|Dataset||MPO Gene-Phenotype Associations|
|Category||disease or phenotype associations|
|Description||increase in the production or release of a pleiotropic cytokine that regulates immunoglobulin production, plasma cell and Th17 T cell differentiation, CD8+ T cell expansion, and inhibits antigen presentation by dendritic cells (Mammalian Phenotype Ontology, MP_0009057)|
|Downloads & Tools|
1 gene mutations causing the increased interleukin-21 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
|RNF128||ring finger protein 128, E3 ubiquitin protein ligase|