indoprofen-3007 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the indoprofen-3007 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACVR1B activin A receptor, type IB
AGFG2 ArfGAP with FG repeats 2
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ANGPTL2 angiopoietin-like 2
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ATXN2L ataxin 2-like
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BTD biotinidase
CA5B carbonic anhydrase VB, mitochondrial
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CD68 CD68 molecule
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CYHR1 cysteine/histidine-rich 1
DCN decorin
DGKE diacylglycerol kinase, epsilon 64kDa
DNMBP dynamin binding protein
DOK3 docking protein 3
DRD2 dopamine receptor D2
EGOT eosinophil granule ontogeny transcript (non-protein coding)
EHMT1 euchromatic histone-lysine N-methyltransferase 1
FKBP9 FK506 binding protein 9, 63 kDa
FLJ11292
FLRT2 fibronectin leucine rich transmembrane protein 2
GALC galactosylceramidase
GAST gastrin
GH1 growth hormone 1
GLG1 golgi glycoprotein 1
GLS glutaminase
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GVINP1 GTPase, very large interferon inducible pseudogene 1
HCG4 HLA complex group 4 (non-protein coding)
HIF3A hypoxia inducible factor 3, alpha subunit
HIST1H2BC histone cluster 1, H2bc
HIST1H3C histone cluster 1, H3c
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
IFNW1 interferon, omega 1
IGLV3-19 immunoglobulin lambda variable 3-19
INCENP inner centromere protein antigens 135/155kDa
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KDSR 3-ketodihydrosphingosine reductase
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF5 Kruppel-like factor 5 (intestinal)
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMA4 laminin, alpha 4
LIMD2 LIM domain containing 2
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LOC1720 dihydrofolate reductase pseudogene
LRP1 low density lipoprotein receptor-related protein 1
MCAM melanoma cell adhesion molecule
MFAP3L microfibrillar-associated protein 3-like
MLXIP MLX interacting protein
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MRPS12 mitochondrial ribosomal protein S12
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NFE2L3 nuclear factor, erythroid 2-like 3
NHLH2 nescient helix loop helix 2
OGFR opioid growth factor receptor
ORAI2 ORAI calcium release-activated calcium modulator 2
PAIP2B poly(A) binding protein interacting protein 2B
PCDHGA8 protocadherin gamma subfamily A, 8
PCSK5 proprotein convertase subtilisin/kexin type 5
PICK1 protein interacting with PRKCA 1
PLXDC1 plexin domain containing 1
PRKD1 protein kinase D1
PTCRA pre T-cell antigen receptor alpha
PTGIS prostaglandin I2 (prostacyclin) synthase
PYGB phosphorylase, glycogen; brain
RASAL2 RAS protein activator like 2
RNF39 ring finger protein 39
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
RUFY3 RUN and FYVE domain containing 3
SCG3 secretogranin III
SCIN scinderin
SFTPA2 surfactant protein A2
SLC12A8 solute carrier family 12, member 8
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SOCS2 suppressor of cytokine signaling 2
SSBP2 single-stranded DNA binding protein 2
SSH3 slingshot protein phosphatase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
TAAR5 trace amine associated receptor 5
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPT1 transmembrane anterior posterior transformation 1
TBC1D22B TBC1 domain family, member 22B
TMEM51 transmembrane protein 51
TSC22D4 TSC22 domain family, member 4
TUBA4B tubulin, alpha 4b
TUBB7P tubulin, beta 7, pseudogene
TYMP thymidine phosphorylase
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VCX2 variable charge, X-linked 2
VSNL1 visinin-like 1
WDR59 WD repeat domain 59
ZNF500 zinc finger protein 500

decreased expression

Symbol Name
ADGB androglobin
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BCAR3 breast cancer anti-estrogen resistance 3
BHMT2 betaine--homocysteine S-methyltransferase 2
BTF3P11 basic transcription factor 3 pseudogene 11
BTF3P12 basic transcription factor 3 pseudogene 12
C3ORF18 chromosome 3 open reading frame 18
C5AR1 complement component 5a receptor 1
C8A complement component 8, alpha polypeptide
CELP carboxyl ester lipase pseudogene
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CORT cortistatin
CROT carnitine O-octanoyltransferase
CTSV cathepsin V
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DDN dendrin
DOLK dolichol kinase
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM106A family with sequence similarity 106, member A
FBRS fibrosin
FKBPL FK506 binding protein like
FLRT1 fibronectin leucine rich transmembrane protein 1
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H2AI histone cluster 1, H2ai
HIST1H3G histone cluster 1, H3g
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HOXA2 homeobox A2
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFNA14 interferon, alpha 14
IFT140 intraflagellar transport 140
IL11RA interleukin 11 receptor, alpha
IL2 interleukin 2
IPO4 importin 4
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KDM8 lysine (K)-specific demethylase 8
KLHDC4 kelch domain containing 4
KRT12 keratin 12, type I
LTBP2 latent transforming growth factor beta binding protein 2
LY6D lymphocyte antigen 6 complex, locus D
LZTR1 leucine-zipper-like transcription regulator 1
MAP6D1 MAP6 domain containing 1
MCOLN1 mucolipin 1
METTL21B methyltransferase like 21B
MRGBP MRG/MORF4L binding protein
MRPS18C mitochondrial ribosomal protein S18C
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NMUR1 neuromedin U receptor 1
NOL12 nucleolar protein 12
ODF2 outer dense fiber of sperm tails 2
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OSBP2 oxysterol binding protein 2
PLAT plasminogen activator, tissue
PLS1 plastin 1
PRSS53 protease, serine, 53
RAB3A RAB3A, member RAS oncogene family
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RCAN3 RCAN family member 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHOBTB2 Rho-related BTB domain containing 2
SCRT1 scratch family zinc finger 1
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SFRP5 secreted frizzled-related protein 5
SIGLEC15 sialic acid binding Ig-like lectin 15
SIT1 signaling threshold regulating transmembrane adaptor 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STBD1 starch binding domain 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TAGLN transgelin
TCHH trichohyalin
TFDP3 transcription factor Dp family, member 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMC5 transmembrane channel-like 5
TMEM140 transmembrane protein 140
TRPV6 transient receptor potential cation channel, subfamily V, member 6
UPK3A uroplakin 3A
VEGFC vascular endothelial growth factor C
YPEL1 yippee-like 1 (Drosophila)
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF222 zinc finger protein 222
ZNF286A zinc finger protein 286A
ZNF385D zinc finger protein 385D
ZNF415 zinc finger protein 415
ZNF671 zinc finger protein 671
ZNF816 zinc finger protein 816
ZNF862 zinc finger protein 862
ZSCAN16 zinc finger and SCAN domain containing 16