increased susceptibility to atherosclerosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description more likely than normal to develop thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries (Mammalian Phenotype Ontology, MP_0005339)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005339
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Genes

9 gene mutations causing the increased susceptibility to atherosclerosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APOE apolipoprotein E
HPS1 Hermansky-Pudlak syndrome 1
KLF15 Kruppel-like factor 15
LDLR low density lipoprotein receptor
PON1 paraoxonase 1
PON2 paraoxonase 2
RORA RAR-related orphan receptor A
SCARB1 scavenger receptor class B, member 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4