increased tumor growth/size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than expected development of tumorous growth when compared to controls (Mammalian Phenotype Ontology, MP_0003721)
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37 gene mutations causing the increased tumor growth/size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
APC adenomatous polyposis coli
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
CD226 CD226 molecule
CDKN2A cyclin-dependent kinase inhibitor 2A
CXCL16 chemokine (C-X-C motif) ligand 16
CYGB cytoglobin
GPR68 G protein-coupled receptor 68
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
H19 H19, imprinted maternally expressed transcript (non-protein coding)
ICAM1 intercellular adhesion molecule 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IL22RA2 interleukin 22 receptor, alpha 2
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF10 Kruppel-like factor 10
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MIR122 microRNA 122
PAQR3 progestin and adipoQ receptor family member III
PDCD1LG2 programmed cell death 1 ligand 2
PLCL1 phospholipase C-like 1
PLK3 polo-like kinase 3
POSTN periostin, osteoblast specific factor
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRF1 perforin 1 (pore forming protein)
RNF19B ring finger protein 19B
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S1PR2 sphingosine-1-phosphate receptor 2
SELL selectin L
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
STARD13 StAR-related lipid transfer (START) domain containing 13
TGM2 transglutaminase 2
TICAM1 toll-like receptor adaptor molecule 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10