increased kidney apoptosis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the number of cells of the kidney undergoing programmed cell death (Mammalian Phenotype Ontology, MP_0011368)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011368
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Genes

35 gene mutations causing the increased kidney apoptosis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ALMS1 Alstrom syndrome protein 1
BAG6 BCL2-associated athanogene 6
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
C1QA complement component 1, q subcomponent, A chain
CCNI cyclin I
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
DCN decorin
FAS Fas cell surface death receptor
FAT4 FAT atypical cadherin 4
FGFRL1 fibroblast growth factor receptor-like 1
GLIS2 GLIS family zinc finger 2
GSTZ1 glutathione S-transferase zeta 1
HELLS helicase, lymphoid-specific
HMOX1 heme oxygenase 1
HSPA1B heat shock 70kDa protein 1B
ITGA1 integrin, alpha 1
LAMA5 laminin, alpha 5
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LIN7C lin-7 homolog C (C. elegans)
LRRK2 leucine-rich repeat kinase 2
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH2 notch 2
OSR1 odd-skipped related transciption factor 1
PAX2 paired box 2
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
POLB polymerase (DNA directed), beta
POU3F3 POU class 3 homeobox 3
RET ret proto-oncogene
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TRPV5 transient receptor potential cation channel, subfamily V, member 5