increased myocardial infarction size Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increased size of necrotic area from normal of the myocardium resulting from a sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors (Mammalian Phenotype Ontology, MP_0003037)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003037
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Genes

22 gene mutations causing the increased myocardial infarction size phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
APOD apolipoprotein D
BECN1 beclin 1, autophagy related
FGF2 fibroblast growth factor 2 (basic)
GDF15 growth differentiation factor 15
GSK3B glycogen synthase kinase 3 beta
HMOX1 heme oxygenase 1
IL10 interleukin 10
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LIMS2 LIM and senescent cell antigen-like domains 2
MAPK1 mitogen-activated protein kinase 1
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NOS2 nitric oxide synthase 2, inducible
NT5E 5'-nucleotidase, ecto (CD73)
PRKCE protein kinase C, epsilon
RNLS renalase, FAD-dependent amine oxidase
SOD1 superoxide dismutase 1, soluble
STAT1 signal transducer and activator of transcription 1, 91kDa
TGM2 transglutaminase 2
THBD thrombomodulin
TSC2 tuberous sclerosis 2
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta