injury Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Damage inflicted on the body as the direct or indirect result of an external force, with or without disruption of structural continuity. (Experimental Factor Ontology, EFO_0000546)
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Genes

161 proteins co-occuring with the biological term injury in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANXA2 annexin A2
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BAD BCL2-associated agonist of cell death
BCL2 B-cell CLL/lymphoma 2
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CDC25B cell division cycle 25B
CDC42 cell division cycle 42
CDK5 cyclin-dependent kinase 5
CDK6 cyclin-dependent kinase 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHEK1 checkpoint kinase 1
CORO1B coronin, actin binding protein, 1B
COX2
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRTC1 CREB regulated transcription coactivator 1
CRYAB crystallin, alpha B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CYCS cytochrome c, somatic
DNM1L dynamin 1-like
DPYSL2 dihydropyrimidinase-like 2
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EIF4E eukaryotic translation initiation factor 4E
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK1 ELK1, member of ETS oncogene family
FBXL2 F-box and leucine-rich repeat protein 2
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO3 forkhead box O3
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA4 GATA binding protein 4
GFAP glial fibrillary acidic protein
GJA1 gap junction protein, alpha 1, 43kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPK heterogeneous nuclear ribonucleoprotein K
HSF1 heat shock transcription factor 1
HSPA1A heat shock 70kDa protein 1A
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IL1RL1 interleukin 1 receptor-like 1
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KIRREL kin of IRRE like (Drosophila)
KRT17 keratin 17, type I
KRT18 keratin 18, type I
KRT20 keratin 20, type I
KRT8 keratin 8, type II
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
MCU mitochondrial calcium uniporter
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MFN2 mitofusin 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBPC3 myosin binding protein C, cardiac
MYL12B myosin, light chain 12B, regulatory
MYOZ2 myozenin 2
NCF1 neutrophil cytosolic factor 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRK1 opioid receptor, kappa 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP1 poly (ADP-ribose) polymerase 1
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA3 protein disulfide isomerase family A, member 3
PECAM1 platelet/endothelial cell adhesion molecule 1
PFN1 profilin 1
PIDD1 p53-induced death domain protein 1
PKN1 protein kinase N1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PNPLA8 patatin-like phospholipase domain containing 8
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PTK2 protein tyrosine kinase 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SGK1 serum/glucocorticoid regulated kinase 1
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SIK2 salt-inducible kinase 2
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLK STE20-like kinase
SP1 Sp1 transcription factor
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STMN1 stathmin 1
TH tyrosine hydroxylase
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TRPV1 transient receptor potential cation channel, subfamily V, member 1
VASP vasodilator-stimulated phosphoprotein
VDAC1 voltage-dependent anion channel 1
VIM vimentin
WWOX WW domain containing oxidoreductase
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZBTB17 zinc finger and BTB domain containing 17