increased exploration in new environment Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description greater amount of time spent investigating new location (Mammalian Phenotype Ontology, MP_0001415)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001415
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Genes

27 gene mutations causing the increased exploration in new environment phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADRA1B adrenoceptor alpha 1B
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CKB creatine kinase, brain
CLOCK clock circadian regulator
CNR1 cannabinoid receptor 1 (brain)
DISC1 disrupted in schizophrenia 1
DRD3 dopamine receptor D3
ERC2 ELKS/RAB6-interacting/CAST family member 2
EYA3 EYA transcriptional coactivator and phosphatase 3
FMR1 fragile X mental retardation 1
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTT huntingtin
LSAMP limbic system-associated membrane protein
NPAS3 neuronal PAS domain protein 3
OPHN1 oligophrenin 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PDE1B phosphodiesterase 1B, calmodulin-dependent
PFN2 profilin 2
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PTPRF protein tyrosine phosphatase, receptor type, F
S100A1 S100 calcium binding protein A1
SH3KBP1 SH3-domain kinase binding protein 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2