increased interferon-alpha secretion Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the production or release of one of the type I interferons produced by peripheral blood leukocytes or lymphoblastoid cells that has antiviral activity and activates natural killer cells and B cells (Mammalian Phenotype Ontology, MP_0008562)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008562
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Genes

3 gene mutations causing the increased interferon-alpha secretion phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58
TANK TRAF family member-associated NFKB activator
UNC93B1 unc-93 homolog B1 (C. elegans)