increased pancreatic beta cell mass Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater total physical bulk or volume of a pancreatic beta cell compared to the normal state (Mammalian Phenotype Ontology, MP_0009113)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0009113
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Genes

14 gene mutations causing the increased pancreatic beta cell mass phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
ATF4 activating transcription factor 4
CADM1 cell adhesion molecule 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
INS insulin
INSR insulin receptor
LEP leptin
LEPR leptin receptor
LIPE lipase, hormone-sensitive
MIR184 microRNA 184
PAX2 paired box 2
SCG5 secretogranin V
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SPOP speckle-type POZ protein