infections Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

310 genes co-occuring with the biological term infections in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADA adenosine deaminase
ADM adrenomedullin
ADRBK1 adrenergic, beta, receptor kinase 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALAD aminolevulinate dehydratase
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
APOE apolipoprotein E
AREG amphiregulin
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
BPI bactericidal/permeability-increasing protein
BPIFA1 BPI fold containing family A, member 1
BRD4 bromodomain containing 4
BST2 bone marrow stromal cell antigen 2
BTLA B and T lymphocyte associated
C1QA complement component 1, q subcomponent, A chain
C1QBP complement component 1, q subcomponent binding protein
C2 complement component 2
C4A complement component 4A (Rodgers blood group)
C5 complement component 5
C6 complement component 6
CALCA calcitonin-related polypeptide alpha
CAMP cathelicidin antimicrobial peptide
CARD9 caspase recruitment domain family, member 9
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL3L1 chemokine (C-C motif) ligand 3-like 1
CCL5 chemokine (C-C motif) ligand 5
CCR1 chemokine (C-C motif) receptor 1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1A CD1a molecule
CD1D CD1d molecule
CD1E CD1e molecule
CD209 CD209 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD46 CD46 molecule, complement regulatory protein
CD59 CD59 molecule, complement regulatory protein
CD63 CD63 molecule
CD81 CD81 molecule
CD83 CD83 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CFH complement factor H
CFI complement factor I
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLDN1 claudin 1
CLEC7A C-type lectin domain family 7, member A
CPT2 carnitine palmitoyltransferase 2
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CREB1 cAMP responsive element binding protein 1
CRLS1 cardiolipin synthase 1
CRP C-reactive protein, pentraxin-related
CTCF CCCTC-binding factor (zinc finger protein)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXADR coxsackie virus and adenovirus receptor
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYBB cytochrome b-245, beta polypeptide
CYLD cylindromatosis (turban tumor syndrome)
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCD dermcidin
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFA1 defensin, alpha 1
DEFA3 defensin, alpha 3, neutrophil-specific
DEFA5 defensin, alpha 5, Paneth cell-specific
DEFB1 defensin, beta 1
DMBT1 deleted in malignant brain tumors 1
DNM2 dynamin 2
DOCK8 dedicator of cytokinesis 8
DPP4 dipeptidyl-peptidase 4
DSG2 desmoglein 2
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
EMD emerin
ERVW-1 endogenous retrovirus group W, member 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FASN fatty acid synthase
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXP3 forkhead box P3
FPR1 formyl peptide receptor 1
FUT2 fucosyltransferase 2 (secretor status included)
G6PD glucose-6-phosphate dehydrogenase
GH1 growth hormone 1
GJB2 gap junction protein, beta 2, 26kDa
GOLM1 golgi membrane protein 1
GSTM1 glutathione S-transferase mu 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HAMP hepcidin antimicrobial peptide
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HLA-G major histocompatibility complex, class I, G
HMGB1 high mobility group box 1
HP haptoglobin
ICAM1 intercellular adhesion molecule 1
IDO1 indoleamine 2,3-dioxygenase 1
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNA2 interferon, alpha 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNL1 interferon, lambda 1
IFNL2 interferon, lambda 2
IFNL3 interferon, lambda 3
IGF2 insulin-like growth factor 2
IGF2R insulin-like growth factor 2 receptor
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL15 interleukin 15
IL17A interleukin 17A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RL1 interleukin 1 receptor-like 1
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL2RG interleukin 2 receptor, gamma
IL32 interleukin 32
IL33 interleukin 33
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7R interleukin 7 receptor
IRAK1 interleukin-1 receptor-associated kinase 1
IRAK3 interleukin-1 receptor-associated kinase 3
IRAK4 interleukin-1 receptor-associated kinase 4
IRF3 interferon regulatory factor 3
IRF9 interferon regulatory factor 9
IRGM immunity-related GTPase family, M
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAV integrin, alpha V
ITGB6 integrin, beta 6
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KIR2DL5B killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5B
KIR2DS5 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 5
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LCN2 lipocalin 2
LGALS3 lectin, galactoside-binding, soluble, 3
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMAN1 lectin, mannose-binding, 1
LOC647275 purine nucleoside phosphorylase pseudogene
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTF lactotransferrin
LY96 lymphocyte antigen 96
MAL mal, T-cell differentiation protein
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MASP2 mannan-binding lectin serine peptidase 2
MAVS mitochondrial antiviral signaling protein
MBL2 mannose-binding lectin (protein C) 2, soluble
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146A microRNA 146a
MIR23B microRNA 23b
MIR2909 microRNA 2909
MIR30B microRNA 30b
MLH1 mutL homolog 1
MPV17 MpV17 mitochondrial inner membrane protein
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MX1 MX dynamin-like GTPase 1
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPPB natriuretic peptide B
NUP62 nucleoporin 62kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OGG1 8-oxoguanine DNA glycosylase
OSM oncostatin M
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PCBP1 poly(rC) binding protein 1
PCBP2 poly(rC) binding protein 2
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PGLYRP2 peptidoglycan recognition protein 2
PHEX phosphate regulating endopeptidase homolog, X-linked
PIAS2 protein inhibitor of activated STAT, 2
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PML promyelocytic leukemia
PON2 paraoxonase 2
PPARG peroxisome proliferator-activated receptor gamma
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRF1 perforin 1 (pore forming protein)
PROM1 prominin 1
PROS1 protein S (alpha)
PRPS1 phosphoribosyl pyrophosphate synthetase 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTX3 pentraxin 3, long
PVRL4 poliovirus receptor-related 4
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RHOH ras homolog family member H
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNASE3 ribonuclease, RNase A family, 3
RNASE7 ribonuclease, RNase A family, 7
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SAA1 serum amyloid A1
SCARB1 scavenger receptor class B, member 1
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SFTPA1 surfactant protein A1
SFTPB surfactant protein B
SFTPD surfactant protein D
SGPL1 sphingosine-1-phosphate lyase 1
SHBG sex hormone-binding globulin
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLPI secretory leukocyte peptidase inhibitor
SOCS1 suppressor of cytokine signaling 1
SOD1 superoxide dismutase 1, soluble
SP110 SP110 nuclear body protein
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRSF3 serine/arginine-rich splicing factor 3
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TARBP2 TAR (HIV-1) RNA binding protein 2
TBK1 TANK-binding kinase 1
TBX21 T-box 21
TF transferrin
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TMEM173 transmembrane protein 173
TNF tumor necrosis factor
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TP53 tumor protein p53
TPP2 tripeptidyl peptidase II
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TREM1 triggering receptor expressed on myeloid cells 1
TRIM22 tripartite motif containing 22
TSLP thymic stromal lymphopoietin
UCN2 urocortin 2
UPK1B uroplakin 1B
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VIPR2 vasoactive intestinal peptide receptor 2
VLDLR very low density lipoprotein receptor