inflammatory response Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. (Gene Ontology, GO_0006954)
External Link http://amigo.geneontology.org/amigo/term/GO:0006954
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Genes

384 genes participating in the inflammatory response biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR2 atypical chemokine receptor 2
ACVR1 activin A receptor, type I
ADAM8 ADAM metallopeptidase domain 8
ADGRE2 adhesion G protein-coupled receptor E2
ADGRE5 adhesion G protein-coupled receptor E5
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADORA3 adenosine A3 receptor
ADRA2A adrenoceptor alpha 2A
AFAP1L2 actin filament associated protein 1-like 2
AGER advanced glycosylation end product-specific receptor
AGTR2 angiotensin II receptor, type 2
AHCY adenosylhomocysteinase
AHSG alpha-2-HS-glycoprotein
AIF1 allograft inflammatory factor 1
AIM2 absent in melanoma 2
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
AK7 adenylate kinase 7
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX15 arachidonate 15-lipoxygenase
ANXA1 annexin A1
AOAH acyloxyacyl hydrolase (neutrophil)
AOC3 amine oxidase, copper containing 3
AOX1 aldehyde oxidase 1
APCS amyloid P component, serum
APOA2 apolipoprotein A-II
APOC3 apolipoprotein C-III
APOL2 apolipoprotein L, 2
APOL3 apolipoprotein L, 3
ASS1 argininosuccinate synthase 1
ATRN attractin
AXL AXL receptor tyrosine kinase
AZU1 azurocidin 1
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BCL6 B-cell CLL/lymphoma 6
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BDNF brain-derived neurotrophic factor
BLNK B-cell linker
BMP2 bone morphogenetic protein 2
BMP6 bone morphogenetic protein 6
BMPR1B bone morphogenetic protein receptor, type IB
C3 complement component 3
C3AR1 complement component 3a receptor 1
C5 complement component 5
C5AR1 complement component 5a receptor 1
C5AR2 complement component 5a receptor 2
CALCA calcitonin-related polypeptide alpha
CAMK1D calcium/calmodulin-dependent protein kinase ID
CAMK4 calcium/calmodulin-dependent protein kinase IV
CARD18 caspase recruitment domain family, member 18
CCL11 chemokine (C-C motif) ligand 11
CCL13 chemokine (C-C motif) ligand 13
CCL16 chemokine (C-C motif) ligand 16
CCL17 chemokine (C-C motif) ligand 17
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CCL19 chemokine (C-C motif) ligand 19
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL21 chemokine (C-C motif) ligand 21
CCL22 chemokine (C-C motif) ligand 22
CCL23 chemokine (C-C motif) ligand 23
CCL24 chemokine (C-C motif) ligand 24
CCL25 chemokine (C-C motif) ligand 25
CCL26 chemokine (C-C motif) ligand 26
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCL8 chemokine (C-C motif) ligand 8
CCR1 chemokine (C-C motif) receptor 1
CCR2 chemokine (C-C motif) receptor 2
CCR3 chemokine (C-C motif) receptor 3
CCR4 chemokine (C-C motif) receptor 4
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR7 chemokine (C-C motif) receptor 7
CCRL2 chemokine (C-C motif) receptor-like 2
CD14 CD14 molecule
CD163 CD163 molecule
CD180 CD180 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDO1 cysteine dioxygenase type 1
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CELA1 chymotrypsin-like elastase family, member 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CHUK conserved helix-loop-helix ubiquitous kinase
CLEC7A C-type lectin domain family 7, member A
CNR2 cannabinoid receptor 2 (macrophage)
CRH corticotropin releasing hormone
CRHBP corticotropin releasing hormone binding protein
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF1R colony stimulating factor 1 receptor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYSLTR1 cysteinyl leukotriene receptor 1
DAB2IP DAB2 interacting protein
DEFB1 defensin, beta 1
ECM1 extracellular matrix protein 1
ELANE elastase, neutrophil expressed
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
EPHX2 epoxide hydrolase 2, cytoplasmic
F11R F11 receptor
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F8 coagulation factor VIII, procoagulant component
FFAR3 free fatty acid receptor 3
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FPR2 formyl peptide receptor 2
GAL galanin/GMAP prepropeptide
GATA3 GATA binding protein 3
GGT5 gamma-glutamyltransferase 5
GJA1 gap junction protein, alpha 1, 43kDa
GPER1 G protein-coupled estrogen receptor 1
GPR68 G protein-coupled receptor 68
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC4 histone deacetylase 4
HDAC5 histone deacetylase 5
HDAC9 histone deacetylase 9
HIST1H2BA histone cluster 1, H2ba
HMGB1 high mobility group box 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HP haptoglobin
HRH1 histamine receptor H1
HRH4 histamine receptor H4
HYAL1 hyaluronoglucosaminidase 1
HYAL3 hyaluronoglucosaminidase 3
ICAM1 intercellular adhesion molecule 1
IFI16 interferon, gamma-inducible protein 16
IFNA2 interferon, alpha 2
IGFBP4 insulin-like growth factor binding protein 4
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL10 interleukin 10
IL10RB interleukin 10 receptor, beta
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL17B interleukin 17B
IL17C interleukin 17C
IL17D interleukin 17D
IL17F interleukin 17F
IL17RE interleukin 17 receptor E
IL18 interleukin 18
IL18RAP interleukin 18 receptor accessory protein
IL19 interleukin 19
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RAP interleukin 1 receptor accessory protein
IL1RL2 interleukin 1 receptor-like 2
IL1RN interleukin 1 receptor antagonist
IL20 interleukin 20
IL20RB interleukin 20 receptor beta
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL24 interleukin 24
IL25 interleukin 25
IL26 interleukin 26
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL34 interleukin 34
IL36A interleukin 36, alpha
IL36B interleukin 36, beta
IL36G interleukin 36, gamma
IL37 interleukin 37
IL5 interleukin 5
IL5RA interleukin 5 receptor, alpha
IL6 interleukin 6
IL6R interleukin 6 receptor
IL9 interleukin 9
INS insulin
IRAK2 interleukin-1 receptor-associated kinase 2
IRG1 immunoresponsive 1 homolog (mouse)
IRGM immunity-related GTPase family, M
ITCH itchy E3 ubiquitin protein ligase
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB6 integrin, beta 6
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
JAK3 Janus kinase 3
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KDM6B lysine (K)-specific demethylase 6B
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KL klotho
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KNG1 kininogen 1
KRT16 keratin 16, type I
LAT linker for activation of T cells
LBP lipopolysaccharide binding protein
LIAS lipoic acid synthetase
LIPA lipase A, lysosomal acid, cholesterol esterase
LTA4H leukotriene A4 hydrolase
LTB4R leukotriene B4 receptor
LXN latexin
LY86 lymphocyte antigen 86
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
LYZ lysozyme
MAP2K3 mitogen-activated protein kinase kinase 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MBL2 mannose-binding lectin (protein C) 2, soluble
MECOM MDS1 and EVI1 complex locus
MEFV Mediterranean fever
MEP1B meprin A, beta
MGLL monoglyceride lipase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP25 matrix metallopeptidase 25
MRGPRX1 MAS-related GPR, member X1
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MYD88 myeloid differentiation primary response 88
NAIP NLR family, apoptosis inhibitory protein
NCF1 neutrophil cytosolic factor 1
NCR3 natural cytotoxicity triggering receptor 3
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NFAM1 NFAT activating protein with ITAM motif 1
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NFE2L1 nuclear factor, erythroid 2-like 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBID nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
NFRKB nuclear factor related to kappaB binding protein
NFX1 nuclear transcription factor, X-box binding 1
NGF nerve growth factor (beta polypeptide)
NLRC4 NLR family, CARD domain containing 4
NLRP3 NLR family, pyrin domain containing 3
NLRP4 NLR family, pyrin domain containing 4
NMI N-myc (and STAT) interactor
NOD1 nucleotide-binding oligomerization domain containing 1
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NPFF neuropeptide FF-amide peptide precursor
NRROS negative regulator of reactive oxygen species
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUPR1 nuclear protein, transcriptional regulator, 1
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OPRM1 opioid receptor, mu 1
ORM1 orosomucoid 1
ORM2 orosomucoid 2
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PARK7 parkinson protein 7
PARP4 poly (ADP-ribose) polymerase family, member 4
PDPN podoplanin
PF4 platelet factor 4
PF4V1 platelet factor 4 variant 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLA2G2D phospholipase A2, group IID
PLA2G2E phospholipase A2, group IIE
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAA phospholipase A2-activating protein
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein
PLP1 proteolipid protein 1
PLSCR1 phospholipid scramblase 1
PNMA1 paraneoplastic Ma antigen 1
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRCP prolylcarboxypeptidase (angiotensinase C)
PRDX5 peroxiredoxin 5
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PROK2 prokineticin 2
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTAFR platelet-activating factor receptor
PTGDR prostaglandin D2 receptor (DP)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGES prostaglandin E synthase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTX3 pentraxin 3, long
PXK PX domain containing serine/threonine kinase
PYCARD PYD and CARD domain containing
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBPJ recombination signal binding protein for immunoglobulin kappa J region
REG3A regenerating islet-derived 3 alpha
REG3G regenerating islet-derived 3 gamma
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIPK2 receptor-interacting serine-threonine kinase 2
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S1PR3 sphingosine-1-phosphate receptor 3
SAA1 serum amyloid A1
SAA2 serum amyloid A2
SAA4 serum amyloid A4, constitutive
SCG2 secretogranin II
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCUBE1 signal peptide, CUB domain, EGF-like 1
SDC1 syndecan 1
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
SGMS1 sphingomyelin synthase 1
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SMAD1 SMAD family member 1
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
STAB1 stabilin 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TBK1 TANK-binding kinase 1
TBXA2R thromboxane A2 receptor
TGFB1 transforming growth factor, beta 1
THBS1 thrombospondin 1
THEMIS2 thymocyte selection associated family member 2
TICAM1 toll-like receptor adaptor molecule 1
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR10 toll-like receptor 10
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TNIP3 TNFAIP3 interacting protein 3
TOLLIP toll interacting protein
TP73 tumor protein p73
TPST1 tyrosylprotein sulfotransferase 1
TRIL TLR4 interactor with leucine-rich repeats
TSC2 tuberous sclerosis 2
TSPAN2 tetraspanin 2
TUSC2 tumor suppressor candidate 2
UCN urocortin
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1
XCR1 chemokine (C motif) receptor 1
ZNF580 zinc finger protein 580