increased percent body fat Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description more fat, relative to controls, as a percentage of total body weight (Mammalian Phenotype Ontology, MP_0005458)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0005458
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Genes

49 gene mutations causing the increased percent body fat phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADRA1B adrenoceptor alpha 1B
ADRB3 adrenoceptor beta 3
AR androgen receptor
ASIP agouti signaling protein
BRS3 bombesin-like receptor 3
BSX brain-specific homeobox
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCL13 chemokine (C-C motif) ligand 13
CEP19 centrosomal protein 19kDa
CLOCK clock circadian regulator
COL2A1 collagen, type II, alpha 1
DRD3 dopamine receptor D3
DUSP3 dual specificity phosphatase 3
FOXO1 forkhead box O1
GHR growth hormone receptor
GPM6A glycoprotein M6A
GPR12 G protein-coupled receptor 12
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR39 G protein-coupled receptor 39
GRM8 glutamate receptor, metabotropic 8
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IL18 interleukin 18
IL1R1 interleukin 1 receptor, type I
KPTN kaptin (actin binding protein)
KSR2 kinase suppressor of ras 2
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LRRN3 leucine rich repeat neuronal 3
MC3R melanocortin 3 receptor
MC4R melanocortin 4 receptor
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MRAP2 melanocortin 2 receptor accessory protein 2
MTA1 metastasis associated 1
NCOR2 nuclear receptor corepressor 2
NHLH2 nescient helix loop helix 2
NPY1R neuropeptide Y receptor Y1
OPRM1 opioid receptor, mu 1
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PRLHR prolactin releasing hormone receptor
PYY peptide YY
RDH16 retinol dehydrogenase 16 (all-trans)
RSC1A1 regulatory solute carrier protein, family 1, member 1
SAT1 spermidine/spermine N1-acetyltransferase 1
TERF2IP telomeric repeat binding factor 2, interacting protein
TSN translin
ZEB1 zinc finger E-box binding homeobox 1
Funding