increased circulating interleukin-2 level Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description increase in the amount in the blood of a soluble substance elaborated by antigen- or mitogen-stimulated T-cells which induces DNA synthesis in naive lymphocytes (Mammalian Phenotype Ontology, MP_0008599)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0008599
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Genes

7 gene mutations causing the increased circulating interleukin-2 level phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CD44 CD44 molecule (Indian blood group)
IL10 interleukin 10
IL10RA interleukin 10 receptor, alpha
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
MTA2 metastasis associated 1 family, member 2
NOD2 nucleotide-binding oligomerization domain containing 2
RNF128 ring finger protein 128, E3 ubiquitin protein ligase