increased interleukin-23 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the production or release of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells (Mammalian Phenotype Ontology, MP_0008690)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008690
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Genes

2 gene mutations causing the increased interleukin-23 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACKR4 atypical chemokine receptor 4
AIRE autoimmune regulator