increased fluid intake Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the total amount of fluid taken in over time when compared to the normal state (Mammalian Phenotype Ontology, MP_0011941)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011941
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Genes

84 gene mutations causing the increased fluid intake phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ADCY6 adenylate cyclase 6
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APOE apolipoprotein E
APRT adenine phosphoribosyltransferase
AQP2 aquaporin 2 (collecting duct)
AQP3 aquaporin 3 (Gill blood group)
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
AVP arginine vasopressin
AVPR2 arginine vasopressin receptor 2
CCKBR cholecystokinin B receptor
CCL13 chemokine (C-C motif) ligand 13
CCL3L3 chemokine (C-C motif) ligand 3-like 3
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD63 CD63 molecule
CDK4 cyclin-dependent kinase 4
CHRM3 cholinergic receptor, muscarinic 3
CLN3 ceroid-lipofuscinosis, neuronal 3
CRH corticotropin releasing hormone
CTSA cathepsin A
DRD2 dopamine receptor D2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
EPS8 epidermal growth factor receptor pathway substrate 8
FAAH fatty acid amide hydrolase
FOXA2 forkhead box A2
FXYD4 FXYD domain containing ion transport regulator 4
GDF15 growth differentiation factor 15
GFRA2 GDNF family receptor alpha 2
GLIS2 GLIS family zinc finger 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HPRT1 hypoxanthine phosphoribosyltransferase 1
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
INS insulin
IRS2 insulin receptor substrate 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
LCLAT1 lysocardiolipin acyltransferase 1
LEPR leptin receptor
LEPROT leptin receptor overlapping transcript
MARK4 MAP/microtubule affinity-regulating kinase 4
MCHR1 melanin-concentrating hormone receptor 1
MTSS1 metastasis suppressor 1
MYO7A myosin VIIA
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NOS1 nitric oxide synthase 1 (neuronal)
NPR3 natriuretic peptide receptor 3
NPY1R neuropeptide Y receptor Y1
NPY2R neuropeptide Y receptor Y2
NPY4R neuropeptide Y receptor Y4
NR1H4 nuclear receptor subfamily 1, group H, member 4
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PSAP prosaposin
REN renin
SCARB2 scavenger receptor class B, member 2
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCTR secretin receptor
SIRT1 sirtuin 1
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
TAOK2 TAO kinase 2
TGFB1 transforming growth factor, beta 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV5 transient receptor potential cation channel, subfamily V, member 5
UMOD uromodulin
UNC5C unc-5 homolog C (C. elegans)
UNC79 unc-79 homolog (C. elegans)
UOX urate oxidase, pseudogene
USH1C Usher syndrome 1C (autosomal recessive, severe)
VAMP8 vesicle-associated membrane protein 8
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor