|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||greater likelihood of developing tissue injury mediated by immune complexes; generally involves immune complexes formed in the blood via antibodies encountering circulating antigen; Ag-Ab complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury (Mammalian Phenotype Ontology, MP_0005615)|
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2 gene mutations causing the increased susceptibility to type iii hypersensitivity reaction phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.