increased fibroblast proliferation Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater the expansion rate of a fibroblast cell population by cell division (Mammalian Phenotype Ontology, MP_0011703)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0011703
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Genes

19 gene mutations causing the increased fibroblast proliferation phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ACP1 acid phosphatase 1, soluble
CACYBP calcyclin binding protein
CBX7 chromobox homolog 7
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
FBXO4 F-box protein 4
ING1 inhibitor of growth family, member 1
IP6K2 inositol hexakisphosphate kinase 2
LATS1 large tumor suppressor kinase 1
LUM lumican
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
NONO non-POU domain containing, octamer-binding
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PHF14 PHD finger protein 14
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PML promyelocytic leukemia
RBL1 retinoblastoma-like 1
TP53 tumor protein p53
VCL vinculin