indometacin-7409 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the indometacin-7409 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ADTRP androgen-dependent TFPI-regulating protein
AKR1C2 aldo-keto reductase family 1, member C2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
AQP3 aquaporin 3 (Gill blood group)
ARTN artemin
BAHCC1 BAH domain and coiled-coil containing 1
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BMP2K BMP2 inducible kinase
BTN2A2 butyrophilin, subfamily 2, member A2
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF29 chromosome 22 open reading frame 29
CALCOCO1 calcium binding and coiled-coil domain 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CD6 CD6 molecule
CD83 CD83 molecule
CDC25A cell division cycle 25A
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CTAGE5 CTAGE family, member 5
CTNNBIP1 catenin, beta interacting protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DGKQ diacylglycerol kinase, theta 110kDa
DIO2 deiodinase, iodothyronine, type II
DMPK dystrophia myotonica-protein kinase
EPHB2 EPH receptor B2
ERCC2 excision repair cross-complementation group 2
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
F8 coagulation factor VIII, procoagulant component
FAAH fatty acid amide hydrolase
FAM65A family with sequence similarity 65, member A
FGFR2 fibroblast growth factor receptor 2
GATA2 GATA binding protein 2
GRB10 growth factor receptor-bound protein 10
GSTA3 glutathione S-transferase alpha 3
HAUS5 HAUS augmin-like complex, subunit 5
HCFC1 host cell factor C1
HDAC4 histone deacetylase 4
HMHA1 histocompatibility (minor) HA-1
IL2RG interleukin 2 receptor, gamma
IL4R interleukin 4 receptor
INHBA inhibin, beta A
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KDM6A lysine (K)-specific demethylase 6A
KLF9 Kruppel-like factor 9
KRT8 keratin 8, type II
LMNA lamin A/C
LRRC37A3 leucine rich repeat containing 37, member A3
MAPK11 mitogen-activated protein kinase 11
MAPK8 mitogen-activated protein kinase 8
MBNL2 muscleblind-like splicing regulator 2
MBOAT7 membrane bound O-acyltransferase domain containing 7
MUC2 mucin 2, oligomeric mucus/gel-forming
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVB12B multivesicular body subunit 12B
MYCL v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDE1 nudE neurodevelopment protein 1
NDRG2 NDRG family member 2
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
OVGP1 oviductal glycoprotein 1, 120kDa
PAPPA2 pappalysin 2
PDGFB platelet-derived growth factor beta polypeptide
PHF20L1 PHD finger protein 20-like 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCD1 phospholipase C, delta 1
PODNL1 podocan-like 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PVT1 Pvt1 oncogene (non-protein coding)
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBKS ribokinase
RGSL1 regulator of G-protein signaling like 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCAPER S-phase cyclin A-associated protein in the ER
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH2B1 SH2B adaptor protein 1
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLN sarcolipin
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SOS2 son of sevenless homolog 2 (Drosophila)
SOX12 SRY (sex determining region Y)-box 12
TCF20 transcription factor 20 (AR1)
TUBGCP2 tubulin, gamma complex associated protein 2
USB1 U6 snRNA biogenesis 1
VIPR2 vasoactive intestinal peptide receptor 2
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR19 WD repeat domain 19
WWP2 WW domain containing E3 ubiquitin protein ligase 2
ZBTB14 zinc finger and BTB domain containing 14
ZNF287 zinc finger protein 287
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
AHDC1 AT hook, DNA binding motif, containing 1
AKR1C3 aldo-keto reductase family 1, member C3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP10 Rho GTPase activating protein 10
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
C21ORF91 chromosome 21 open reading frame 91
C7ORF43 chromosome 7 open reading frame 43
CASD1 CAS1 domain containing 1
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CISH cytokine inducible SH2-containing protein
CKB creatine kinase, brain
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CROT carnitine O-octanoyltransferase
CSNK2A2 casein kinase 2, alpha prime polypeptide
DCK deoxycytidine kinase
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DEAF1 DEAF1 transcription factor
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DENND1A DENN/MADD domain containing 1A
DNM1 dynamin 1
ECHDC2 enoyl CoA hydratase domain containing 2
ECSIT ECSIT signalling integrator
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EXOC5 exocyst complex component 5
FAM188A family with sequence similarity 188, member A
FBXL15 F-box and leucine-rich repeat protein 15
GAREM GRB2 associated, regulator of MAPK1
GJA1 gap junction protein, alpha 1, 43kDa
GPRASP1 G protein-coupled receptor associated sorting protein 1
GTPBP2 GTP binding protein 2
HEATR3 HEAT repeat containing 3
HOXC11 homeobox C11
HP1BP3 heterochromatin protein 1, binding protein 3
IMPAD1 inositol monophosphatase domain containing 1
IPO8 importin 8
KRT13 keratin 13, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRC49 leucine rich repeat containing 49
MED24 mediator complex subunit 24
MOCS3 molybdenum cofactor synthesis 3
MRPL2 mitochondrial ribosomal protein L2
MXRA7 matrix-remodelling associated 7
NABP2 nucleic acid binding protein 2
NHLRC2 NHL repeat containing 2
NME6 NME/NM23 nucleoside diphosphate kinase 6
NPY5R neuropeptide Y receptor Y5
NRSN2 neurensin 2
ORAI3 ORAI calcium release-activated calcium modulator 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PARD6A par-6 family cell polarity regulator alpha
PARG poly (ADP-ribose) glycohydrolase
PDZRN3 PDZ domain containing ring finger 3
PER3 period circadian clock 3
PILRB paired immunoglobin-like type 2 receptor beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAC8 placenta-specific 8
PLD2 phospholipase D2
PNKP polynucleotide kinase 3'-phosphatase
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PROCR protein C receptor, endothelial
QDPR quinoid dihydropteridine reductase
RAB23 RAB23, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RANBP17 RAN binding protein 17
RBM41 RNA binding motif protein 41
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RWDD3 RWD domain containing 3
SCD5 stearoyl-CoA desaturase 5
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
STBD1 starch binding domain 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TCTN1 tectonic family member 1
TESK2 testis-specific kinase 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM57 transmembrane protein 57
TRABD TraB domain containing
TRAPPC13 trafficking protein particle complex 13
TRIM25 tripartite motif containing 25
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPAN1 tetraspanin 1
TSSC4 tumor suppressing subtransferable candidate 4
UFSP2 UFM1-specific peptidase 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR4 WD repeat domain 4
XPC xeroderma pigmentosum, complementation group C
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF266 zinc finger protein 266
ZNF586 zinc finger protein 586