indoprofen-4832 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the indoprofen-4832 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AAGAB alpha- and gamma-adaptin binding protein
ACTL8 actin-like 8
ADRBK1 adrenergic, beta, receptor kinase 1
AKAP11 A kinase (PRKA) anchor protein 11
ALOX15 arachidonate 15-lipoxygenase
AP3D1 adaptor-related protein complex 3, delta 1 subunit
APC adenomatous polyposis coli
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ATN1 atrophin 1
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP1 bone morphogenetic protein 1
BTF3P11 basic transcription factor 3 pseudogene 11
C11ORF16 chromosome 11 open reading frame 16
C22ORF46 chromosome 22 open reading frame 46
CARD14 caspase recruitment domain family, member 14
CCDC57 coiled-coil domain containing 57
CFLAR CASP8 and FADD-like apoptosis regulator
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
COL1A1 collagen, type I, alpha 1
COL9A3 collagen, type IX, alpha 3
CRY2 cryptochrome circadian clock 2
CTSZ cathepsin Z
CUL7 cullin 7
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DSTYK dual serine/threonine and tyrosine protein kinase
DUSP13 dual specificity phosphatase 13
EHD1 EH-domain containing 1
EXOSC1 exosome component 1
FBLN1 fibulin 1
FBXL7 F-box and leucine-rich repeat protein 7
FGFBP1 fibroblast growth factor binding protein 1
FGL1 fibrinogen-like 1
FKRP fukutin related protein
FMO5 flavin containing monooxygenase 5
FRMD4A FERM domain containing 4A
GRIP2 glutamate receptor interacting protein 2
GSK3A glycogen synthase kinase 3 alpha
HIC2 hypermethylated in cancer 2
HOXA4 homeobox A4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIF1C kinesin family member 1C
LIN7A lin-7 homolog A (C. elegans)
LOC399491
LPIN2 lipin 2
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK7 mitogen-activated protein kinase 7
MDM4 MDM4, p53 regulator
MED15 mediator complex subunit 15
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MST1 macrophage stimulating 1
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NF1 neurofibromin 1
NFRKB nuclear factor related to kappaB binding protein
NFX1 nuclear transcription factor, X-box binding 1
NPTX1 neuronal pentraxin I
NR6A1 nuclear receptor subfamily 6, group A, member 1
NT5M 5',3'-nucleotidase, mitochondrial
OSGIN2 oxidative stress induced growth inhibitor family member 2
PARD6B par-6 family cell polarity regulator beta
PAX5 paired box 5
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
QKI QKI, KH domain containing, RNA binding
RAB6A RAB6A, member RAS oncogene family
RBM26 RNA binding motif protein 26
RGS19 regulator of G-protein signaling 19
RHEB Ras homolog enriched in brain
RIMS3 regulating synaptic membrane exocytosis 3
RTEL1 regulator of telomere elongation helicase 1
SCG2 secretogranin II
SETD1A SET domain containing 1A
SH3BP2 SH3-domain binding protein 2
SLAMF7 SLAM family member 7
SPON1 spondin 1, extracellular matrix protein
STMN3 stathmin-like 3
SVIL supervillin
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM209 transmembrane protein 209
TMPRSS2 transmembrane protease, serine 2
TRA2A transformer 2 alpha homolog (Drosophila)
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TSC22D4 TSC22 domain family, member 4
ULBP2 UL16 binding protein 2
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VPRBP Vpr (HIV-1) binding protein
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF286A zinc finger protein 286A
ZNF287 zinc finger protein 287
ZNF492 zinc finger protein 492

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ACPP acid phosphatase, prostate
ADM adrenomedullin
AFAP1 actin filament associated protein 1
ATAD2B ATPase family, AAA domain containing 2B
AUTS2 autism susceptibility candidate 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BHLHE41 basic helix-loop-helix family, member e41
BMP15 bone morphogenetic protein 15
C2ORF27A chromosome 2 open reading frame 27A
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CAPN5 calpain 5
CCDC25 coiled-coil domain containing 25
CCDC88C coiled-coil domain containing 88C
CD302 CD302 molecule
CDON cell adhesion associated, oncogene regulated
CEL carboxyl ester lipase
CHKB choline kinase beta
CTSF cathepsin F
CXXC4 CXXC finger protein 4
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
DUSP8 dual specificity phosphatase 8
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FAM169A family with sequence similarity 169, member A
FAM184A family with sequence similarity 184, member A
FAM46C family with sequence similarity 46, member C
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FBXW12 F-box and WD repeat domain containing 12
FER fer (fps/fes related) tyrosine kinase
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GATA4 GATA binding protein 4
GDAP1 ganglioside induced differentiation associated protein 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GRB7 growth factor receptor-bound protein 7
HCAR3 hydroxycarboxylic acid receptor 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST2H2AA3 histone cluster 2, H2aa3
HP1BP3 heterochromatin protein 1, binding protein 3
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
INPP1 inositol polyphosphate-1-phosphatase
IRF2BP1 interferon regulatory factor 2 binding protein 1
KLF13 Kruppel-like factor 13
LAX1 lymphocyte transmembrane adaptor 1
LOC730101 uncharacterized LOC730101
LRP2 low density lipoprotein receptor-related protein 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MGC12488
MMP2 matrix metallopeptidase 2
MRPL41 mitochondrial ribosomal protein L41
MRPL52 mitochondrial ribosomal protein L52
MUC3B mucin 3B, cell surface associated
NCALD neurocalcin delta
NT5DC3 5'-nucleotidase domain containing 3
OLFML2A olfactomedin-like 2A
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVGP1 oviductal glycoprotein 1, 120kDa
PAIP2B poly(A) binding protein interacting protein 2B
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1)
PROS1 protein S (alpha)
PRSS53 protease, serine, 53
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
SAYSD1 SAYSVFN motif domain containing 1
SCHIP1 schwannomin interacting protein 1
SCML2 sex comb on midleg-like 2 (Drosophila)
SCN1B sodium channel, voltage gated, type I beta subunit
SECTM1 secreted and transmembrane 1
SIRT6 sirtuin 6
SKI SKI proto-oncogene
SLC17A2 solute carrier family 17, member 2
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SMR3A submaxillary gland androgen regulated protein 3A
SNTA1 syntrophin, alpha 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STEAP1 six transmembrane epithelial antigen of the prostate 1
STEAP4 STEAP family member 4
STON1 stonin 1
STRA6 stimulated by retinoic acid 6
SYCP2 synaptonemal complex protein 2
TDRD1 tudor domain containing 1
TEX40 testis expressed 40
TLR5 toll-like receptor 5
TMEM212 transmembrane protein 212
TMEM53 transmembrane protein 53
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPK2 uroplakin 2
ZSCAN26 zinc finger and SCAN domain containing 26