increased macrophage cytokine production Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater production of macrophage-derived cytokine(s) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels (Mammalian Phenotype Ontology, MP_0011078)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011078
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Genes

4 gene mutations causing the increased macrophage cytokine production phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
FOS FBJ murine osteosarcoma viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
RC3H2 ring finger and CCCH-type domains 2