increased mesothelioma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of neoplasms derived from the lining cells of the pleura and peritoneum, in a specific population in a given time period; is composed of spindle cells or fibrous tissue which may enclose glandlike spaces lined by cuboidal cells (Mammalian Phenotype Ontology, MP_0010309)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0010309
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Genes

3 gene mutations causing the increased mesothelioma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
KRAS Kirsten rat sarcoma viral oncogene homolog
NF2 neurofibromin 2 (merlin)
RINT1 RAD50 interactor 1