increased thigmotaxis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than average preference for staying at the perimeter walls of an open area or in an enclosed versus exposed area; may be used as an indicator of increased anxiety response (Mammalian Phenotype Ontology, MP_0002797)
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45 gene mutations causing the increased thigmotaxis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9
ATAT1 alpha tubulin acetyltransferase 1
BBS4 Bardet-Biedl syndrome 4
C12ORF10 chromosome 12 open reading frame 10
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CHD6 chromodomain helicase DNA binding protein 6
CPLX2 complexin 2
CRHBP corticotropin releasing hormone binding protein
CSMD1 CUB and Sushi multiple domains 1
CTNS cystinosin, lysosomal cystine transporter
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DLGAP3 discs, large (Drosophila) homolog-associated protein 3
DRD1 dopamine receptor D1
ESR2 estrogen receptor 2 (ER beta)
FSHR follicle stimulating hormone receptor
GPR26 G protein-coupled receptor 26
GRN granulin
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
KCNH5 potassium channel, voltage gated eag related subfamily H, member 5
KIF13A kinesin family member 13A
L1CAM L1 cell adhesion molecule
LRP5 low density lipoprotein receptor-related protein 5
LRRC7 leucine rich repeat containing 7
LRRTM1 leucine rich repeat transmembrane neuronal 1
NLGN3 neuroligin 3
NPEPPS aminopeptidase puromycin sensitive
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPHN1 oligophrenin 1
PARK2 parkin RBR E3 ubiquitin protein ligase
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
S100A10 S100 calcium binding protein A10
SHANK3 SH3 and multiple ankyrin repeat domains 3
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SNAP25 synaptosomal-associated protein, 25kDa
SPRED1 sprouty-related, EVH1 domain containing 1
SRR serine racemase
TBX1 T-box 1
UCN urocortin
WFS1 Wolfram syndrome 1 (wolframin)