increased gonad tumor incidence Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater than the expected number of an abnormal rapidly proliferating cells in the testis or ovary, usually in the form of a distinct mass, occurring in a specific population in a given time period (Mammalian Phenotype Ontology, MP_0009590)
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31 gene mutations causing the increased gonad tumor incidence phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
AMHR2 anti-Mullerian hormone receptor, type II
AR androgen receptor
ATAD5 ATPase family, AAA domain containing 5
ATM ATM serine/threonine kinase
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CUL9 cullin 9
DCLRE1A DNA cross-link repair 1A
DND1 DND microRNA-mediated repression inhibitor 1
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
HELQ helicase, POLQ-like
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
INHA inhibin, alpha
KITLG KIT ligand
LATS1 large tumor suppressor kinase 1
MCM8 minichromosome maintenance complex component 8
MCM9 minichromosome maintenance complex component 9
MEN1 multiple endocrine neoplasia I
NBN nibrin
NR0B1 nuclear receptor subfamily 0, group B, member 1
PCSK6 proprotein convertase subtilisin/kexin type 6
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RINT1 RAD50 interactor 1
SAV1 salvador family WW domain containing protein 1
SF1 splicing factor 1
SMAD4 SMAD family member 4
SPTBN1 spectrin, beta, non-erythrocytic 1
TOM1L2 target of myb1-like 2 (chicken)
TP53 tumor protein p53