CAPN2 calpain 2, (m/II) large subunit 0.260945
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.257572
RPH3A rabphilin 3A 0.256568
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.254902
GJA1 gap junction protein, alpha 1, 43kDa 0.253248
CNGA3 cyclic nucleotide gated channel alpha 3 0.252919
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 0.25259
PCDH11Y protocadherin 11 Y-linked 0.250953
GRM1 glutamate receptor, metabotropic 1 0.247399
RBP1 retinol binding protein 1, cellular 0.247079
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 0.24676
NOTO notochord homeobox 0.243918
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.242983
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) 0.24052
PCDH11X protocadherin 11 X-linked 0.240216
NLGN1 neuroligin 1 0.239307
SYT2 synaptotagmin II 0.239007
PLP1 proteolipid protein 1 0.236627
SV2A synaptic vesicle glycoprotein 2A 0.235748
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.235748
MAP1B microtubule-associated protein 1B 0.235167
CNTN1 contactin 1 0.232317
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.232039
DPYSL5 dihydropyrimidinase-like 5 0.232039
TPBG trophoblast glycoprotein 0.230931
SYN2 synapsin II 0.230656
MAP2 microtubule-associated protein 2 0.230382
AADAT aminoadipate aminotransferase 0.230382
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.229839
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.229568
TRO trophinin 0.228764
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.228497
ROM1 retinal outer segment membrane protein 1 0.227707
BMP8B bone morphogenetic protein 8b 0.224645
AMPD2 adenosine monophosphate deaminase 2 0.222224
NEFH neurofilament, heavy polypeptide 0.221291
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.220152
GRM8 glutamate receptor, metabotropic 8 0.217974
BHLHE22 basic helix-loop-helix family, member e22 0.217974
LHX1 LIM homeobox 1 0.214765
GYG1 glycogenin 1 0.213112
PPARD peroxisome proliferator-activated receptor delta 0.212413