increased interleukin-13 secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the production or release of a cytokine synthesized by T-cells that produces proliferation, immunoglobulin isotype switching, and immunoglobulin production by immature B-cells, and appears to play a role in regulating inflammatory and immune responses (Mammalian Phenotype Ontology, MP_0008672)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008672
Similar Terms
Downloads & Tools

Genes

22 gene mutations causing the increased interleukin-13 secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ATF3 activating transcription factor 3
CD300A CD300a molecule
CD300LF CD300 molecule-like family member f
CISH cytokine inducible SH2-containing protein
DUSP4 dual specificity phosphatase 4
FBN1 fibrillin 1
FLG filaggrin
GPR84 G protein-coupled receptor 84
HAVCR1 hepatitis A virus cellular receptor 1
IL4 interleukin 4
ITK IL2-inducible T-cell kinase
LPAR2 lysophosphatidic acid receptor 2
MEFV Mediterranean fever
MMP9 matrix metallopeptidase 9
MUC2 mucin 2, oligomeric mucus/gel-forming
POU2AF1 POU class 2 associating factor 1
RAD50 RAD50 homolog (S. cerevisiae)
RGS16 regulator of G-protein signaling 16
SIRT7 sirtuin 7
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TSLP thymic stromal lymphopoietin