increased small intestinal crypt cell apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of small intestinal crypt cells undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0008800)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008800
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Genes

4 gene mutations causing the increased small intestinal crypt cell apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
TERT telomerase reverse transcriptase
TIGAR TP53 induced glycolysis regulatory phosphatase