increased circulating interleukin-5 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount in the blood of a cytokine that promotes differentiation and activation of eosinophils; it also triggers activated B-cells to differentiate into immunoglobulin-secreting cells (Mammalian Phenotype Ontology, MP_0008626)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008626
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Genes

5 gene mutations causing the increased circulating interleukin-5 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
FOXP3 forkhead box P3
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
IL13RA1 interleukin 13 receptor, alpha 1
IRF1 interferon regulatory factor 1
TP53 tumor protein p53