increased interleukin-21 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the production or release of a pleiotropic cytokine that regulates immunoglobulin production, plasma cell and Th17 T cell differentiation, CD8+ T cell expansion, and inhibits antigen presentation by dendritic cells (Mammalian Phenotype Ontology, MP_0009057)
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1 gene mutations causing the increased interleukin-21 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
RNF128 ring finger protein 128, E3 ubiquitin protein ligase