increased lung adenoma incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the lung, occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0002048)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002048
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Genes

27 gene mutations causing the increased lung adenoma incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
BECN1 beclin 1, autophagy related
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTG3 BTG family, member 3
CASC1 cancer susceptibility candidate 1
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
DCLRE1A DNA cross-link repair 1A
F3 coagulation factor III (thromboplastin, tissue factor)
FEN1 flap structure-specific endonuclease 1
GPRC5A G protein-coupled receptor, class C, group 5, member A
KRAS Kirsten rat sarcoma viral oncogene homolog
LZTS1 leucine zipper, putative tumor suppressor 1
NKX2-8 NK2 homeobox 8
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OGG1 8-oxoguanine DNA glycosylase
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
SMAD9 SMAD family member 9
SSBP2 single-stranded DNA binding protein 2
TNK1 tyrosine kinase, non-receptor, 1
TP53 tumor protein p53
TP63 tumor protein p63
TP73 tumor protein p73
TPX2 TPX2, microtubule-associated
TSC2 tuberous sclerosis 2
USP44 ubiquitin specific peptidase 44
XPA xeroderma pigmentosum, complementation group A
XPC xeroderma pigmentosum, complementation group C