increased single-positive t cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater number of T cells bearing either CD4 or CD8 markers on their surface (Mammalian Phenotype Ontology, MP_0008082)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008082
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Genes

21 gene mutations causing the increased single-positive t cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ARID5B AT rich interactive domain 5B (MRF1-like)
ASXL1 additional sex combs like transcriptional regulator 1
ATM ATM serine/threonine kinase
CDK6 cyclin-dependent kinase 6
COL10A1 collagen, type X, alpha 1
DIAPH1 diaphanous-related formin 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
IL2 interleukin 2
IL6ST interleukin 6 signal transducer
LAG3 lymphocyte-activation gene 3
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS2 nitric oxide synthase 2, inducible
NPY1R neuropeptide Y receptor Y1
SGPL1 sphingosine-1-phosphate lyase 1
SPNS2 spinster homolog 2 (Drosophila)
STK4 serine/threonine kinase 4
TCF3 transcription factor 3
TPP2 tripeptidyl peptidase II
TWSG1 twisted gastrulation BMP signaling modulator 1
ZEB1 zinc finger E-box binding homeobox 1
Funding