increased mast cell number Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than expected number of the cells that are found in almost all tissues, containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation (Mammalian Phenotype Ontology, MP_0000324)
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11 gene mutations causing the increased mast cell number phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AGR2 anterior gradient 2
DSG3 desmoglein 3
FBN1 fibrillin 1
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
LYN LYN proto-oncogene, Src family tyrosine kinase
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
SELE selectin E
SHARPIN SHANK-associated RH domain interactor
SPRED1 sprouty-related, EVH1 domain containing 1
T T, brachyury homolog (mouse)