increased susceptibility to graft versus host disease Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater likelihood of developing clinical symptoms of anorexia, diarrhea, loss of hair, leukopenia, thrombocytopenia, growth retardation, and eventual death brought about by the a graft versus host reaction, which is an immunological attack mounted by a graft against the host because of tissue incompatibility when immunologically competent cells are transplanted to an immunologically incompetent host (Mammalian Phenotype Ontology, MP_0005672)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005672
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Genes

2 gene mutations causing the increased susceptibility to graft versus host disease phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
IFNGR1 interferon gamma receptor 1
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4