increased renin activity Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the normal ability of this enzyme to cleave angiotensionogen and create angiotensin I (Mammalian Phenotype Ontology, MP_0005582)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005582
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Genes

13 gene mutations causing the increased renin activity phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
AGTR1 angiotensin II receptor, type 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
DRD3 dopamine receptor D3
NOS2 nitric oxide synthase 2, inducible
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor